Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Alexander L. N. Van Nuijs"'
Autor:
Andrea Rodríguez-Carrillo, Veerle J. Verheyen, Alexander L. N. Van Nuijs, Mariana F. Fernández, Sylvie Remy
Publikováno v:
Frontiers in Toxicology, Vol 5 (2024)
The present narrative review summarizes recent findings focusing on the role of brain-derived neurotrophic factor (BDNF) as a biomarker of effect for neurodevelopmental alterations during adolescence, based on health effects of exposure to environmen
Externí odkaz:
https://doaj.org/article/da7aedf56df2441b8864a66fbd411df2
Autor:
Rani Robeyns, Angela Sisto, Elias Iturrospe, Katyeny Manuela da Silva, Maria van de Lavoir, Vincent Timmerman, Adrian Covaci, Sigrid Stroobants, Alexander L. N. van Nuijs
Publikováno v:
Metabolites, Vol 14, Iss 5, p 248 (2024)
Torin1, a selective kinase inhibitor targeting the mammalian target of rapamycin (mTOR), remains widely used in autophagy research due to its potent autophagy-inducing abilities, regardless of its unspecific properties. Recognizing the impact of mTOR
Externí odkaz:
https://doaj.org/article/739793a46fab4b7c926ef1fe9f523065
Publikováno v:
BMC Health Services Research, Vol 22, Iss 1, Pp 1-9 (2022)
Abstract Background A longstanding debate exists about including a ‘reason for use’ on prescriptions for medication. Little is known, however, about patients’ opinions on this subject. Methods An internet-based questionnaire, consisting mainly
Externí odkaz:
https://doaj.org/article/ca5ecc0508fa497cb28ec0d7fcbe9f76
Autor:
Samya Van Coillie, Emily Van San, Ines Goetschalckx, Bartosz Wiernicki, Banibrata Mukhopadhyay, Wulf Tonnus, Sze Men Choi, Ria Roelandt, Catalina Dumitrascu, Ludwig Lamberts, Geert Dams, Wannes Weyts, Jelle Huysentruyt, Behrouz Hassannia, Irina Ingold, Suhas Lele, Evelyne Meyer, Maya Berg, Ruth Seurinck, Yvan Saeys, An Vermeulen, Alexander L. N. van Nuijs, Marcus Conrad, Andreas Linkermann, Mohan Rajapurkar, Peter Vandenabeele, Eric Hoste, Koen Augustyns, Tom Vanden Berghe
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Catalytic iron is associated with intensive care unit mortality and is known to cause free radical-mediated cellular toxicity. Here the authors show that a soluble ferrostatin-analogue (a ferroptosis inhibitor) protects mice from injury and death in
Externí odkaz:
https://doaj.org/article/a4909380e98741e3bf0ff690fb71d483
Autor:
Karin Hek, Tim Boogaerts, Robert A Verheij, Hans De Loof, Liset van Dijk, Alexander L N van Nuijs, Willemijn M Meijer, Hilde Philips
Publikováno v:
PLoS ONE, Vol 17, Iss 4, p e0265283 (2022)
BackgroundIncreased opioid prescribing has raised concern, as the benefits of pain relief not always outweigh the risks. Acute and chronic pain is often treated in a primary care out-of-hours (OOH) setting. This setting may be a driver of opioid use
Externí odkaz:
https://doaj.org/article/d9ad7080914947238ffbb9a7700798b8
Autor:
Tim Boogaerts, Siel Van den Bogaert, Laura A. E. Van Poelvoorde, Diala El Masri, Naomi De Roeck, Nancy H. C. Roosens, Marie Lesenfants, Lies Lahousse, Koenraad Van Hoorde, Alexander L. N. van Nuijs, Peter Delputte
Publikováno v:
Viruses, Vol 14, Iss 3, p 610 (2022)
Since the beginning of the COVID-19 pandemic, the wastewater-based epidemiology (WBE) of SARS-CoV-2 has been used as a complementary indicator to follow up on the trends in the COVID-19 spread in Belgium and in many other countries. To further develo
Externí odkaz:
https://doaj.org/article/f4844b50236a4da48b6a8bc91478dd66
Autor:
Elias Iturrospe, Rani Robeyns, Katyeny Manuela da Silva, Maria van de Lavoir, Joost Boeckmans, Tamara Vanhaecke, Alexander L. N. van Nuijs, Adrian Covaci
Publikováno v:
Archives of toxicology
Despite the high prevalence of alcoholic liver disease, its identification and characterization remain poor, especially in early stages such as alcoholic fatty liver disease and alcoholic steatohepatitis. This latter implies diagnostic difficulties,
Autor:
Katyeny Manuela da Silva, Elias Iturrospe, Chloe Bars, Dries Knapen, Steven Van Cruchten, Adrian Covaci, Alexander L. N. van Nuijs
Publikováno v:
Metabolites, Vol 11, Iss 9, p 635 (2021)
Metabolomics has achieved great progress over the last 20 years, and it is currently considered a mature research field. As a result, the number of applications in toxicology, biomarker, and drug discovery has also increased. Toxicometabolomics has e
Externí odkaz:
https://doaj.org/article/e1208cc4edb948aa8980abb96d76fc69
Autor:
Celine Gys, Olivier Mortelé, Babette van Rafelghem, Eleanor Berry, Alexander L N van Nuijs, Willy Lambert, Werner Jacobs, Sofie Schouwers, Anissa Meskal, Ellen Van Hemeldonck, Luc Heytens, Hugo Neels, Adrian Covaci
Publikováno v:
Journal of analytical toxicology
Toxicological data on overdose with human immunodeficiency virus inhibitors are scarce. We present a case report of two independent suicide attempts by self-administered overdose with the same antiretroviral medicine Genvoya® (emtricitabine/elvitegr
Autor:
Katyeny Manuela da Silva, Elias Iturrospe, Rik van den Boom, Maria van de Lavoir, Rani Robeyns, Lucia Vergauwen, Dries Knapen, Matthias Cuykx, Adrian Covaci, Alexander L. N. van Nuijs
Publikováno v:
Journal of separation science
Lipidomics analysis of zebrafish tissues has shown promising results to understand disease-related outcomes of exposure to toxic substances at molecular level. However, knowledge about their lipidome is limited, as most untargeted studies only identi