Time trends in prevalence of p16 positivity and combined HPV/p16 positivity in a large cohort of Danish vulvar cancer patients

Autor: Christina Louise Rasmussen, Louise T. Thomsen, Louise Baandrup, Maria Benedicte Franzmann, Alexander K. Kjær, Lise Grupe Larsen, Else Mejlgaard Madsen, Nadia Margeth Villena Salinas, Doris Schledermann, Birgitte Hjelm Winberg, Dorthe Ørnskov, Marianne Waldstrøm, Susanne K. Kjær

Publikováno v: Rasmussen, C L, Thomsen, L T, Baandrup, L, Franzmann, M B, Kjær, A K, Larsen, L G, Madsen, E M, Salinas, N M V, Schledermann, D, Winberg, B H, Ørnskov, D, Waldstrøm, M & Kjær, S K 2023, ' Time trends in prevalence of p16 positivity and combined HPV/p16 positivity in a large cohort of Danish vulvar cancer patients ', International Journal of Cancer, vol. 152, no. 11, pp. 2424-2432 . https://doi.org/10.1002/ijc.34446

Vulvar cancer is rare, but causes substantial morbidity in affected patients. A subset of vulvar cancers is caused by high-risk human papillomavirus (hrHPV), which primarily exerts its oncogenic effect through upregulation of tumor suppressor protein

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::546f573a428927b106e5edacd4432790
https://vbn.aau.dk/da/publications/ed0f47c3-37aa-4618-b392-87ac673ef04b

The prognostic significance of HPV, p16, and p53 protein expression in vaginal cancer: A systematic review

Autor: Christina Louise Rasmussen, Hanna Kristina Bertoli, Alexander K. Kjaer, Susanne K. Kjaer, Louise T. Thomsen, Freja Lærke Sand

Publikováno v: Rasmussen, C L, Bertoli, H K, Sand, F L, Kjær, A K, Thomsen, L T & Kjær, S K 2021, ' The prognostic significance of HPV, p16, and p53 protein expression in vaginal cancer : A systematic review ', Acta Obstetricia et Gynecologica Scandinavica, vol. 100, no. 12, pp. 2144-2156 . https://doi.org/10.1111/aogs.14260

Introduction: Human papillomavirus (HPV), p16, and p53 have been investigated as prognostic markers in various HPV-related cancers. Within the field of vaginal cancer, however, the evidence remains sparse. In this systematic review, we have compiled

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ff2ace0b1ee62b8915f811ce0791e98
https://doi.org/10.1111/aogs.14260

Time trends in the incidence and survival of vaginal squamous cell carcinoma and high-grade vaginal intraepithelial neoplasia in Denmark - A nationwide population-based study

Autor: Louise Baandrup, Susanne K. Kjaer, Louise T. Thomsen, Gitte Lerche Aalborg, Alexander K. Kjaer, Hanna Kristina Bertoli

Publikováno v: Gynecologic oncology. 158(3)

To describe trends in incidence of high-grade vaginal intraepithelial neoplasia (VaIN) and vaginal squamous cell carcinoma (SCC) in Denmark. For vaginal SCC, we also examine 5-year relative survival and mortality.All high-grade VaIN cases diagnosed 1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dbb724dd8322efe6ae37947f051bf66
https://pubmed.ncbi.nlm.nih.gov/32571683