Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Alexander L. Weis"'
Autor:
Alexander L. Weis, Veena Prasad, I-Tien Yeh, Asok Banerjee, John C. Lee, Richard F. Ludueña, Lee Chuan C Yeh, Tamas Bakos, Jack A. Tuszynski
Publikováno v:
Investigational New Drugs. 34:129-137
The subunit protein of microtubules is tubulin, which has been the target for some of the most successful and widely used anti-tumor drugs. Most of the drugs that target tubulin bind to the β subunit. There are many isotypes of β-tubulin and their
Autor:
John Torin Huzil, Sambasivarao Damaraju, Richard F. Ludueña, Lorelei Johnson, Tamas Bakos, Alexander L. Weis, Asok Banerjee, Jack A. Tuszynski, Philip Winter
Publikováno v:
Chemical Biology & Drug Design. 75:541-550
Microtubules are the primary target for many anti-cancer drugs, the majority of which bind specifically to beta-tubulin. The existence of several beta-tubulin isotypes, coupled with their varied expression in normal and cancerous cells provides a pla
Publikováno v:
Journal of Photochemistry and Photobiology A: Chemistry. 163:45-51
A nitronyl nitroxide radical covalently linked to an organic fluorophore, pyrene, was synthesized and used to detect superoxide radicals and to quantitatively estimate the antioxidant activity of biological compounds in a wide range of antioxidant re
Autor:
Alexander L. Weis
Publikováno v:
Chemistry and Physics of Lipids. 102:3-12
Enormous progress in the asymmetric synthesis of stereochemically and chemically pure D-erythro-sphingosine and ceramides led to the development of a practical, efficient, easily scaleable process to provide industrial quantities of chiral sphingosin
Autor:
Alexander L. Weis, Solomon P. Wasser
Publikováno v:
International Journal of Medicinal Mushrooms. 1:351-370
Autor:
Nadezda Yu. Mitropolskaya, Asja S. Buchalo, Andrey Ph. Grigansky, Elena L. Gorovits, Alexander L. Weis, Solomon P. Wasser, Elvira F. Solomko
Publikováno v:
International Journal of Medicinal Mushrooms. 1:93-103
Publikováno v:
Tetrahedron Letters. 40:223-226
A novel series of fluorescent labels containing multiple fluorescein moieties attached to a bridgeheadsubstituted adamantane has been synthesized. Molecules containing two, three or four fluorescein residues were prepared and their fluorescence was m
Autor:
Alexander L. Weis, Solomon P. Wasser
Publikováno v:
International Journal of Medicinal Mushrooms. 1:31-62
Publikováno v:
ChemInform. 30
The synthesis and conversion of a new spermidine equivalent ( 2 ) to squalamine is reported. It is prepared in a practical manner, is stable to sodium borohydride reduction, is converted to spermidine under mild conditions, and is not prone to intern