Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Alexander Lagunov"'
Autor:
Yihe Wang, Jason Riordon, Tian Kong, Yi Xu, Brian Nguyen, Junjie Zhong, Jae Bem You, Alexander Lagunov, Thomas G. Hannam, Keith Jarvi, David Sinton
Publikováno v:
Advanced Science, Vol 6, Iss 15, Pp n/a-n/a (2019)
Abstract Intracytoplasmic sperm injection is a popular form of in vitro fertilization, where single sperm are selected by a clinician and injected into an egg. Whereas clinicians employ general morphology‐based guidelines to select the healthiest
Externí odkaz:
https://doaj.org/article/3b870aca151e47599cb8cf329f5e5b41
Autor:
David Sinton, Sa Xiao, Alexander Lagunov, Mohammad Simchi, Thomas Hannam, Keith Jarvi, Reza Nosrati, Jason Riordon
Publikováno v:
Lab on a Chip. 21:775-783
The selection of high quality sperm is critical for intracytoplasmic sperm injection (ICSI), a prevalent assisted reproduction technology. However, standard selection methods are time-consuming and fail to recover the most viable sperm, thereby limit
Autor:
Francesc Bellaubi, Alexander Lagunov
Publikováno v:
Human Ecology. 48:599-608
We describe what we term a “geoethical dilemma” around Lake Turgoyak (Southern Urals, Russia) utilizing semi-structured interviews, oral stories, field visits and a literature review. Lake Turgoyak is a protected natural monument and a place sacr
Autor:
David Sinton, Reza Nosrati, Jason Riordon, Thomas Hannam, Sa Xiao, Keith Jarvi, Yihe Wang, Mohammad Simchi, Jae Bem You, Alexander Lagunov
Publikováno v:
Lab on a chip. 21(12)
Sperm selection is essential for successful fertilization and embryo development. Current clinical sperm selection methods are labor-intensive and lack the selectivity required to isolate high-quality sperm. Microfluidic sperm selection approaches ha
Autor:
David Sinton, Yihe Wang, Biao Zhang, Farhang Tarlan, Thomas Hannam, Keith Jarvi, Percival J. Graham, Jae Bem You, Alexander Lagunov, Jason Riordon, Tian Kong
Publikováno v:
Lab on a Chip. 19:2161-2167
Selection of high-quality sperm is critical to the success of assisted reproductive technologies. Clinical screening for top sperm has long focused on sperm swimming ability when following boundaries or when fully free of constraints. In this work, w
Autor:
Biao Zhang, Reza Nosrati, David Sinton, Thomas Hannam, Keith Jarvi, Carlos Escobedo, Alexander Lagunov, Percival J. Graham, Jason Riordon
Publikováno v:
Nature Reviews Urology. 14:707-730
Infertility is a growing global health issue with far-reaching socioeconomic implications. A downward trend in male fertility highlights the acute need for affordable and accessible diagnosis and treatment. Assisted reproductive technologies are effe
Autor:
David Sinton, Yihe Wang, Jae Bem You, Jason Riordon, Alexander Lagunov, Brian Nguyen, Tian Kong, Junjie Zhong, Thomas Hannam, Keith Jarvi, Yi Xu
Publikováno v:
Advanced Science, Vol 6, Iss 15, Pp n/a-n/a (2019)
Advanced Science
Advanced Science
Intracytoplasmic sperm injection is a popular form of in vitro fertilization, where single sperm are selected by a clinician and injected into an egg. Whereas clinicians employ general morphology‐based guidelines to select the healthiest‐looking
Autor:
Yihe Wang, Scott Sanner, Jason Riordon, David Sinton, Thomas Hannam, Christopher McCallum, Jae Bem You, Alexander Lagunov, Tian Kong, Keith Jarvi
Publikováno v:
Communications Biology, Vol 2, Iss 1, Pp 1-10 (2019)
Communications Biology
Communications Biology
Despite the importance of sperm DNA to human reproduction, currently no method exists to assess individual sperm DNA quality prior to clinical selection. Traditionally, skilled clinicians select sperm based on a variety of morphological and motility
Publikováno v:
Fertility and Sterility. 114:e139
Autor:
Yihe Wang, Thomas Hannam, David Sinton, Christopher McCallum, Jae Bem You, Alexander Lagunov, Farhang Tarlan, Keith Jarvi
Publikováno v:
Lab on a chip. 19(5)
There is a growing appreciation and understanding of cell-to-cell variability in biological samples. However, research and clinical practice in male fertility has relied on population, or sample-based characteristics. Single-cell resolution is partic