Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Alexander Kurze"'
Autor:
Thomas G. Gligoris, Vincenzo Costanzo, Bin Hu, Maria Wissler, Sugako Ogushi, James E Collier, Kim Nasmyth, Johanna C. Scheinost, Alexander Kurze, Menelaos Voulgaris, Madhusudhan Srinivasan, Kok-Lung Chan, Naomi J Petela
Publikováno v:
Cell
Summary As predicted by the notion that sister chromatid cohesion is mediated by entrapment of sister DNAs inside cohesin rings, there is perfect correlation between co-entrapment of circular minichromosomes and sister chromatid cohesion. In most cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd57acd758c4e2ebd0fc1d78dfab2c46
https://doi.org/10.1101/197848
https://doi.org/10.1101/197848
Publikováno v:
Journal of Clinical Oncology. 37:e18557-e18557
e18557 Background: The advent of NGS technologies revolutionized patient management. Compiling a comprehensive list of genomic alterations and summarizing the clinical implications is complex and time-consuming. One main difficulty lies in detecting
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::247d72088f697ec11259169b5d30abd0
https://doi.org/10.1200/jco.2019.37.15_suppl.e18557
https://doi.org/10.1200/jco.2019.37.15_suppl.e18557
Publikováno v:
The EMBO Journal
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Cohesin's Smc1, Smc3, and kleisin subunits create a tripartite ring within which sister DNAs are entrapped. Evidence suggests that DNA enters through a gate created by transient dissociation of the Smc1/3 interface. Release at the onset of anaphase i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19ff1f6416a2200224fa30bada76b37f
https://doi.org/10.1038/emboj.2012.346
https://doi.org/10.1038/emboj.2012.346
Autor:
Takehiko Itoh, Christian H. Haering, Sarah E. Dixon, Ajay Kumar Mishra, Syma Khalid, Katharine A. Michie, Lana Strmecki, Jan Löwe, Katsuhiko Shirahige, Alexander Kurze, Kim Nasmyth
Publikováno v:
The EMBO Journal. 30:364-378
Cohesin's structural maintenance of chromosome 1 (Smc1) and Smc3 are rod-shaped proteins with 50-nm long intra-molecular coiled-coil arms with a heterodimerization domain at one end and an ABC-like nucleotide-binding domain (NBD) at the other. Hetero
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22b427878235a9709e82a24cbf18801e
https://doi.org/10.1038/emboj.2010.315
https://doi.org/10.1038/emboj.2010.315
Autor:
Pelin Uluocak, Ajay Kumar Mishra, Tatsuya Nishino, Jean Metson, Benjamin D. Rowland, Vittorio L. Katis, Maurici B. Roig, Kim Nasmyth, Alexander Kurze, Richard Imre, Frédéric Beckouët, Karl Mechtler, Philippa Underwood
Publikováno v:
Molecular Cell
Molecular Cell, Elsevier, 2009, 33 (6), pp.763-774. ⟨10.1016/j.molcel.2009.02.028⟩
Molecular Cell, Elsevier, 2009, 33 (6), pp.763-774. ⟨10.1016/j.molcel.2009.02.028⟩
Cohesin's Smc1, Smc3, and Scc1 subunits form a tripartite ring that entraps sister DNAs. Scc3, Pds5, and Rad61 (Wapl) are regulatory subunits that control this process. We describe here smc3, scc3, pds5, and rad61 mutations that permit yeast cell pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a6172ffa77409d54cbf2b22f6f38928
Publikováno v:
Nucleic Acids Research
Sequencing DNA fragments associated with proteins following in vivo cross-linking with formaldehyde (known as ChIP-seq) has been used extensively to describe the distribution of proteins across genomes. It is not widely appreciated that this method m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::85074d564f09ad4be6743a5bcc7f2305
https://pubmed.ncbi.nlm.nih.gov/26130708
https://pubmed.ncbi.nlm.nih.gov/26130708
Autor:
Alexander, Kurze, Katharine A, Michie, Sarah E, Dixon, Ajay, Mishra, Takehiko, Itoh, Syma, Khalid, Lana, Strmecki, Katsuhiko, Shirahige, Christian H, Haering, Jan, Löwe, Kim, Nasmyth
Publikováno v:
The EMBO Journal
A positively charged channel within the Smc1/Smc3 hinge required for sister chromatid cohesion DNA has been suggested to enter ring-shaped cohesin complexes via a structural maintenance of chromosome (SMC) protein dimerization interface. Structure-ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b7a942ab99555dcfcf108552b61157fe
https://pubmed.ncbi.nlm.nih.gov/21139566
https://pubmed.ncbi.nlm.nih.gov/21139566
Autor:
Syma Khalid, Katsuhiko Shirahige, Alexander Kurze, Bin Hu, Ana-Maria Farcas, Yuki Katou, Kim Nasmyth, Sarah E. Dixon, Ajay Kumar Mishra, Frédéric Beckouët
Publikováno v:
Current Biology-CB
Current Biology-CB, Elsevier, 2010, 20 (4), pp.279-289. ⟨10.1016/j.cub.2009.12.059⟩
Current Biology
Current Biology-CB, Elsevier, 2010, 20 (4), pp.279-289. ⟨10.1016/j.cub.2009.12.059⟩
Current Biology
Summary Background The cohesin complex that mediates sister chromatid cohesion contains three core subunits: Smc1, Smc3, and Scc1. Heterotypic interactions between Smc1 and Smc3 dimerization domains create stable V-shaped Smc1/Smc3 heterodimers with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::004b1b8802bf62d5fa891868f1252bec
http://ora.ox.ac.uk/objects/uuid:76e837b3-f8d3-4147-a652-c1c251fc4b53
http://ora.ox.ac.uk/objects/uuid:76e837b3-f8d3-4147-a652-c1c251fc4b53