Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Alexander M A van der Wiel"'
Autor:
Alexander M. A. van der Wiel, Lesley Schuitmaker, Ying Cong, Jan Theys, Arne Van Hoeck, Conchita Vens, Philippe Lambin, Ala Yaromina, Ludwig J. Dubois
Publikováno v:
Cancers. 14(17)
Homologous recombination deficiency (HRD) is a prevalent in approximately 17% of tumors and is associated with enhanced sensitivity to anticancer therapies inducing double-strand DNA breaks. Accurate detection of HRD would therefore allow improved pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a96e8d9e4156c87a862c6cba53b6b54b
https://doi.org/10.3390/cancers14174157
https://doi.org/10.3390/cancers14174157
Autor:
Damiënne Marcus, Evert J. Van Limbergen, Philippe Lambin, Alexander M A van der Wiel, Relinde I Y Lieverse, Ludwig Dubois, Ala Yaromina, Jan Theys
Publikováno v:
Molecular Oncology
Molecular Oncology, Vol 14, Iss 7, Pp 1555-1568 (2020)
Molecular Oncology, Vol 14, Iss 7, Pp 1555-1568 (2020)
The extracellular matrix protein fibronectin contains a domain that is rarely found in healthy adults and is almost exclusively expressed by newly formed blood vessels in tumours, particularly in solid tumours, different types of lymphoma and some le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c56fab28b1cc5b61f66cb1995bab648b
http://europepmc.org/articles/PMC7332215
http://europepmc.org/articles/PMC7332215
Autor:
Arthur Jochems, Jeff B. Smaill, Christopher P. Guise, Arne Heyerick, Maria R. Abbattista, Sophie Thiolloy, Amir Ashoorzadeh, Alexander M A van der Wiel, Kevin O. Hicks, Jan Theys, Ludwig Dubois, Philippe Lambin, Xiaojing Lin, Emily Liu, Robert F. Anderson, Zhe Fu, Damiënne Marcus, Victoria Jackson-Patel, Adam V. Patterson, Sisira Kumara, Ala Yaromina, Matthew Bull, Silvia Balbo, Morwena J. Solivio, R. Biemans, Sofie Deschoemaeker, Raymon Niemans, Alexandra M. Mowday, Natasja G. Lieuwes
Publikováno v:
Molecular Cancer Therapeutics, 20(12), 2372-2383. American Association for Cancer Research Inc.
Background Hypoxia-activated prodrugs (HAPs) are a promising class of antineoplastic agents that can selectively eliminate hypoxic tumor cells. The present study evaluates the hypoxia-selectivity and antitumor activity of CP-506, a DNA alkylating HAP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8da436b0cdc3474a21aab13146be81dd
https://pubmed.ncbi.nlm.nih.gov/34625504
https://pubmed.ncbi.nlm.nih.gov/34625504
Autor:
Ludwig Dubois, Jan Theys, Dario Neri, Natasja G. Lieuwes, Alexander M A van der Wiel, Ala Yaromina, R. Biemans, Veronica Olivo Pimentel, Relinde I Y Lieverse, Philippe Lambin, Damiënne Marcus
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 3 (2021)
Journal for ImmunoTherapy of Cancer, 9 (3)
Journal for ImmunoTherapy of Cancer, 9(3):001764. BioMed Central Ltd
Journal for ImmunoTherapy of Cancer
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, 9 (3)
Journal for ImmunoTherapy of Cancer, 9(3):001764. BioMed Central Ltd
Journal for ImmunoTherapy of Cancer
Journal for Immunotherapy of Cancer
BackgroundPoorly immunogenic tumors are hardly responsive to immunotherapies such as immune checkpoint blockade (ICB) and are, therefore, a therapeutic challenge. Combination with other immunotherapies and/or immunogenic therapies, such as radiothera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bae4375d17de5a2aca6741c0b19a0e56
https://jitc.bmj.com/content/9/3/e001764.full
https://jitc.bmj.com/content/9/3/e001764.full
Autor:
Jan Theys, Damiënne Marcus, Sergey Primakov, Ala Yaromina, Philippe Lambin, Ludwig Dubois, Guangyao Wu, Abdalla Ibrahim, Alexander M A van der Wiel, Relinde I Y Lieverse, Sebastian Sanduleanu
Publikováno v:
Cancers
Cancers, Vol 12, Iss 1322, p 1322 (2020)
Cancers, Vol 12, Iss 1322, p 1322 (2020)
Hypoxia—a common feature of the majority of solid tumors—is a negative prognostic factor, as it is associated with invasion, metastasis and therapy resistance. To date, a variety of methods are available for the assessment of tumor hypoxia, inclu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30824910f8b9aa65503cfdcf3cf34569
https://doi.org/10.3390/cancers12051322
https://doi.org/10.3390/cancers12051322