Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Alexander Leunig"'
Autor:
Adaya Weissler-Snir, MD, MSc, Sara Saberi, MD, Timothy C. Wong, MD, Antonis Pantazis, MD, Anjali Owens, MD, Alexander Leunig, MD, Chikezie Alvarez, MD, Florian Rader, MD, MSc
Publikováno v:
JACC: Advances, Vol 3, Iss 9, Pp 101210- (2024)
Atrial fibrillation (AF) is common among patients with hypertrophic cardiomyopathy (HCM) with a prevalence greater than 25%. AF in HCM is associated with a high risk of stroke and can be a marker of more advanced cardiomyopathy. Although, it frequent
Externí odkaz:
https://doaj.org/article/2b796dea66af4a64a9653d0a789eaf00
Autor:
Tabea M. Eser, Olga Baranov, Manuel Huth, Mohammed I. M. Ahmed, Flora Deák, Kathrin Held, Luming Lin, Kami Pekayvaz, Alexander Leunig, Leo Nicolai, Georgios Pollakis, Marcus Buggert, David A. Price, Raquel Rubio-Acero, Jakob Reich, Philine Falk, Alissa Markgraf, Kerstin Puchinger, Noemi Castelletti, Laura Olbrich, Kanika Vanshylla, Florian Klein, Andreas Wieser, Jan Hasenauer, Inge Kroidl, Michael Hoelscher, Christof Geldmacher
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Despite intensive research since the emergence of SARS-CoV-2, it has remained unclear precisely which components of the early immune response protect against the development of severe COVID-19. Here, we perform a comprehensive immunogenetic
Externí odkaz:
https://doaj.org/article/4dc5d871135c41fe9339d69cb0120fce
Autor:
Leo Nicolai, Karin Schiefelbein, Silvia Lipsky, Alexander Leunig, Marie Hoffknecht, Kami Pekayvaz, Ben Raude, Charlotte Marx, Andreas Ehrlich, Joachim Pircher, Zhe Zhang, Inas Saleh, Anna-Kristina Marel, Achim Löf, Tobias Petzold, Michael Lorenz, Konstantin Stark, Robert Pick, Gerhild Rosenberger, Ludwig Weckbach, Bernd Uhl, Sheng Xia, Christoph Andreas Reichel, Barbara Walzog, Christian Schulz, Vanessa Zheden, Markus Bender, Rong Li, Steffen Massberg, Florian Gaertner
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-4 (2022)
Externí odkaz:
https://doaj.org/article/ed292487695f4934991736364329901e
Autor:
Kami Pekayvaz, Alexander Leunig, Rainer Kaiser, Markus Joppich, Sophia Brambs, Aleksandar Janjic, Oliver Popp, Daniel Nixdorf, Valeria Fumagalli, Nora Schmidt, Vivien Polewka, Afra Anjum, Viktoria Knottenberg, Luke Eivers, Lucas E. Wange, Christoph Gold, Marieluise Kirchner, Maximilian Muenchhoff, Johannes C. Hellmuth, Clemens Scherer, Raquel Rubio-Acero, Tabea Eser, Flora Deák, Kerstin Puchinger, Niklas Kuhl, Andreas Linder, Kathrin Saar, Lukas Tomas, Christian Schulz, Andreas Wieser, Wolfgang Enard, Inge Kroidl, Christof Geldmacher, Michael von Bergwelt-Baildon, Oliver T. Keppler, Mathias Munschauer, Matteo Iannacone, Ralf Zimmer, Philipp Mertins, Norbert Hubner, Michael Hoelscher, Steffen Massberg, Konstantin Stark, Leo Nicolai
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-21 (2022)
Infection with SARS-COV-2 can result in self-limited upper airway infection or progress to a more systemic inflammatory condition including pneumonic COVID-19. Here the authors utilise a multi-omics approach to interrogate the immune response of pati
Externí odkaz:
https://doaj.org/article/25f8c8382ab44535bbd9a714a216c8f8
Autor:
Leo Nicolai, Karin Schiefelbein, Silvia Lipsky, Alexander Leunig, Marie Hoffknecht, Kami Pekayvaz, Ben Raude, Charlotte Marx, Andreas Ehrlich, Joachim Pircher, Zhe Zhang, Inas Saleh, Anna-Kristina Marel, Achim Löf, Tobias Petzold, Michael Lorenz, Konstantin Stark, Robert Pick, Gerhild Rosenberger, Ludwig Weckbach, Bernd Uhl, Sheng Xia, Christoph Andreas Reichel, Barbara Walzog, Christian Schulz, Vanessa Zheden, Markus Bender, Rong Li, Steffen Massberg, Florian Gaertner
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
Breakdown of vascular barriers is a major complication of inflammatory diseases. However, the mechanisms underlying platelet recruitment to inflammatory micro-environments remains unclear. Here, the authors identify haptotaxis as a key effector funct
Externí odkaz:
https://doaj.org/article/4823a6cec2a1460586e33e31ba7a0aef
Autor:
Leo Nicolai, Rainer Kaiser, Raphael Escaig, Marie-Louise Hoffknecht, Afra Anjum, Alexander Leunig, Joachim Pircher, Andreas Ehrlich, Michael Lorenz, Hellen Ishikawa-Ankerhold, William C. Aird, Steffen Massberg, Florian Gaertner
Publikováno v:
Haematologica, Vol 107, Iss 7 (2021)
Visualizing cell behavior and effector function on a single cell level has been crucial for understanding key aspects of mammalian biology. Due to their small size, large number and rapid recruitment into thrombi, there is a lack of data on fate and
Externí odkaz:
https://doaj.org/article/43e3282e3a9f488895e15ffcec411f2e
Autor:
Rainer Kaiser, Alexander Leunig, Kami Pekayvaz, Oliver Popp, Markus Joppich, Vivien Polewka, Raphael Escaig, Afra Anjum, Marie-Louise Hoffknecht, Christoph Gold, Sophia Brambs, Anouk Engel, Sven Stockhausen, Viktoria Knottenberg, Anna Titova, Mohamed Haji, Clemens Scherer, Maximilian Muenchhoff, Johannes C. Hellmuth, Kathrin Saar, Benjamin Schubert, Anne Hilgendorff, Christian Schulz, Stefan Kääb, Ralf Zimmer, Norbert Hübner, Steffen Massberg, Philipp Mertins, Leo Nicolai, Konstantin Stark
Publikováno v:
JCI Insight, Vol 6, Iss 18 (2021)
Neutrophils provide a critical line of defense in immune responses to various pathogens, inflicting self-damage upon transition to a hyperactivated, procoagulant state. Recent work has highlighted proinflammatory neutrophil phenotypes contributing to
Externí odkaz:
https://doaj.org/article/6c76effe0be0417985fb0f08c49e4b8c
Autor:
Kami Pekayvaz, Alexander Leunig, Rainer Kaiser, Markus Joppich, Sophia Brambs, Aleksandar Janjic, Oliver Popp, Daniel Nixdorf, Valeria Fumagalli, Nora Schmidt, Vivien Polewka, Afra Anjum, Viktoria Knottenberg, Luke Eivers, Lucas E. Wange, Christoph Gold, Marieluise Kirchner, Maximilian Muenchhoff, Johannes C. Hellmuth, Clemens Scherer, Raquel Rubio-Acero, Tabea Eser, Flora Deák, Kerstin Puchinger, Niklas Kuhl, Andreas Linder, Kathrin Saar, Lukas Tomas, Christian Schulz, Andreas Wieser, Wolfgang Enard, Inge Kroidl, Christof Geldmacher, Michael von Bergwelt-Baildon, Oliver T. Keppler, Mathias Munschauer, Matteo Iannacone, Ralf Zimmer, Philipp Mertins, Norbert Hubner, Michael Hoelscher, Steffen Massberg, Konstantin Stark, Leo Nicolai
Publikováno v:
Nature Communications
The antiviral immune response to SARS-CoV-2 infection can limit viral spread and prevent development of pneumonic COVID-19. However, the protective immunological response associated with successful viral containment in the upper airways remains uncle
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6868e3511307cae2a86591340303a260
https://pubmed.ncbi.nlm.nih.gov/35197461
https://pubmed.ncbi.nlm.nih.gov/35197461
Autor:
Karsten Spiekermann, Konstantin Stark, Raphael Escaig, Steffen Massberg, Anna Titova, Alexander Leunig, Vivien Polewka, Dario Rossaro, Leo Nicolai, Luke Eivers, Afra Anjum, Marie-Louise Hoffknecht, Rainer Kaiser, Kami Pekayvaz, Eva Riedlinger, Matteo Iannacone
Summary paragraphVaccines against SARS-CoV-2 are based on a range of novel vaccine platforms, with adenovirus-based approaches (like ChAdOx1 nCov-19) being one of them. Recently a rare and novel complication of SARS-CoV-2 targeted adenovirus vaccines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e087e8559e1b50438b17dff51547bb57
https://doi.org/10.1101/2021.06.29.450356
https://doi.org/10.1101/2021.06.29.450356
Autor:
Inge Kroidl, Kathrin Saar, Clemens Scherer, Norbert Huebner, Christoph Gold, Maximilian Muenchhoff, Vivien Polewka, Flora Deak, Rainer Kaiser, Wolfgang Enard, Oliver T. Keppler, Alexander Leunig, Leo Nicolai, Christof Geldmacher, Sophia Brambs, Aleksandar Janjic, Lukas Tomas, Lucas E. Wange, Johannes C. Hellmuth, Christian Schulz, Niklas Kuhl, Ralf Zimmer, Andreas Linder, Michael Hölscher, Philip Mertins, Kami Pekayvaz, Michael von Bergwelt-Baildon, Tabea M. Eser, Steffen Massberg, Markus Joppich, Oliver Popp, Konstantin Stark, Marieluise Kirchner
The immune system of most SARS-CoV-2 infected individuals limits viral spread to the upper airways without pulmonary involvement. This prevents the development of pneumonic COVID-19. However, the protective immunological responses causative of succes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35f8ba15243adaf52679a241adad6b85
https://doi.org/10.1101/2021.02.03.429351
https://doi.org/10.1101/2021.02.03.429351