Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Alexander M Many"'
Autor:
Alexander M Many, Anthony M C Brown
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e101800 (2014)
The characterization of mammary stem cells, and signals that regulate their behavior, is of central importance in understanding developmental changes in the mammary gland and possibly for targeting stem-like cells in breast cancer. The canonical Wnt/
Externí odkaz:
https://doaj.org/article/03298891e4834cdfa88ecc480256a908
Autor:
Lisha Li, Penelope M.Y. Or, Andrew K Chan, Kin Lok Wong, Yubing Wang, Alexander M. Many, Mingfei Yan, Chi Wai Wong, Ui-Soon Khoo, H Guan
Publikováno v:
Cancer Letters. 430:67-78
Phosphatase and tension homolog (PTEN) is a potent tumor suppressor that possesses a PDZ-binding domain (PDZ-BD) at the end of its carboxyl terminus, whose functions during tumorigenesis remains unclear. Here, we crossed a mouse strain with germline
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59ef893b65f0bfdee83643c07cd03539
https://doi.org/10.1016/j.canlet.2018.05.012
https://doi.org/10.1016/j.canlet.2018.05.012
Autor:
Alexander M. Many, Sonia N. Acharya, Daniel S. Maillet, Oleksandr P. Savytskyy, Christina S. Melki, Miriam E. Zolan
Publikováno v:
Chromosoma. 118:471-486
The Mre11-Rad50-Nbs1 (MRN) complex is required for numerous cellular processes that involve interactions with DNA double-strand breaks. For the majority of these processes, the MRN complex is thought to act as a unit, with each protein aiding the act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a21f6b2bbf907fb9cf80f078ead29e49
https://doi.org/10.1007/s00412-009-0209-5
https://doi.org/10.1007/s00412-009-0209-5
Autor:
Jennifer T. Grubb, Sonia N. Acharya, Felicia M. Kennedy, Miriam E. Zolan, Daniel S. Maillet, John A. Tainer, Alexander M. Many, Martina Celerin, R. Scott Williams, Gabriel Moncalián, Andrew P. Schroeder, Jack A. Vincent, Oleksandr P. Savytskyy, Megan A. Greischar, Elizabeth A. Friedle, Heather J. Palmerini
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
El pdf del artículo es la versión pre-print.-- et al.
The Mre11/Rad50/Nbs1 (MRN) complex is required for eukaryotic DNA double-strand break (DSB) repair and meiotic recombination. We cloned the Coprinus cinereus rad50 gene and showed that it c
The Mre11/Rad50/Nbs1 (MRN) complex is required for eukaryotic DNA double-strand break (DSB) repair and meiotic recombination. We cloned the Coprinus cinereus rad50 gene and showed that it c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62219bfb220f6a7f5de917a9c0044a42
https://doi.org/10.1534/genetics.108.092775
https://doi.org/10.1534/genetics.108.092775
Publikováno v:
Cancer Research. 77:1539-1539
PTEN (Phosphatase and tensin homolog) functions as a key negative regulator of PI3K-Akt pathway through its lipid phosphatase activity. Mutations or loss of PTEN is frequently observed in brain, breast, prostate and endometrial cancer. PTEN possesses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9b1f21ade6b2735b4c7b3657c3a4a3f
https://doi.org/10.1158/1538-7445.am2017-1539
https://doi.org/10.1158/1538-7445.am2017-1539
Autor:
Anthony M. C. Brown, Alexander M. Many
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e101800 (2014)
PLoS ONE
PLoS ONE
The characterization of mammary stem cells, and signals that regulate their behavior, is of central importance in understanding developmental changes in the mammary gland and possibly for targeting stem-like cells in breast cancer. The canonical Wnt/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd41054ba688c4d010a747cf1fc4f976
https://doi.org/10.1371/journal.pone.0101800
https://doi.org/10.1371/journal.pone.0101800
Autor:
Anthony M. C. Brown, Alexander M. Many
Publikováno v:
Breast Cancer Research : BCR
The likely roles of Wnt signaling in regulating mammary stem cell behavior have been much discussed, in part because they may underlie the oncogenic effects of Wnt signaling in mammary tissue. Two recent papers add important data to this field. One t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81bbfdd8707922a0274329ba046ffdeb
http://europepmc.org/articles/PMC3096951
http://europepmc.org/articles/PMC3096951