Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Alexander Johnson-Buck"'
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Traces from single-molecule fluorescence microscopy (SMFM) experiments exhibit photophysical artifacts that typically make analysis time-consuming. Here, the authors have developed an easily accessible software, AutoSiM, for two distinct applications
Externí odkaz:
https://doaj.org/article/e41c9c9671084acbbaf16ef58f178d60
Autor:
Zhao Zhao, Jinglin Fu, Soma Dhakal, Alexander Johnson-Buck, Minghui Liu, Ting Zhang, Neal W. Woodbury, Yan Liu, Nils G. Walter, Hao Yan
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
Cells compartmentalize enzymes for enhanced efficiency of their metabolic pathways. Here, the authors describe a self-assembly approach to construct DNA nanocaged enzymes for enhancing catalytic activity and stability, and observe an inversed correla
Externí odkaz:
https://doaj.org/article/0c8994d2379840b6bc7c9a797d47c2d7
Publikováno v:
ACS Sensors. 7:1419-1430
From longstanding techniques like enzyme-linked immunosorbent assay (ELISA) to modern next-generation sequencing, many of the most sensitive and specific biomarker detection assays require capture of the analyte at a surface. While surface-based assa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d52b024b649f8991d68f6ab0438807f
https://doi.org/10.1021/acssensors.2c00135
https://doi.org/10.1021/acssensors.2c00135
Publikováno v:
Methods
Cell-free nucleic acids (cfNAs) such as short non-coding microRNA (miRNA) and circulating tumor DNA (ctDNA) that reside in bodily fluids have emerged as potential cancer biomarkers. Methods for the rapid, highly specific, and sensitive monitoring of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b204df6f5f144f19a66a5bf3ad3e08e0
https://doi.org/10.1016/j.ymeth.2021.06.014
https://doi.org/10.1016/j.ymeth.2021.06.014
Autor:
Andrew Ward, Darren Yang, Wesley P. Wong, Serkan Cabi, Elisha Krieg, Bhavik Nathwani, Prakash Shrestha, Yi Luo, Toma E. Tomov, William M. Shih, James I. MacDonald, Hans T. Bergal, Alexander Johnson-Buck
Publikováno v:
Nature Nanotechnology. 16:1362-1370
Decoding the identity of biomolecules from trace samples is a longstanding goal in the field of biotechnology. Advances in DNA analysis have substantially affected clinical practice and basic research, but corresponding developments for proteins face
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::726d7e5e758032a33e31cc8662ea38e0
https://doi.org/10.1038/s41565-021-00979-0
https://doi.org/10.1038/s41565-021-00979-0
Autor:
Tanmay Chatterjee, Ning Liu, Achim Knappik, Sung Won Choi, Evan Thrush, Kenneth J. Oh, Erin Sandford, Muneesh Tewari, Alexander Johnson-Buck, Nils G. Walter, William Strong
Publikováno v:
Proc Natl Acad Sci U S A
The sensitive and accurate quantification of protein biomarkers plays important roles in clinical diagnostics and biomedical research. Sandwich ELISA and its variants accomplish the capture and detection of a target protein via two antibodies that ti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec03af7f49c62b4ba099b0663d87e863
https://doi.org/10.1073/pnas.2008312117
https://doi.org/10.1073/pnas.2008312117
Publikováno v:
Nano Letters. 20:2688-2694
Simultaneous analysis based on encoded fluorophores suffers from potential crosstalk between fluorophores and the limited number of colors that can be practically resolved. Inspired by nontrivial temporal patterns in living organisms, we developed a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2894a30fc1de636763781a8cba78cda0
https://doi.org/10.1021/acs.nanolett.0c00313
https://doi.org/10.1021/acs.nanolett.0c00313
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c44eb499d654a3348088110e3f0098e4
https://doi.org/10.2139/ssrn.4109678
https://doi.org/10.2139/ssrn.4109678
Publikováno v:
Biosensors and Bioelectronics. 216:114639
Sensitive assays of protein biomarkers play critical roles in clinical diagnostics and biomedical research. Such assays typically employ immunoreagents such as monoclonal antibodies that suffer from several drawbacks, including relatively tedious pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c681d02a6cdf682e73c0309f4d29d29
https://doi.org/10.1016/j.bios.2022.114639
https://doi.org/10.1016/j.bios.2022.114639
Autor:
Prakash, Shrestha, Darren, Yang, Toma E, Tomov, James I, MacDonald, Andrew, Ward, Hans T, Bergal, Elisha, Krieg, Serkan, Cabi, Yi, Luo, Bhavik, Nathwani, Alexander, Johnson-Buck, William M, Shih, Wesley P, Wong
Publikováno v:
Nature nanotechnology. 16(12)
Decoding the identity of biomolecules from trace samples is a longstanding goal in the field of biotechnology. Advances in DNA analysis have substantially affected clinical practice and basic research, but corresponding developments for proteins face
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9cced109efbc98b7858e4295730d4e1d
https://pubmed.ncbi.nlm.nih.gov/34675411
https://pubmed.ncbi.nlm.nih.gov/34675411