Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Alexander M Sherwood"'
Autor:
Jason Wallach, Andrew B. Cao, Maggie M. Calkins, Andrew J. Heim, Janelle K. Lanham, Emma M. Bonniwell, Joseph J. Hennessey, Hailey A. Bock, Emilie I. Anderson, Alexander M. Sherwood, Hamilton Morris, Robbin de Klein, Adam K. Klein, Bruna Cuccurazzu, James Gamrat, Tilka Fannana, Randy Zauhar, Adam L. Halberstadt, John D. McCorvy
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023)
Abstract Serotonergic psychedelics possess considerable therapeutic potential. Although 5-HT2A receptor activation mediates psychedelic effects, prototypical psychedelics activate both 5-HT2A-Gq/11 and β-arrestin2 transducers, making their respectiv
Externí odkaz:
https://doaj.org/article/30bf5d9d5f33452682a561177a856eb2
Publikováno v:
ACS Omega, Vol 7, Iss 6, Pp 5429-5436 (2022)
Externí odkaz:
https://doaj.org/article/d22db13ce643462d9119d37ae3664e9f
Publikováno v:
ACS Omega, Vol 5, Iss 49, Pp 32067-32075 (2020)
Externí odkaz:
https://doaj.org/article/0f8c554083fd4d65843970a27b753c02
Autor:
Steven W Cotten, Frederick G Strathmann, Frederick S Barrett, Laura Labay, James Mullally, Alexander M Sherwood, Frank Wiegand
Publikováno v:
Clinical Chemistry. 69:319-326
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5013d578c65d39d422c19fb3918a9888
https://doi.org/10.1093/clinchem/hvad016
https://doi.org/10.1093/clinchem/hvad016
Publikováno v:
Acta Crystallographica Section E Crystallographic Communications. 78:550-553
The title compound, baeocystin or 4-phosphoryloxy-N-methyltryptamine {systematic name: 3-[2-(methylazaniumyl)ethyl]-1H-indol-4-yl hydrogen phosphate}, C11H15N2O4P, has a single zwitterionic molecule in the asymmetric unit. The molecule has an intramo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0e403b862cd2ea4189e1db0ac43a20c
https://doi.org/10.1107/s2056989022004467
https://doi.org/10.1107/s2056989022004467
Autor:
Sarah J. Jefferson, Ian Gregg, Mark Dibbs, Clara Liao, Hao Wu, Pasha A. Davoudian, Samuel C. Woodburn, Patrick H. Wehrle, Jeffrey S. Sprouse, Alexander M. Sherwood, Alfred P. Kaye, Christopher Pittenger, Alex C. Kwan
Publikováno v:
Neuropsychopharmacology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e463ccff55f744ab6c81b1a1982ef68e
https://doi.org/10.1038/s41386-023-01572-w
https://doi.org/10.1038/s41386-023-01572-w
Autor:
Sarah J. Jefferson, Ian Gregg, Mark Dibbs, Clara Liao, Hao Wu, Pasha A. Davoudian, Jeffrey S. Sprouse, Alexander M. Sherwood, Alfred P. Kaye, Christopher Pittenger, Alex C. Kwan
Serotonergic psychedelics are gaining increasing interest as potential therapeutics for a range of mental illnesses. Compounds with short-lived subjective effects may be clinically useful because dosing time would be reduced, which may improve patien
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e5a5ec2b0e54fcc34b1df2125a7c46c
https://doi.org/10.1101/2022.11.03.515044
https://doi.org/10.1101/2022.11.03.515044
Autor:
Grant C. Glatfelter, Eline Pottie, John S. Partilla, Alexander M. Sherwood, Kristi Kaylo, Duyen N. K. Pham, Marilyn Naeem, Vamshikrishna Reddy Sammeta, Stacie DeBoer, James A. Golen, Elliott B. Hulley, Christophe P. Stove, Andrew R. Chadeayne, David R. Manke, Michael H. Baumann
Publikováno v:
ACS pharmacologytranslational science. 5(11)
4-Phosphoryloxy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45a73940a66d3a21ee5a9855264027ed
https://pubmed.ncbi.nlm.nih.gov/36407948
https://pubmed.ncbi.nlm.nih.gov/36407948
Autor:
Carol A. Paronis, Jack Bergman, Alexander M. Sherwood, Stephen J. Kohut, Alison G P Wakeford, Thomas E. Prisinzano
Publikováno v:
International Journal of Neuropsychopharmacology
Background Synthetic cathinones display overlapping behavioral effects with psychostimulants (e.g., methamphetamine [MA]) and/or entactogens (e.g., 3,4-methylenedioxymethaphetamine [MDMA])—presumably reflecting their dopaminergic and/or serotonergi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b2d321f8f72f031b6ff6f5840528c0d
https://doi.org/10.1093/ijnp/pyab017
https://doi.org/10.1093/ijnp/pyab017
Publikováno v:
J Nat Prod
A novel analogue of psilocybin was produced by hybrid chemoenzymatic synthesis in sufficient quantity to enable bioassay. Utilizing purified 4-hydroxytryptamine kinase from Psilocybe cubensis, chemically synthesized 5-methylpsilocin (2) was enzymatic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::728f3a759d6fcdc879e41010c8ea5810
https://doi.org/10.1021/acs.jnatprod.1c00087
https://doi.org/10.1021/acs.jnatprod.1c00087