Výsledky vyhledávání - "Alexander M, Walker"

The acute effects of azithromycin use on cardiovascular mortality as compared with amoxicillin–clavulanate in US Veterans

Autor: Maral, DerSarkissian, Yinong, Young-Xu, Mei Sheng, Duh, Rachel H, Bhak, Niki, Palmetto, Eric, Mortensen, Antonio, Anzueto, Catherine, Nguyen, Mu, Cheng, Vera, Frajzyngier, Suna, Park, Angela, Lax, Lisa B, Weatherby, Alexander M, Walker

Publikováno v: Pharmacoepidemiology and Drug Safety. 31:840-850

Azithromycin is a common first-line antibiotic for respiratory infection; however, there is conflicting evidence regarding risk of cardiovascular death. We assessed cardiovascular and noncardiovascular mortality associated with azithromycin versus am

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::632aa70e682ce3b8da93b9c7ae10de20
https://doi.org/10.1002/pds.5451

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Antibiotic prescribing patterns among patients admitted to an academic teaching hospital for COVID-19 during the first wave of the pandemic in Toronto: A retrospective, controlled study

Autor: Miranda So, Andrew M Morris, Alexander M Walker

Publikováno v: J Assoc Med Microbiol Infect Dis Can

Empirical antibiotics are not recommended for coronavirus disease 2019 (COVID-19).In this retrospective study, patients admitted to Toronto General Hospital's general internal medicine from the emergency department for COVID-19 between March 1 and Au

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1df28b6ba452f5b9312be268219ad28
https://doi.org/10.3138/jammi-2021-0020

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Complementary hypotheses in safety surveillance

Autor: Alexander M. Walker

Publikováno v: Sequential Analysis. 39:417-430

Postmarketing safety surveillance studies address two actionable questions: (1) Is the test product riskier than a standard? (2) Is the risk associated with the test product within some tolerable m...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9ee2f6f78cc1cf79c76ecf04c61da474
https://doi.org/10.1080/07474946.2020.1823195

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An Evaluation of the Effect of the OxyContin Reformulation on Unintentional Fatal and Nonfatal Overdose

Autor: Daniel C. Beachler, Kelsey Hall, Renu Garg, Geetanjoli Banerjee, Ling Li, Luke Boulanger, Huseyin Yuce, Alexander M. Walker

Publikováno v: The Clinical journal of pain. 38(6)

OxyContin was reformulated with a polyethylene oxide matrix in August 2010 to reduce the potential for intravenous abuse and for abuse by insufflation. The objective of this study was to evaluate the impact of OxyContin's reformulation on overdose (O

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57b5b90c4580a6962405746a165a0921
https://pubmed.ncbi.nlm.nih.gov/35356897

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Trends of HIV Mortality between 2001 and 2018: An Observational Analysis

Autor: Kripa Patel, Alexander M. Walker, Justin D. Salciccioli, Harpreet Singh, Conor P. Crowley, Joseph Shalhoub, Dominic C Marshall, Omar Al Omari, Richard Goodall, Arashdeep Rupal, Chinmay Jani

Publikováno v: Tropical Medicine and Infectious Disease
Tropical Medicine and Infectious Disease, Vol 6, Iss 173, p 173 (2021)
Tropical Medicine and Infectious Disease; Volume 6; Issue 4; Pages: 173

Since the beginning of the epidemic in the early 1980s, HIV-related illnesses have led to the deaths of over 32.7 million individuals. The objective of this study was to describe current mortality rates for HIV through an observational analysis of HI

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c08d905e8640af6016299dad4e82c79
http://europepmc.org/articles/PMC8544718

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Long-term risk of hepatocellular carcinoma mortality in 23220 hospitalized patients treated with micafungin or other parenteral antifungals

Autor: Francisco M. Marty, Marissa B. Wilck, Mindy G. Schuster, Alexander M. Walker, Christy Varughese, Shmuel Shoham, Alicia Galar, Sebastian Schneeweiss, Maryann Najdzinowicz, Jerod Nagel, Melissa Saul, Melissa D. Johnson, Alyssa R. Letourneau, Fernanda P. Silveira, Joop van Oene, Lisa B. Weatherby, Kausik Datta, Peggy L. Carver

Publikováno v: Journal of Antimicrobial Chemotherapy. 75:221-228

Background Liver tumours observed in rats exposed to micafungin led to a black box warning upon approval in Europe in 2008. Micafungin’s risk for liver carcinogenicity in humans has not been investigated. We sought to describe the risk of fatal hep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a16876833a79e76753741ce6e7e0a038
https://doi.org/10.1093/jac/dkz396

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Structural and Functional Characterization of Dynamic Oligomerization in Burkholderia cenocepacia HMG-CoA Reductase

Autor: Chad W. Hicks, Alexander M. Walker, Samuel W. A. Stewart, Jean-Claude Abboud, Kevin M. Lewis, ChulHee Kang, Riley B. Peacock, Jeffrey M. Watson, Sophia M. Dewing

Publikováno v: Biochemistry. 58:3960-3970

The enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase (HMGR), in most organisms, catalyzes the four-electron reduction of the thioester (S)-HMG-CoA to the primary alcohol (R)-mevalon...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cd973cae29379fe68db97dca5d43fe4b
https://doi.org/10.1021/acs.biochem.9b00494

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Information on doctor and pharmacy shopping for opioids adds little to the identification of presumptive opioid abuse disorders in health insurance claims data

Autor: Lisa B. Weatherby, M. Soledad Cepeda, Daniel C Bradford, Alexander M. Walker

Publikováno v: Substance Abuse and Rehabilitation

Alexander M Walker,1 Lisa B Weatherby,1 M Soledad Cepeda,2 Daniel C Bradford3 1World Health Information Science Consultants, Dedham, MA, USA; 2Janssen Research and Development, Titusville, NJ, USA; 3Advanced Analytics, IQVIA, Plymouth Meeting, PA, US

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::468d739897f1ec79738e045926132f81
http://europepmc.org/articles/PMC6682178

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Pomalidomide induced lupus type hypersensitivity reaction

Autor: Arashdeep Rupal, Carmen M. Perrino, Harpreet Singh, Prudence Lam, Thomas Caughey, Chinmay Jani, Alexander M. Walker

Publikováno v: Current Problems in Cancer: Case Reports, Vol 3, Iss, Pp 100065-(2021)

Multiple myeloma (MM) is a plasma cell disease characterized by a clonal proliferation of malignant plasma cells. Pomalidomide, a novel immunomodulating imide drug (IMiD), prolongs survival in relapsed or refractory cases. Cutaneous toxicity is one o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f82873c9aa71aba42c5917ae4a46401
http://www.sciencedirect.com/science/article/pii/S2666621921000144

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