Výsledky vyhledávání - "Alexander Kosyakov"

Comparative sequence analyses of rhodopsin and RPE65 reveal patterns of selective constraint across hereditary retinal disease mutations

Autor: Alexander Kosyakov, Ryan K. Schott, Portia L. Tang, Gianni M Castiglione, Belinda S. W. Chang, Frances E. Hauser, Daniel A. Gow, Alexander Van Nynatten

Publikováno v: Visual neuroscience. 33

Retinitis pigmentosa (RP) comprises several heritable diseases that involve photoreceptor, and ultimately retinal, degeneration. Currently, mutations in over 50 genes have known links to RP. Despite advances in clinical characterization, molecular ch

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67c78598dfd6acfe3d1b196a63e4689a
https://pubmed.ncbi.nlm.nih.gov/26750628

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Spectral Tuning of Killer Whale (Orcinus orca) Rhodopsin: Evidence for Positive Selection and Functional Adaptation in a Cetacean Visual Pigment

Autor: Alexander Kosyakov, Belinda S. W. Chang, Sarah Z. Dungan

Publikováno v: Molecular biology and evolution. 33(2)

Cetaceans have undergone a remarkable evolutionary transition that was accompanied by many sensory adaptations, including modification of the visual system for underwater environments. Recent sequencing of cetacean genomes has made it possible to beg

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd9b179e39638856748b5fdd2cc7d260
https://pubmed.ncbi.nlm.nih.gov/26486871

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