Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Alexander Kloss"'
Autor:
Ricardo Camargo, Liliam O Faria, Alexander Kloss, Cecília B F Favali, Ulrike Kuckelkorn, Peter-Michael Kloetzel, Cezar Martins de Sá, Beatriz D Lima
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e95977 (2014)
Generally, Trypanosoma cruzi infection in human is persistent and tends to chronicity, suggesting that the parasite evade the immune surveillance by down regulating the intracellular antigen processing routes. Within the MHC class I pathway, the majo
Externí odkaz:
https://doaj.org/article/501a6b8aba65450ea39d9a454900fdd9
Autor:
Carolin Giannini, Alexander Kloß, Sabrina Gohlke, Michele Mishto, Thomas P Nicholson, Paul W Sheppard, Peter-Michael Kloetzel, Burkhardt Dahlmann
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64042 (2013)
Proteostasis is critical for the maintenance of life. In neuronal cells an imbalance between protein synthesis and degradation is thought to be involved in the pathogenesis of neurodegenerative diseases during aging. Partly, this seems to be due to a
Externí odkaz:
https://doaj.org/article/a35a41333648407d91fdc5a9b6e666b6
Autor:
Peter-Michael Kloetzel, Alexander Kloss, Kathrin Textoris-Taube, Sabrina Gohlke, Christin Keller, Burkhardt Dahlmann, Michael Tsokos
Publikováno v:
Annals of Hepatology, Vol 13, Iss 4, Pp 429-438 (2014)
Background. The 20S proteasome is the proteolytic core of the major intracellular protein degradative system, the ubiquitin-proteasome system. Since little is known about proteasomes of human liver, we have investigated the proteasome spectrum in adu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79738652ee908b9a5c89583fd76944e6
http://www.sciencedirect.com/science/article/pii/S1665268119308506
http://www.sciencedirect.com/science/article/pii/S1665268119308506
Autor:
Anne Wiemhoefer, Alicia Sanz Sanz, Eric Reits, Alexander Kloss, Sabine Schipper-Krom, Katrin Juenemann
Publikováno v:
Journal of biological chemistry, 288(38), 27068-27084. American Society for Biochemistry and Molecular Biology Inc.
Huntington disease is a neurodegenerative disorder caused by an expanded polyglutamine (polyQ) repeat within the protein huntingtin (Htt). N-terminal fragments of the mutant Htt (mHtt) proteins containing the polyQ repeat are aggregation-prone and fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::532840a25937a649ad331030e3a2024e
https://doi.org/10.1074/jbc.m113.486076
https://doi.org/10.1074/jbc.m113.486076
Autor:
Alexander Kloss, Burkhardt Dahlmann, Petra Henklein, Katharina Janek, Andrean Goede, Christin Keller, Michele Mishto, Agathe Niewienda, Sabrina Gohlke, Kathrin Textoris Taube, Cordula Enenkel, Peter M. Kloetzel
Publikováno v:
Molecular & Cellular Proteomics. 11:1008-1023
Proteasome-catalyzed peptide splicing (PCPS) represents an additional activity of mammalian 20S proteasomes recently identified in connection with antigen presentation. We show here that PCPS is not restricted to mammalians but that it is also a feat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77994c5d9c2bf055dc0de26972fa4441
https://doi.org/10.1074/mcp.m112.020164
https://doi.org/10.1074/mcp.m112.020164
Autor:
Jan Giesebrecht, Alexander Kloss, Michael Adamzik, Jeremias Wohlschlaeger, Boris Saul, Stephan Urs Sixt, Jürgen Peters, Jan Hakenbeck, Daniel Spyrka, Burkhardt Dahlmann, Ulrich Costabel
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 179:1098-1106
Repair mechanisms resulting in alveolar protein degradation in acute respiratory distress syndrome (ARDS) are largely unknown.To test whether the 20S proteasome is present and functional in the alveolar space in patients with ARDS.Proteasome antigeni
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2668091f9e6027bb33d33a6387f81163
https://doi.org/10.1164/rccm.200802-199oc
https://doi.org/10.1164/rccm.200802-199oc
Autor:
Paul W. Sheppard, Marion Schmolke, Alexander Kloss, Dagmar Siele, Peter Henklein, Burkhardt Dahlmann, Sébastien Apcher, Lothar Kuehn
Publikováno v:
European Journal of Pharmaceutics and Biopharmaceutics. 72:219-225
Oligo-arginines are cell-penetrating peptides and find use as carriers for transportation of various membrane-impermeable biopharmaceuticals into target cells. We have found that oligo-arginines of a length of 4-10 amino acids, but especially (Arg)(8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faea7206f4ac9b6b2f3cc04be1b65402
https://doi.org/10.1016/j.ejpb.2008.10.016
https://doi.org/10.1016/j.ejpb.2008.10.016
Autor:
Martijn Verdoes, Hermen S. Overkleeft, Clemens Ruppert, Serge Adnot, Elisabeth Marcos, Andreas Günther, Susanne Herold, Oliver Vosyka, Burkhardt Dahlmann, Stefanie M. Hauck, Lianne I. Willems, Ilona Keller, Shinji Takenaka, Heiko Adler, Shinji Ohno, Silke Meiners, Alexander Kloß, Oliver Eickelberg
Publikováno v:
Scientific Reports, 5, 10230
Sci. Rep. 5:10230 (2015)
Scientific Reports
Scientific Reports, 5
Sci. Rep. 5:10230 (2015)
Scientific Reports
Scientific Reports, 5
Contains fulltext : 152662.pdf (Publisher’s version ) (Open Access) Impaired immune function contributes to the development of chronic obstructive pulmonary disease (COPD). Disease progression is further exacerbated by pathogen infections due to im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98620dd830e949c1eb56e4df59ff4ad8
http://hdl.handle.net/1887/49468
http://hdl.handle.net/1887/49468
Autor:
Francesco Vasuri, Alessio Degiovanni, Alexander Kloss, Daniel Remondini, Stefano Salvioli, Morena Martucci, Elisa Capizzi, Alessandro Dazzi, Michele Mishto, Gian Luca Grazi, Matteo Cescon, Antonia D’Errico-Grigioni, Claudio Franceschi, Burkhardt Dahlmann, S. Pellegrini, Catia Lanzarini, Elena Bellavista, Miriam Capri, Aurelia Santoro
Publikováno v:
Mechanisms of ageing and development.
Owing to organ shortage, livers from old donors are increasingly used for transplantation. The function and duration of such transplanted livers are apparently comparable to those from young donors, suggesting that, despite some morphological and str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14c021c844ddd7e0592a0a68d088f144
https://pubmed.ncbi.nlm.nih.gov/25265087
https://pubmed.ncbi.nlm.nih.gov/25265087
Autor:
Johannes Felsenberg, Peter-Michael Kloetzel, Dorothea Eisenhardt, Alexander Kloß, Yan Dyck, Burkhardt Dahlmann
Publikováno v:
Journal of Experimental Biology.
In honeybees (Apis mellifera) the proteasome inhibitor Z-Leu-Leu-Leu-CHO (MG132) enhances long-term memory (LTM) formation. Studies in vertebrates using different inhibitors of the proteasome demonstrate the opposite, namely an inhibition of memory f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3de855f5fb6fe449c150b03ecb1990d
https://doi.org/10.1242/jeb.108142
https://doi.org/10.1242/jeb.108142