Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Alexander M van der Linden"'
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 12, Iss 6 (2022)
AbstractDynamic changes in chemoreceptor gene expression levels in sensory neurons are one strategy that an animal can use to modify their responses to dietary changes. However, the mechanisms underlying diet-dependent modulation of chemosensory gene
Externí odkaz:
https://doaj.org/article/89b0e5c3096140c7897a3e85ddad9484
Publikováno v:
PLoS Biology, Vol 18, Iss 4, p e3000220 (2020)
Many lines of evidence point to links between sleep regulation and energy homeostasis, but mechanisms underlying these connections are unknown. During Caenorhabditis elegans sleep, energetic stores are allocated to nonneural tasks with a resultant dr
Externí odkaz:
https://doaj.org/article/c9a5a252b0a34044a0c454a1d57783dd
Autor:
Matthew Gruner, Jeremy Grubbs, Aja McDonagh, Dominic Valdes, Ari Winbush, Alexander M van der Linden
Publikováno v:
PLoS Genetics, Vol 12, Iss 8, p e1006237 (2016)
Food and feeding-state dependent changes in chemoreceptor gene expression may allow Caenorhabditis elegans to modify their chemosensory behavior, but the mechanisms essential for these expression changes remain poorly characterized. We had previously
Externí odkaz:
https://doaj.org/article/ef0a7d005aa54c8992f9e60eac1cd694
Autor:
Matthew Gruner, Dru Nelson, Ari Winbush, Rebecca Hintz, Leesun Ryu, Samuel H Chung, Kyuhyung Kim, Chrisopher V Gabel, Alexander M van der Linden
Publikováno v:
PLoS Genetics, Vol 10, Iss 10, p e1004707 (2014)
Feeding state and food availability can dramatically alter an animals' sensory response to chemicals in its environment. Dynamic changes in the expression of chemoreceptor genes may underlie some of these food and state-dependent changes in chemosens
Externí odkaz:
https://doaj.org/article/90735de4a2be4f829a87170f3f77340f
Autor:
Alexander M van der Linden, Matthew Beverly, Sebastian Kadener, Joseph Rodriguez, Sara Wasserman, Michael Rosbash, Piali Sengupta
Publikováno v:
PLoS Biology, Vol 8, Iss 10, p e1000503 (2010)
Most organisms have an endogenous circadian clock that is synchronized to environmental signals such as light and temperature. Although circadian rhythms have been described in the nematode Caenorhabditis elegans at the behavioral level, these rhythm
Externí odkaz:
https://doaj.org/article/61069ae78dc6433b8979bb307baaf056
Autor:
Femke Simmer, Celine Moorman, Alexander M van der Linden, Ewart Kuijk, Peter V E van den Berghe, Ravi S Kamath, Andrew G Fraser, Julie Ahringer, Ronald H A Plasterk
Publikováno v:
PLoS Biology, Vol 1, Iss 1, p E12 (2003)
RNA-mediated interference (RNAi) is a method to inhibit gene function by introduction of double-stranded RNA (dsRNA). Recently, an RNAi library was constructed that consists of bacterial clones expressing dsRNA, corresponding to nearly 90% of the 19,
Externí odkaz:
https://doaj.org/article/6f3c02ebf8da4328be3d5f0d4392f7b8
Autor:
David Knupp, Brian G. Jorgensen, Hussam Z. Alshareef, Jaffar M. Bhat, Jeremy J. Grubbs, Pedro Miura, Alexander M. van der Linden
Publikováno v:
Aging Cell. 21
Accumulation of circular RNAs (circRNAs) during aging occurs on a genome-wide level for multiple organisms, but its significance is unknown. Generating circRNA loss-of-function mutants is difficult because the vast majority of these RNAs are comprise
Dynamic changes in chemoreceptor gene expression levels in sensory neurons is one strategy that an animal can use to modify their responses to dietary changes. However, the mechanisms underlying diet-dependent modulation of chemosensory gene expressi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7537b69f67061f657baa08a7a9e7504a
https://doi.org/10.1101/2021.10.02.462191
https://doi.org/10.1101/2021.10.02.462191
Publikováno v:
microPublication Biology
kin-29 encodes the C. elegans homolog of mammalian Salt-Inducible Kinases (SIKs). kin-29 mutants are small, have increased propensity to develop into non-reproductive dauer larvae, have reduced chemoreceptor gene expression (Lanjuin and Sengupta, 200
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70e326967a537280030d86a0ff042f5b
Many lines of evidence point to links between sleep regulation and energy homeostasis, but mechanisms underlying these connections are unknown. DuringC. eleganssleep, energetic stores are allocated to non-neural tasks with a resultant drop in the ove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b63a7c16e3313a6bdc591aa9d11168cd