Characterisation of a nucleo-adhesome

Autor: Alex von Kriegsheim, Linda Kogerman, Bryan Serrels, Niamh McGivern, Alexander Loftus, Valerie G. Brunton, Billie Georgina Cooper Griffith, Emma S. Koeleman, Graeme R. Grimes, Ana Herrero, John C. Dawson, Jayne Culley, Adam Byron, Margaret C. Frame

In addition to central functions in cell adhesion signalling, integrin-associated proteins have wider roles at sites distal to adhesion receptors. In experimentally defined adhesomes, we noticed that there is clear enrichment of proteins that localis

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8eeb54127bc4b815039464d35ac0fe22
https://doi.org/10.1101/2021.08.31.458428

The autophagy protein Ambra1 regulates gene expression by supporting novel transcriptional complexes

Autor: Alexander Loftus, Alex von Kriegsheim, Jimi Wills, Alison F. Munro, Billie Georgina Cooper Griffith, Adam Byron, Christina Schoenherr, Margaret C. Frame

Publikováno v: J Biol Chem
Schoenherr, C, Byron, A, Griffith, B, Loftus, A, Wills, J C, Munro, A F, Von Kriegsheim, A & Frame, M C 2020, ' The autophagy protein Ambra1 regulates gene expression by supporting novel transcriptional complexes ', Journal of Biological Chemistry, pp. jbc.RA120.012565 . https://doi.org/10.1074/jbc.RA120.012565
Schoenherr, C, Byron, A, Griffith, B G C, Loftus, A E P, Wills, J C, Munro, A F, von Kriegsheim, A & Frame, M C 2020, ' The autophagy protein Ambra1 regulates gene expression by supporting novel transcriptional complexes ', Journal of Biological Chemistry, vol. 295, no. 34, pp. 12045-12057 . https://doi.org/10.1074/jbc.RA120.012565

Ambra1 is considered an autophagy and trafficking protein with roles in neurogenesis and cancer cell invasion. Here, we report that Ambra1 also localizes to the nucleus of cancer cells, where it has a novel nuclear scaffolding function that controls

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e78bd97cfd53fdd8c2edaef1ab5c3889
https://pubmed.ncbi.nlm.nih.gov/32616651

Osteoblast-Derived Extracellular Vesicles Are Biological Tools for the Delivery of Active Molecules to Bone

Autor: Anna Teti, Alexander Loftus, Antonio Maurizi, Alfredo Cappariello, Nadia Rucci, Maurizio Muraca

Publikováno v: Journal of Bone and Mineral Research. 33:517-533

Extracellular vesicles (EVs) are newly appreciated regulators of tissue homeostasis and a means of intercellular communication. Reports have investigated the role of EVs and their cargoes in cellular regulation and have tried to fine-tune their biote

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7e02ff5687c9033e7243eb5ff5c5b745
https://doi.org/10.1002/jbmr.3332

Rural veterinary practice in Western Australia 1964 to 2007

Autor: Maxwell, John Alexander Loftus

Publikováno v: Maxwell, John Alexander Loftus (2008) Rural veterinary practice in Western Australia 1964 to 2007. PhD thesis, Murdoch University.

Concern for the plight of rural veterinary practice in Australia existed throughout the 20th century. During the 1970s, the profession highlighted the problems faced by rural practitioners and in 2003, the Frawley Review examined current rural veteri

Externí odkaz: http://researchrepository.murdoch.edu.au/428/

Rural veterinary practice in Western Australia 1964 to 2007

Autor: jmaxwell@katel.net.au, John Alexander Loftus Maxwell

Concern for the plight of rural veterinary practice in Australia existed throughout the 20th century. During the 1970s, the profession highlighted the problems faced by rural practitioners and in 2003, the Frawley Review examined current rural veteri

Externí odkaz: http://wwwlib.murdoch.edu.au/adt/browse/view/adt-MU20081113.142241