One-Dimensional 13C NMR Is a Simple and Highly Quantitative Method for Enantiodiscrimination

Autor: Peter P. Lankhorst, Jozef H. J. van Rijn, Alexander L. L. Duchateau

Publikováno v: Molecules, Vol 23, Iss 7, p 1785 (2018)

The discrimination of enantiomers of mandelonitrile by means of 1D 13C NMR and with the aid of the chiral solvating agent (S)-(+)-1-(9-anthryl)-2,2,2-trifluoroethanol (TFAE) is presented. 1H NMR fails for this specific compound because proton signals

Externí odkaz: https://doaj.org/article/4ab15325127e40a7bee22be1b6315f0b

Discrimination of stereoisomers by one-dimensional

Autor: Peter P, Lankhorst, Alexander L L, Duchateau, Thomas, Netscher

Publikováno v: Magnetic resonance in chemistry : MRCREFERENCES. 59(11)

All 16 resolved! A vitamin E-derived compound containing four chiral centers is the first example where all stereoisomers, that is, eight diastereomeric pairs of enantiomers, could be discriminated in a single NMR run. Measurement at 176 MHz in the p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1542259b61d37646ad8d0a447d81743d
https://pubmed.ncbi.nlm.nih.gov/34380173

The Crystalline Sponge Method in Water

Autor: Paul Tinnemans, Maarten Honing, René de Gelder, Wester de Poel, Floris P. J. T. Rutjes, Alexander L. L. Duchateau, Elias Vlieg

Publikováno v: Chemistry : a European Journal, 25, pp. 14999-15003
Chemistry : a European Journal, 25, 14999-15003
Chemistry: a European journal, 25(65), 14999-15003. Wiley-VCH Verlag

The crystalline sponge method allows for the elucidation of the (absolute) structure of molecules using single-crystal X-ray diffraction and eliminates the need for crystals of the target compound. An important limitation for the application of the c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::634fb5b6db25cdb5369a14e09f633949
https://cris.maastrichtuniversity.nl/en/publications/e31c4fdc-6a30-479a-93a8-45fbb3bcd190

A Simple13C NMR Method for the Discrimination of Complex Mixtures of Stereoisomers: All Eight Stereoisomers of α-Tocopherol Resolved

Autor: Peter P. Lankhorst, Alexander L. L. Duchateau, Thomas Netscher

Publikováno v: Chirality. 27:850-855

A simple one-dimensional (13)C NMR method is presented to discriminate between stereoisomers of organic compounds with more than one chiral center. By means of this method it is possible to discriminate between all eight stereoisomers of α-tocophero

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a557668399fb7cf31c10fdd1883dbbfc
https://doi.org/10.1002/chir.22535

Racemic and Enantiopure Camphene and Pinene Studied by the Crystalline Sponge Method

Autor: Floris P. J. T. Rutjes, Wester de Poel, Maarten Honing, Paul Tinnemans, Elias Vlieg, René de Gelder, Alexander L. L. Duchateau

Publikováno v: Crystal Growth & Design
Crystal Growth & Design, 18, 126-132
Crystal Growth & Design, 18, 1, pp. 126-132

The use of an achiral metal–organic framework for structure determination of chiral compounds is demonstrated for camphene and pinene. The structure of enantiopure β-pinene can be resolved using the crystalline sponge method. However, α-pinene ca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::296eead96fbce4ce63acf40a810283ba
https://pubmed.ncbi.nlm.nih.gov/29317854