Zobrazeno 1 - 10
of 235
pro vyhledávání: '"Alexander KÖNIG"'
Autor:
Fabian Weiss, Till Kaltofen, Veronika Kanitz, Lennard Schröder, Bernd Kost, Alexander König, Maria Delius, Sven Mahner, Irene Alba Alejandre
Publikováno v:
Journal of Medical Case Reports, Vol 17, Iss 1, Pp 1-6 (2023)
Abstract Background Endometrial carcinomas are the most common female genital malignancies. They are very rare in pregnancy and worldwide less than 60 cases associated with pregnancy are published. No clear cell carcinoma has been described in a preg
Externí odkaz:
https://doaj.org/article/023dfae12dc940cd8bfc878cb09e376e
Autor:
Thomas Seufferlein, Ludwig Lausser, Alexander Stein, Dirk Arnold, Gerald Prager, Stefan Kasper-Virchow, Michael Niedermeier, Lothar Müller, Stefan Kubicka, Alexander König, Petra Büchner-Steudel, Kai Wille, Andreas W Berger, Angelika M R Kestler, Johann M Kraus, Silke D Werle, Lukas Perkhofer, Thomas J Ettrich, Hans A Kestler
Publikováno v:
PLoS ONE, Vol 19, Iss 6, p e0304324 (2024)
BackgroundAnti-vascular endothelial growth factor (VEGF) monoclonal antibodies (mAbs) are widely used for tumor treatment, including metastatic colorectal cancer (mCRC). So far, there are no biomarkers that reliably predict resistance to anti-VEGF mA
Externí odkaz:
https://doaj.org/article/70304decadfc447c8eecb19ea70285b5
Autor:
Friederike Braulke, Kathrin Kober, Andreas Arndt, Maximilian Papendick, Arne Strauss, Christof Maria Kramm, Kai-Martin Thoms, Alexander König, Jochen Gaedcke, Julia Gallwas, Svenja Wulf, Christoph Szuszies, Gerald Wulf, Ralph Rödel, Susanne Wolfer, Vesna Malinova, Tobias R. Overbeck, Marc Hinterthaner, Joachim Lotz, Friedemann Nauck, Marielle Ernst, Christine Stadelmann, Philipp Ströbel, Volker Ellenrieder, Thomas Asendorf, Stefan Rieken
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
IntroductionMulti-professional interdisciplinary tumor boards (ITB) are essential institutions to discuss all newly diagnosed, relapsed or complex cancer patients in a team of specialists to find an optimal cancer care plan for each individual patien
Externí odkaz:
https://doaj.org/article/d89f4a014aa445bd8cdf487b1b57a9f6
Autor:
Alexandra Stefan, Marija Petkovic, Alexander König, Julian Koch, Friederike Hagemann, Rachel Wuerstlein, Nadia Harbeck, Sven Mahner, Till Kaltofen
Publikováno v:
Journal of Medical Case Reports, Vol 16, Iss 1, Pp 1-7 (2022)
Abstract Purpose During the severe acute respiratory syndrome coronavirus 2 pandemic, several patient groups are at particular risk. Mortality is higher among cancer patients and may be increased further by thromboembolic events, which are more commo
Externí odkaz:
https://doaj.org/article/0919b51fbea145378a6e1ef8df480f75
Autor:
Sebastian Krug, Thomas Kegel, Thomas M. Gress, Anja Rinke, Leonidas Apostolidis, Henning Jann, Alexander König, Dieter Hörsch, Jörg Schrader, Thomas J. Ettrich, Michael Richter, Jörg Steighardt, Patrick Michl
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-9 (2021)
Abstract Background Cytotoxic chemotherapy combinations and targeted agents represent established treatment concepts in advanced pancreatic neuroendocrine tumors (PNETs). However, response rates, side effects and outcome data strongly vary among thes
Externí odkaz:
https://doaj.org/article/19ea4eac44d448f1a68eca27024409f7
Autor:
Mariano Genera, Barbara Quioc-Salomon, Antonin Nourisson, Baptiste Colcombet-Cazenave, Ahmed Haouz, Ariel Mechaly, Mariette Matondo, Magalie Duchateau, Alexander König, Marc P. Windisch, Christine Neuveut, Nicolas Wolff, Célia Caillet-Saguy
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract Interactions between the hepatitis B virus core protein (HBc) and host cell proteins are poorly understood, although they may be essential for the propagation of the virus and its pathogenicity. HBc has a C-terminal PDZ (PSD-95, Dlg1, ZO-1)-
Externí odkaz:
https://doaj.org/article/1aa13d44608f4a1a8117b0820723178a
Autor:
Azadeh Azizian, Alexander König, Amelie Hartmann, Frank Schuppert, Ali Seif Amir Hosseini, Julia Kitz, Michael Ghadimi
Publikováno v:
Therapeutic Advances in Gastroenterology, Vol 14 (2021)
VIPoma, a neuroendocrine tumour mostly occurring in the human pancreas and producing high levels of vasoactive intestinal peptide, is a rare disease that presents with a wide spectrum of symptoms, including intense diarrhoea, hypokalaemia, and cardia
Externí odkaz:
https://doaj.org/article/60b2f692bba54112a405d42bac55dd4a
Autor:
Jaewon Yang, Alexander König, Soonju Park, Eunji Jo, Pil Soo Sung, Seung Kew Yoon, Eva Zusinaite, Denis Kainov, David Shum, Marc Peter Windisch
Publikováno v:
JHEP Reports, Vol 3, Iss 4, Pp 100296- (2021)
Background & Aims: Chronic hepatitis B is an incurable disease. Addressing the unmet medical need for therapies has been hampered by a lack of suitable cell culture models to investigate the HBV life cycle in a single experimental setup. We sought to
Externí odkaz:
https://doaj.org/article/1e0390c1447c43c2833a8a97f1de481f
Autor:
Lena-Christin Conradi, Melanie Spitzner, Anna-Lena Metzger, Merle Kisly, Peter Middel, Hanibal Bohnenberger, Jochen Gaedcke, Michael B. Ghadimi, Torsten Liersch, Joseph Rüschoff, Tim Beißbarth, Alexander König, Marian Grade
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-12 (2019)
Abstract Background Abrogation of growth factor-dependent signaling represents an effective therapeutic strategy for patients with colorectal cancer (CRC). Here we evaluated the effectiveness of targeting the epidermal growth factor (EGF) receptors H
Externí odkaz:
https://doaj.org/article/6b00a26effe1468b968df1dc6e299f26
Autor:
Thomas J. Ettrich, Andreas W. Berger, Lukas Perkhofer, Severin Daum, Alexander König, Andreas Dickhut, Uwe Wittel, Kai Wille, Michael Geissler, Hana Algül, Eike Gallmeier, Jens Atzpodien, Marko Kornmann, Rainer Muche, Nicole Prasnikar, Andrea Tannapfel, Anke Reinacher-Schick, Waldemar Uhl, Thomas Seufferlein
Publikováno v:
BMC Cancer, Vol 18, Iss 1, Pp 1-10 (2018)
Abstract Background Even clearly resectable pancreatic cancer still has an unfavorable prognosis. Neoadjuvant or perioperative therapies might improve the prognosis of these patients. Thus, evaluation of perioperative chemotherapy in resectable pancr
Externí odkaz:
https://doaj.org/article/4b8d6fac7cb54c6aaa9dcd06f710f790