Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Alexander L. Ticho"'
Autor:
Alison N. McRae, Alexander L. Ticho, Yuanhang Liu, Maria Laura Ricardo-Silgado, Nothando N. Mangena, Fauzi Feris Jassir, Daniel Gonzalez-Izundegui, Gerardo Calderon, Fariborz Rakhshan Rohakhtar, Vernadette Simon, Ying Li, Cadman Leggett, Daniela Hurtado, Nicholas LaRusso, Andres J. Acosta
Publikováno v:
EBioMedicine, Vol 107, Iss , Pp 105283- (2024)
Summary: Background: Gut L-type enteroendocrine cells (EECs) are intestinal chemosensory cells that secrete satiety hormones GLP-1 and PYY in response to activation of G-protein coupled receptors (GPCRs) by luminal components of nutrient digestion an
Externí odkaz:
https://doaj.org/article/c9f0174c06574574b83f30365b0f7ba4
Autor:
Christopher R. Manzella, Max Ackerman, Megha Singhal, Alexander L. Ticho, Justin Ceh, Waddah A. Alrefai, Seema Saksena, Pradeep K. Dudeja, Ravinder K. Gill
Publikováno v:
Cellular Physiology and Biochemistry, Vol 54, Iss 1, Pp 126-141 (2020)
Externí odkaz:
https://doaj.org/article/8e41b12155e94945a0945bf4fc245d2f
Publikováno v:
Liver Research, Vol 3, Iss 1, Pp 31-39 (2019)
Bile acids modulate several gastrointestinal (GI) functions including electrolyte secretion and absorption, gastric emptying, and small intestinal and colonic motility. High concentrations of bile acids lead to diarrhea and are implicated in the deve
Externí odkaz:
https://doaj.org/article/bca3174a44ae41b7b91b4324b84a0c38
Autor:
Seema Saksena, Christopher R. Manzella, Anoop Kumar, David Jarava, Alexander L. Ticho, Waddah A. Alrefai, Ravinder K. Gill, Pooja Malhotra, Pradeep K. Dudeja, Megha Singhal, Nathaniel W Holton
Publikováno v:
Am J Physiol Cell Physiol
The serotonin transporter (SERT) functions to regulate the availability of serotonin (5-HT) in the brain and intestine. An intestine-specific mRNA variant arising from a unique transcription start site and alternative promoter in the SERT gene has be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ca71f9737abe75bd89cef50741840b3
https://doi.org/10.1152/ajpcell.00477.2019
https://doi.org/10.1152/ajpcell.00477.2019
Autor:
Waddah A. Alrefai, Pooja Malhotra, Alexander L. Ticho, Christopher R. Manzella, Seema Saksena, Pradeep K. Dudeja, Ravinder K. Gill
Publikováno v:
J Biol Chem
The ileal apical sodium-dependent bile acid transporter (ASBT) is crucial for the enterohepatic circulation of bile acids. ASBT function is rapidly regulated by several posttranslational modifications. One reversible posttranslational modification is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb387e949ba6237072a6ba2cca2c55c6
https://doi.org/10.1074/jbc.ra119.011032
https://doi.org/10.1074/jbc.ra119.011032
Autor:
Max Ackerman, Waddah A. Alrefai, Megha Singhal, Seema Saksena, Pradeep K. Dudeja, Justin Ceh, Alexander L. Ticho, Christopher R. Manzella, Ravinder K. Gill
Publikováno v:
Cellular Physiology and Biochemistry, Vol 54, Iss 1, Pp 126-141 (2020)
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology
Background/aims Serotonin (5-hydroxytryptamine, 5-HT) is a neurotransmitter and hormone with important physiological functions in many organs, including the intestine. We have previously shown that 5-HT activates the aryl hydrocarbon receptor (AhR) i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f12dec05ea2f0e1ff2dbdddc3f4678f
https://www.cellphysiolbiochem.com/Articles/000209/
https://www.cellphysiolbiochem.com/Articles/000209/
Autor:
Daesung Lee, Seema Saksena, Waddah A. Alrefai, Pradeep K. Dudeja, Pooja Malhotra, Ravinder K. Gill, Arivarasu Natarajan Anbazhagan, Nathan Calzadilla, Hyunjin Lee, Alexander L. Ticho
Publikováno v:
Am J Physiol Cell Physiol
Niemann-Pick C1 Like-1 (NPC1L1) mediates the uptake of micellar cholesterol by intestinal epithelial cells and is the molecular target of the cholesterol-lowering drug ezetimibe (EZE). The detailed mechanisms responsible for intracellular shuttling o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03e337841e077ca5aaa77850663cdae8
https://pubmed.ncbi.nlm.nih.gov/33760662
https://pubmed.ncbi.nlm.nih.gov/33760662
Autor:
Seema Saksena, Pradeep K. Dudeja, Ravinder K. Gill, Daesung Lee, Waddah A. Alrefai, Alexander L. Ticho, Hyunjin Lee
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 315:G529-G537
Bile acid transporters, including the ileal apical sodium-dependent bile acid transporter (ASBT) and the hepatic sodium-taurocholate cotransporting polypeptide (NTCP), are crucial for the enterohepatic circulation of bile acids. Our objective was to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f452550329e7f59683dd2096a248a6db
https://doi.org/10.1152/ajpgi.00133.2018
https://doi.org/10.1152/ajpgi.00133.2018
Publikováno v:
Comprehensive Physiology
The intestinal reclamation of bile acids is crucial for the maintenance of their enterohepatic circulation. The majority of bile acids are actively absorbed via specific transport proteins that are highly expressed in the distal ileum. The uptake of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca2190a90b5a89d183b3766f79873931
https://pubmed.ncbi.nlm.nih.gov/31853951
https://pubmed.ncbi.nlm.nih.gov/31853951
Autor:
Anchal Sharma, Aisha Qazi, Waddah A. Alrefai, Nathan Calzadilla, Seema Saksena, Pooja Malhotra, Alexander L. Ticho, Ravinder K. Gill, Pradeep K. Dudeja
Publikováno v:
Gastroenterology. 160:S-38
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::130e52533bff846756b2446e48b2d5d4
https://doi.org/10.1016/s0016-5085(21)00838-6
https://doi.org/10.1016/s0016-5085(21)00838-6