Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Alexander L. N. van Nuijs"'
Autor:
Andrea Rodríguez-Carrillo, Veerle J. Verheyen, Alexander L. N. Van Nuijs, Mariana F. Fernández, Sylvie Remy
Publikováno v:
Frontiers in Toxicology, Vol 5 (2024)
The present narrative review summarizes recent findings focusing on the role of brain-derived neurotrophic factor (BDNF) as a biomarker of effect for neurodevelopmental alterations during adolescence, based on health effects of exposure to environmen
Externí odkaz:
https://doaj.org/article/da7aedf56df2441b8864a66fbd411df2
Autor:
Rani Robeyns, Angela Sisto, Elias Iturrospe, Katyeny Manuela da Silva, Maria van de Lavoir, Vincent Timmerman, Adrian Covaci, Sigrid Stroobants, Alexander L. N. van Nuijs
Publikováno v:
Metabolites, Vol 14, Iss 5, p 248 (2024)
Torin1, a selective kinase inhibitor targeting the mammalian target of rapamycin (mTOR), remains widely used in autophagy research due to its potent autophagy-inducing abilities, regardless of its unspecific properties. Recognizing the impact of mTOR
Externí odkaz:
https://doaj.org/article/739793a46fab4b7c926ef1fe9f523065
Publikováno v:
BMC Health Services Research, Vol 22, Iss 1, Pp 1-9 (2022)
Abstract Background A longstanding debate exists about including a ‘reason for use’ on prescriptions for medication. Little is known, however, about patients’ opinions on this subject. Methods An internet-based questionnaire, consisting mainly
Externí odkaz:
https://doaj.org/article/ca5ecc0508fa497cb28ec0d7fcbe9f76
Autor:
Samya Van Coillie, Emily Van San, Ines Goetschalckx, Bartosz Wiernicki, Banibrata Mukhopadhyay, Wulf Tonnus, Sze Men Choi, Ria Roelandt, Catalina Dumitrascu, Ludwig Lamberts, Geert Dams, Wannes Weyts, Jelle Huysentruyt, Behrouz Hassannia, Irina Ingold, Suhas Lele, Evelyne Meyer, Maya Berg, Ruth Seurinck, Yvan Saeys, An Vermeulen, Alexander L. N. van Nuijs, Marcus Conrad, Andreas Linkermann, Mohan Rajapurkar, Peter Vandenabeele, Eric Hoste, Koen Augustyns, Tom Vanden Berghe
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Catalytic iron is associated with intensive care unit mortality and is known to cause free radical-mediated cellular toxicity. Here the authors show that a soluble ferrostatin-analogue (a ferroptosis inhibitor) protects mice from injury and death in
Externí odkaz:
https://doaj.org/article/a4909380e98741e3bf0ff690fb71d483
Autor:
Tim Boogaerts, Siel Van den Bogaert, Laura A. E. Van Poelvoorde, Diala El Masri, Naomi De Roeck, Nancy H. C. Roosens, Marie Lesenfants, Lies Lahousse, Koenraad Van Hoorde, Alexander L. N. van Nuijs, Peter Delputte
Publikováno v:
Viruses, Vol 14, Iss 3, p 610 (2022)
Since the beginning of the COVID-19 pandemic, the wastewater-based epidemiology (WBE) of SARS-CoV-2 has been used as a complementary indicator to follow up on the trends in the COVID-19 spread in Belgium and in many other countries. To further develo
Externí odkaz:
https://doaj.org/article/f4844b50236a4da48b6a8bc91478dd66
Autor:
Katyeny Manuela da Silva, Elias Iturrospe, Chloe Bars, Dries Knapen, Steven Van Cruchten, Adrian Covaci, Alexander L. N. van Nuijs
Publikováno v:
Metabolites, Vol 11, Iss 9, p 635 (2021)
Metabolomics has achieved great progress over the last 20 years, and it is currently considered a mature research field. As a result, the number of applications in toxicology, biomarker, and drug discovery has also increased. Toxicometabolomics has e
Externí odkaz:
https://doaj.org/article/e1208cc4edb948aa8980abb96d76fc69
Autor:
Nikita Hanning, Michelle De bruyn, Hannah Ceuleers, Tim Boogaerts, Maya Berg, Annemieke Smet, Heiko U. De Schepper, Jurgen Joossens, Alexander L. N. van Nuijs, Joris G. De Man, Koen Augustyns, Ingrid De Meester, Benedicte Y. De Winter
Publikováno v:
Pharmaceutics, Vol 13, Iss 6, p 811 (2021)
Dysregulation of the protease–antiprotease balance in the gastrointestinal tract has been suggested as a mechanism underlying visceral hypersensitivity in conditions such as inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS). We ai
Externí odkaz:
https://doaj.org/article/bfb9756fc6404ddbabce04e440fd583d
Autor:
Juliet Kinyua, Aikaterini K. Psoma, Nikolaos I. Rousis, Maria-Christina Nika, Adrian Covaci, Alexander L. N. van Nuijs, Νikolaos S. Τhomaidis
Publikováno v:
Metabolites, Vol 11, Iss 2, p 66 (2021)
There is a paucity of information on biotransformation and stability of new psychoactive substances (NPS) in wastewater. Moreover, the fate of NPS and their transformation products (TPs) in wastewater treatment plants is not well understood. In this
Externí odkaz:
https://doaj.org/article/939f7b38efb44efabda3019b3d160e23
Chlorogenic Acid as a Model Compound for Optimization of an In Vitro Gut Microbiome-Metabolism Model
Autor:
Olivier Mortelé, Elias Iturrospe, Annelies Breynaert, Christine Lammens, Xavier Basil Britto, Surbhi Malhotra-Kumar, Philippe Jorens, Luc Pieters, Alexander L. N. van Nuijs, Nina Hermans
Publikováno v:
Proceedings, Vol 11, Iss 1, p 31 (2019)
It has been believed that the metabolism of xenobiotics occurred mainly by the cytochrome P450 enzyme system in the liver. However, recent data clearly suggest a significant role for the gut microbiota in the metabolism of xenobiotic compounds. This
Externí odkaz:
https://doaj.org/article/b5dd254c9fcb4c05bc397f56cae48688
Autor:
Elias Iturrospe, Rani Robeyns, Katyeny Manuela da Silva, Maria van de Lavoir, Joost Boeckmans, Tamara Vanhaecke, Alexander L. N. van Nuijs, Adrian Covaci
Publikováno v:
Archives of toxicology
Despite the high prevalence of alcoholic liver disease, its identification and characterization remain poor, especially in early stages such as alcoholic fatty liver disease and alcoholic steatohepatitis. This latter implies diagnostic difficulties,