Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Alexander Korn"'
Autor:
Benedikt Schwarze, Alexander Korn, Corinna Höfling, Ulrike Zeitschel, Martin Krueger, Steffen Roßner, Daniel Huster
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract Fibril formation of amyloid β (Aβ) peptides is one of the key molecular events connected to Alzheimer’s disease. The pathway of formation and mechanism of action of Aβ aggregates in biological systems is still object of very active rese
Externí odkaz:
https://doaj.org/article/baa97eb7d29641b28269155211887f4e
Autor:
Jacob Fritzsch, Alexander Korn, Dayana Surendran, Martin Krueger, Holger A. Scheidt, Kaustubh R. Mote, Perunthiruthy K. Madhu, Sudipta Maiti, Daniel Huster
Publikováno v:
Biomolecules, Vol 11, Iss 12, p 1848 (2021)
Amyloid β (Aβ) is a peptide known to form amyloid fibrils in the brain of patients suffering from Alzheimer’s disease. A complete mechanistic understanding how Aβ peptides form neurotoxic assemblies and how they kill neurons has not yet been ach
Externí odkaz:
https://doaj.org/article/dcd1163f62ff4d7e8a317831ac0dfb7d
Autor:
Jeffrey L. Schloßhauer, Lena Tholen, Alexander Körner, Stefan Kubick, Sofia Chatzopoulou, Anja Hönow, Anne Zemella
Publikováno v:
Synthetic and Systems Biotechnology, Vol 9, Iss 3, Pp 416-424 (2024)
Chinese hamster ovary (CHO) cells are crucial in biopharmaceutical production due to their scalability and capacity for human-like post-translational modifications. However, toxic proteins and membrane proteins are often difficult-to-express in livin
Externí odkaz:
https://doaj.org/article/135f28cf17b64878a5997cacbe96703b
Publikováno v:
The Journal of Physical Chemistry B. 125:12426-12435
Transient oligomeric intermediates in the peptide or protein aggregation pathway are suspected to be the key toxic species in many amyloid diseases, but deciphering their molecular nature has remained a challenge. Here we show that the strategy of "d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::279fce16da5d67a7cca67c8fcfe3c344
https://doi.org/10.1021/acs.jpcb.1c05829
https://doi.org/10.1021/acs.jpcb.1c05829
Autor:
Aude Ingels, Robert Scott, Annie R. Hooper, Aletta E. van der Westhuyzen, Sachin B. Wagh, Joséphine de Meester, Lucia Maddau, Doris Marko, Georg Aichinger, Walter Berger, Marjorie Vermeersch, David Pérez-Morga, Vladimir A. Maslivetc, Antonio Evidente, Willem A. L. van Otterlo, Alexander Kornienko, Véronique Mathieu
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Sphaeropsidins are iso-pimarane diterpenes produced by phytopathogenic fungi that display promising anticancer activities. Sphaeropsidin A, in particular, has been shown to counteract regulatory volume increase, a process used by cancer cell
Externí odkaz:
https://doaj.org/article/6c21a3354a474dd69508d75741c9d1ba
Autor:
Daniel Huster, Corinna Höfling, Steffen Roßner, Alexander Korn, Martin Krueger, Ulrike Zeitschel
Publikováno v:
ACS Chemical Neuroscience. 11:1038-1047
The nonproteinogenic amino acid β-methylamino alarelevant example for environmental hazards are nonnine (BMAA) is a neurotoxin and represents a potential risk factor for neurodegenerative diseases. Despite intense research over the last years, the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94d9f435786c8174c0bf25c0e78d55e4
https://doi.org/10.1021/acschemneuro.9b00660
https://doi.org/10.1021/acschemneuro.9b00660
Publikováno v:
ECS Transactions. 96:191-201
Highly efficient cathode air filters are required to enable the required fuel cell system´s lifetime, especially under severe operating conditions. In addition, components like water separators, compressors, air ducts, coolers, humidifiers, sensors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc3cee8cb13615ff0aea40187f424d27
https://doi.org/10.1149/09601.0191ecst
https://doi.org/10.1149/09601.0191ecst
Publikováno v:
Physical Chemistry Chemical Physics. 22:16887-16895
Neuronal plaques of amyloid β (Aβ) peptides of varying length carrying different posttranslational modifications represent a molecular hallmark of Alzheimer's disease. It is believed that transient oligomeric Aβ assemblies associating in early fib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50454de56afbb237cd4d5065f5a7f11a
https://doi.org/10.1039/d0cp02307h
https://doi.org/10.1039/d0cp02307h
Autor:
Huster, Jacob Fritzsch, Alexander Korn, Dayana Surendran, Martin Krueger, Holger A. Scheidt, Kaustubh R. Mote, Perunthiruthy K. Madhu, Sudipta Maiti, Daniel
Publikováno v:
Biomolecules; Volume 11; Issue 12; Pages: 1848
Amyloid β (Aβ) is a peptide known to form amyloid fibrils in the brain of patients suffering from Alzheimer’s disease. A complete mechanistic understanding how Aβ peptides form neurotoxic assemblies and how they kill neurons has not yet been ach
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::94950c197bce1deef617f6218d437005
Publikováno v:
SAE Technical Paper Series.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf9a5ef4dd3cdc89f54554a01963eb09
https://doi.org/10.4271/2020-01-1176
https://doi.org/10.4271/2020-01-1176