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pro vyhledávání: '"Alexander Lürbke"'
Autor:
Alexander Lürbke, Karin Hagemeier, Qiao-Ling Cui, Imke Metz, Wolfgang Brück, Jack Antel, Tanja Kuhlmann
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e72822 (2013)
Multiple sclerosis is the most frequent demyelinating disease in the human CNS characterized by inflammation, demyelination, relative axonal loss and gliosis. Remyelination occurs, but is frequently absent or restricted to a small remyelinated rim at
Externí odkaz:
https://doaj.org/article/7f48f265fe544222a33556836fbfcc39
Autor:
Karin Hagemeier, Jack Antel J, Luisca Klotz, Wolfgang Brück, Stephanie Hucke, Tanja Kuhlmann, Elke Hoffmann, Stefanie Albrecht, Elena Klassen, Alexander Lürbke, Qiao-Ling Cui, Anna Preisner
Publikováno v:
Glia. 61:1712-1723
The mechanisms involved in oligodendroglial cell death in human demyelinating diseases are only partly understood. Here, we demonstrate that the BH3 only protein Puma, but not Noxa, is essential for oligodendroglial cell death in toxic demyelination
Autor:
Amke Hesse, Wolfgang Brück, Hana Friedman, Alan C. Peterson, Tanja Kuhlmann, Alexander Lürbke, Karin Hagemeier, Jasmin Held
Publikováno v:
Glia. 60:271-280
Oligodendroglial damage and loss are typical characteristics of demyelinating diseases such as multiple sclerosis (MS) and the leukodystrophies. Axonal loss is the underlying cause of permanent neurological deficits in MS and it is thought to arise f
Autor:
Imke Metz, Jack P. Antel, Qiao-Ling Cui, Alexander Lürbke, Tanja Kuhlmann, Karin Hagemeier, Wolfgang Brück
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e72822 (2013)
PLoS ONE
PLoS ONE
Multiple sclerosis is the most frequent demyelinating disease in the human CNS characterized by inflammation, demyelination, relative axonal loss and gliosis. Remyelination occurs, but is frequently absent or restricted to a small remyelinated rim at