Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Alexander K, Tsai"'
Autor:
Eduardo Davila, Yuanyuan Liang, Lucy L. Wang, Christina E. Worgo, Asra Y. Khan, Alexander K. Tsai
Fig. S1: SC200 library HTS candidate drugs. Fig. S2: Effects of EGFR, VEGFR, MEK, and p38 candidate inhibitors on PD-L1 and HLA-I in a melanoma panel and on T-cell proliferation. Fig. S3: Effects of BRAF, PI3K, mTOR, and Src candidate inhibitors on P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6d3932624f93f507e8fcd5d6991ab0a
https://doi.org/10.1158/2326-6066.22540096
https://doi.org/10.1158/2326-6066.22540096
Autor:
Eduardo Davila, Yuanyuan Liang, Lucy L. Wang, Christina E. Worgo, Asra Y. Khan, Alexander K. Tsai
Supplementary Data Description
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55ef1827dad8d771e55493e0fe046293
https://doi.org/10.1158/2326-6066.22540102.v1
https://doi.org/10.1158/2326-6066.22540102.v1
Autor:
Eduardo Davila, Yuanyuan Liang, Lucy L. Wang, Christina E. Worgo, Asra Y. Khan, Alexander K. Tsai
Combination therapies have the potential to improve outcomes in melanoma patients but have not yet been clinically efficacious. Here, we used high-throughput flow cytometry-based screening to identify and characterize candidate therapies that might s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f643daaf810eaac3dff5e702dc4e071
https://doi.org/10.1158/2326-6066.c.6549280.v1
https://doi.org/10.1158/2326-6066.c.6549280.v1
Autor:
Eduardo Davila, Cruz Velasco Gonzales, Yuji Zhang, Kenisha Younger, Jackline Joy Lasola, Alexander K Tsai, Jitao Guo, Ann Mary Joseph, Sabina Kaczanowska
These data demonstrate that a single injection of CD8a:MyD88 T cells delay tumor progression and can prolong mouse survival.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a75093e83d898cc1771da86b98efa002
https://doi.org/10.1158/0008-5472.22416275.v1
https://doi.org/10.1158/0008-5472.22416275.v1
Autor:
Eduardo Davila, Cruz Velasco Gonzales, Yuji Zhang, Kenisha Younger, Jackline Joy Lasola, Alexander K Tsai, Jitao Guo, Ann Mary Joseph, Sabina Kaczanowska
These data demonstrate that CD8a:MyD88 expression increases IFN gamma production and induces the expression of various co-stimulatory and co-inhibitory molecules on T cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f48392cc74f04c1d172ebccd4e65b5d
https://doi.org/10.1158/0008-5472.22416284
https://doi.org/10.1158/0008-5472.22416284
Autor:
Eduardo Davila, Cruz Velasco Gonzales, Yuji Zhang, Kenisha Younger, Jackline Joy Lasola, Alexander K Tsai, Jitao Guo, Ann Mary Joseph, Sabina Kaczanowska
These data show the vector constructs verify expression of the intended protein.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a944cab9143d8152eae733d773b0682
https://doi.org/10.1158/0008-5472.22416287
https://doi.org/10.1158/0008-5472.22416287
Autor:
Eduardo Davila, Cruz Velasco Gonzales, Yuji Zhang, Kenisha Younger, Jackline Joy Lasola, Alexander K Tsai, Jitao Guo, Ann Mary Joseph, Sabina Kaczanowska
These data demonstrate that neither checkpoint blockade using anti-PD-L1 or costimulation using anti-4-1BB antibodies enhance pmel CD8a:MyD88 T cells antitumor activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cba1f56b225ad1a3c248feae97e7675
https://doi.org/10.1158/0008-5472.22416272.v1
https://doi.org/10.1158/0008-5472.22416272.v1
Autor:
Eduardo Davila, Cruz Velasco Gonzales, Yuji Zhang, Kenisha Younger, Jackline Joy Lasola, Alexander K Tsai, Jitao Guo, Ann Mary Joseph, Sabina Kaczanowska
These data show changes in the levels of cytokines and chemokines induced by CD8a:MyD88 expression in T cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab1a07a63bc5269f83161927f805da30
https://doi.org/10.1158/0008-5472.22416281.v1
https://doi.org/10.1158/0008-5472.22416281.v1
Autor:
Eduardo Davila, Cruz Velasco Gonzales, Yuji Zhang, Kenisha Younger, Jackline Joy Lasola, Alexander K Tsai, Jitao Guo, Ann Mary Joseph, Sabina Kaczanowska
T cell–based immunotherapies are a promising approach for patients with advanced cancers. However, various obstacles limit T-cell efficacy, including suboptimal T-cell receptor (TCR) activation and an immunosuppressive tumor environment. Here, we d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::193ea8dedfc00e4647b1dd8edb28aebc
https://doi.org/10.1158/0008-5472.c.6509513
https://doi.org/10.1158/0008-5472.c.6509513
Autor:
Eduardo Davila, Cruz Velasco Gonzales, Yuji Zhang, Kenisha Younger, Jackline Joy Lasola, Alexander K Tsai, Jitao Guo, Ann Mary Joseph, Sabina Kaczanowska
These data show changes in the levels of cytokines and chemokines in tumors induced by CD8a:MyD88-expressing T cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b86c21753bc8dee94fe946f734b6f7a
https://doi.org/10.1158/0008-5472.22416278
https://doi.org/10.1158/0008-5472.22416278