Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Alexander M. Beck"'
Autor:
Mariella G. Filbin, Sander Lambo, Bernhard Englinger, Olivia A Hack, Sibylle Madlener, Volker Hovestadt, McKenzie Shaw, Marcel Kool, Johannes Gojo, Stefan M. Pfister, Alexander M. Beck, Sanda Alexandrescu
Publikováno v:
Neuro-Oncology. 23:vi7-vi8
Embryonal tumor with multilayered rosettes (ETMR) is a malignant brain tumor that typically occurs in children under the age of three. Most patients die within two years of diagnosis, and more effective, targeted therapies are urgently needed. To bet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff99ec0d1b30c08862e5d708a1eea3c2
https://doi.org/10.1093/neuonc/noab196.026
https://doi.org/10.1093/neuonc/noab196.026
Targeting excessive MYCN expression using MLN8237 and JQ1 impairs the growth of hepatoblastoma cells
Autor:
Kristina Becker, Beate Häberle, R Kappler, Corinna Eberherr, Dietrich von Schweinitz, Christian Vokuhl, Alexander M. Beck
Publikováno v:
International Journal of Oncology.
Hepatoblastoma (HB) is the most common liver tumor in children under the age of 3 years worldwide. While many patients achieve good outcomes with surgical resection and conventional chemotherapy, there is still a high‑risk population that exhibits
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f58c1866adda7f5183930476713fa8c6
https://doi.org/10.3892/ijo.2019.4741
https://doi.org/10.3892/ijo.2019.4741
Autor:
Roland Kappler, Dietrich von Schweinitz, Alexander M. Beck, Beate Häberle, Christian Vokuhl, Michaela Hagemann, Stefano Cairo, Corinna Eberherr
Publikováno v:
Cancer Biology & Therapy. 17:1168-1176
Hepatoblastoma (HB) is the most common liver tumor of childhood, usually occurring in children under the age of 3 y. The prognosis of patients presenting with distant metastasis, vascular invasion and advanced tumor stages remains poor and children t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::557f601e556319bbb72b03d253087d09
https://doi.org/10.1080/15384047.2016.1235664
https://doi.org/10.1080/15384047.2016.1235664
Autor:
Ilon Liu, Neekesh V. Dharia, Nathan Mathewson, Deyao Li, Yang Shi, William Jerome, Hafsa M Mire, Guillaume Kugener, Jun Qi, McKenzie Shaw, Jamie N. Anastas, Tingjian Wang, Francisca Vazquez, Michelle Monje, Caleb A. Lareau, Michael Quezada, Mariella G. Filbin, Maria Trissal, Kimberly Stegmaier, David E. Root, Todd R. Golub, Eshini Panditharatna, Alexander M. Beck, Li Jiang, Olivia A Hack, Lingling Dai
Publikováno v:
Neuro Oncol
Children diagnosed with diffuse intrinsic pontine glioma (DIPG), a type of high grade glioma in the brainstem, currently have a dismal 5-year overall survival of only 2%. The majority of DIPG patients harbor a K27M mutation in histone 3.3 encoding ge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::569ccab53e6ac5323cb2b81a2310e7a8
https://doi.org/10.1093/neuonc/noaa215.391
https://doi.org/10.1093/neuonc/noaa215.391
Autor:
Cyril Neftel, Tracy T. Batchelor, Angel M. Carcaboso, Gerhard Fritsch, Pratiti Bandopadhayay, Andreas Peyrl, Claire Sinai, Mara Popović, Quang-Dé Nguyen, Orit Rozenblatt-Rosen, Christina C. Luo, Itay Tirosh, Michelle Monje, Kai W. Wucherpfennig, Alexander M. Beck, Peter van Galen, Dennis M. Bonal, Gad Getz, Christian Dorfer, Volker Hovestadt, Nathan Mathewson, Mariella G. Filbin, Mark W. Kieran, Kristine Pelton, Keren Yizhak, Rameen Beroukhim, Maria Martinez-Lage, Ravindra Mylvaganam, Kristof Egervari, Christine Haberler, Jaume Mora, Keith L. Ligon, Johannes Gojo, McKenzie Shaw, Christine M. Hebert, Nelli Frank, Bradley E. Bernstein, Todd R. Golub, Christopher Mount, Matthew P. Frosch, Cinzia Lavarino, Thomas Czech, Amedeo A. Azizi, Mario L. Suvà, David N. Louis, Aviv Regev, Liliana Goumnerova, Irene Slavc, Leah E. Escalante
Publikováno v:
Science
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
The cellular composition of H3K27M gliomas Diffuse midline gliomas with histone H3 lysine27-to-methionine mutations (H3K27M-glioma) are an aggressive type of childhood cancer with few options for treatment. Filbin et al. used a single-cell sequencing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::488c4f260a177a7c8e9b5eb440e8f8ef
http://fundanet.fsjd.org/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=14257
http://fundanet.fsjd.org/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=14257
Autor:
Roland Kappler, Stefano Cairo, Ivo Leuschner, Alexander M. Beck, Michaela Kreuder, Thomas Schwarzmayr, Tim M. Strom, Beate Häberle, Dietrich von Schweinitz, Melanie Eichenmüller, Franziska Trippel
Publikováno v:
Journal of Hepatology. 61:1312-1320
Background & Aims Hepatoblastoma (HB) is the most common childhood liver cancer and occasionally presents with histological and clinical features reminiscent of hepatocellular carcinoma (HCC). Identification of molecular mechanisms that drive the neo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc7153b083bfca99822043969792bd2f
https://doi.org/10.1016/j.jhep.2014.08.009
https://doi.org/10.1016/j.jhep.2014.08.009
Autor:
Giuseppe Murante, Gian Luigi Granato, Alexander M. Beck, Veronica Biffi, Klaus Dolag, Cinthia Ragone-Figueroa, Elena Rasia, Susana Planelles, Stefano Borgani, Massimo Gaspari
In this paper we investigate the level of hydrostatic equilibrium (HE) in the intra-cluster medium of simulated galaxy clusters, extracted from state-of-the-art cosmological hydrodynamical simulations performed with the Smoothed-Particle-Hydrodynamic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1aab7581d1b11a1393a13fa468ef5770
http://hdl.handle.net/11368/2891475
http://hdl.handle.net/11368/2891475
Autor:
Alexander M. Beck, Hanna Kotarba, Florian Bürzle, Peter Nielaba, Klaus Dolag, Marcus C. Beck, Annette Geng
Publikováno v:
Monthly Notices of the Royal Astronomical Society. 426:3160-3177
We present simulations of the compact galaxy group Stephan's Quintet (SQ) including magnetic fields, performed with the N-body/smoothed particle hydrodynamics (SPH) code \textsc{Gadget}. The simulations include radiative cooling, star formation and s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1bb892a8e401ba436b99bdc0ae1848e4
https://doi.org/10.1111/j.1365-2966.2012.21902.x
https://doi.org/10.1111/j.1365-2966.2012.21902.x
Autor:
Annette Geng, Hanna Kotarba, Federico Stasyszyn, Klaus Dolag, Alexander M. Beck, Harald Lesch
Publikováno v:
Monthly Notices of the Royal Astronomical Society. 422:2152-2163
An analytical model predicting the growth rates, the absolute growth times and the saturation values of the magnetic field strength within galactic haloes is presented. The analytical results are compared to cosmological MHD simulations of Milky-Way
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7e5013877576859feb2c9eaf3f29297
https://doi.org/10.1111/j.1365-2966.2012.20759.x
https://doi.org/10.1111/j.1365-2966.2012.20759.x
Autor:
Klaus Dolag, Hanna Kotarba, Annette Geng, Florian Bürzle, Peter Nielaba, Federico Stasyszyn, Alexander M. Beck
Publikováno v:
Monthly Notices of the Royal Astronomical Society. 419:3571-3589
We investigate the magnetic field evolution in a series of galaxy minor mergers using the N-body/smoothed particle hydrodynamics (SPH) code \textsc{Gadget}. The simulations include the effects of radiative cooling, star formation and supernova feedba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dfc6cefb31739185fb8f3e04e6d2f2af
https://doi.org/10.1111/j.1365-2966.2011.20001.x
https://doi.org/10.1111/j.1365-2966.2011.20001.x