Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Alexander Janssen"'
Autor:
Alexander Janssen, Mark Hoogendoorn, Marjon H. Cnossen, Ron A. A. Mathôt, the OPTI‐CLOT Study Group and SYMPHONY Consortium
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 11, Iss 8, Pp 1100-1110 (2022)
Abstract In population pharmacokinetic (PK) models, interindividual variability is explained by implementation of covariates in the model. The widely used forward stepwise selection method is sensitive to bias, which may lead to an incorrect inclusio
Externí odkaz:
https://doaj.org/article/0ab8e6d545d7478e9376b677b1290db2
Autor:
Alexander Janssen, Frank W. G. Leebeek, Marjon H. Cnossen, Ron A. A. Mathôt, the OPTI‐CLOT study group and SYMPHONY consortium
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 11, Iss 7, Pp 934-945 (2022)
Abstract Nonlinear mixed effect (NLME) models are the gold standard for the analysis of patient response following drug exposure. However, these types of models are complex and time‐consuming to develop. There is great interest in the adoption of m
Externí odkaz:
https://doaj.org/article/9c0772ba25f9456fb3e8391b85d47457
Publikováno v:
Pharmaceutics, Vol 14, Iss 9, p 1814 (2022)
Pharmacometrics is a multidisciplinary field utilizing mathematical models of physiology, pharmacology, and disease to describe and quantify the interactions between medication and patient. As these models become more and more advanced, the need for
Externí odkaz:
https://doaj.org/article/f200a32e4c3e4962b06dd1fb9a7fb7f8
Autor:
Nina Graupner, Karl-Heinz Lehmann, David E. Weber, Hans-Willi Hilgers, Erik G. Bell, Isabel Walenta, Luisa Berger, Torsten Brückner, Kay Kölzig, Herbert Randerath, Albert Bruns, Bernd Frank, Maik Wonneberger, Marc Joulian, Lisa Bruns, Friedrich von Dungern, Alexander Janßen, Thomas Gries, Stefan Kunst, Jörg Müssig
Publikováno v:
Materials, Vol 14, Iss 1, p 105 (2020)
The use of natural fibres for components subjected to higher mechanical requirements tends to be limited by the high price of high-quality semi-finished products. Therefore, the present study deals with the development of more cost-effective staple f
Externí odkaz:
https://doaj.org/article/2ddd3f63ad0a4642bad58e834ee690c1
Autor:
Alexander Janßen, André Wizemann, André Klicpera, Dewi Y. Satari, Hildegard Westphal, Thomas Mann
Publikováno v:
Frontiers in Marine Science, Vol 4 (2017)
Sedimentological and geomorphological characteristics of coral reef islands are strongly related to past and recent boundary conditions such as the hydrodynamic regime, wind directions, sea-level fluctuations, and the ecological footprint of the surr
Externí odkaz:
https://doaj.org/article/24a81a8824484ea0bfff65ca943e3750
The potential of using chatGPT in pharmacometrics was explored in this study, with a focus on developing a pharmacokinetic (PK) model for standard half-life factor VIII. Our results demonstrated that chatGPT can be utilized to accurately obtain typic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84b8c4b92ff07a9fd7153f74970792b6
https://doi.org/10.22541/au.168235933.39569649/v1
https://doi.org/10.22541/au.168235933.39569649/v1
Publikováno v:
Janssen, A, de Waele, J J & Elbers, P W G 2023, ' Towards adequate and automated antibiotic dosing ', Intensive Care Medicine, vol. 49, no. 7, pp. 853-856 . https://doi.org/10.1007/s00134-023-07047-2
Intensive care medicine. Springer Verlag
Intensive Care Medicine. Springer Verlag
Intensive care medicine. Springer Verlag
Intensive Care Medicine. Springer Verlag
Autor:
Carel F.E. Hoffmann, Maria Fiorella Contarino, Femke M.P. Zitman, Alexander Janssen, Rodi Zutt, Niels A van der Gaag
Publikováno v:
Parkinsonism & Related Disorders, 93, 58-61. ELSEVIER SCI LTD
Introduction: Directional deep brain stimulation (DBS) and pulse with
Perioperative pharmacokinetic-guided factor VIII concentrate dosing in haemophilia (OPTI-CLOT trial)
Autor:
Iris van Moort, Tim Preijers, Laura H Bukkems, Hendrika C A M Hazendonk, Johanna G van der Bom, Britta A P Laros-van Gorkom, Erik A M Beckers, Laurens Nieuwenhuizen, Felix J M van der Meer, Paula Ypma, Michiel Coppens, Karin Fijnvandraat, Roger E G Schutgens, Karina Meijer, Frank W G Leebeek, Ron A A Mathôt, Marjon H Cnossen, Marjon H. Cnossen, Frank W.G. Leebeek, Ron A.A. Mathôt, Marieke J.H.A. Kruip, Suzanne Polinder, Janske Lock, Hendrika C.A.M. Hazendonk, Iris Van Moort, Jessica M. Heijdra, Marie C.H.J. Goedhart, Wala Al Arashi, Nico C.B. De Jager, Laura H. Bukkems, Michael E. Cloesmeijer, Alexander Janssen, Rienk Y.J. Tamminga, Paul Brons, Saskia E.M. Schols, Jeroen C.J. Eikenboom, Felix J.M. Van der Meer, Roger E.G. Schutgens, Kathelijne Fischer, Karin P.M. Van Galen, Erik E.A.M. Beckers, Floor C.J.I. Heubel-Moenen, Mariëtte H.E. Driessens, Ineke Van Vliet, Peter W. Collins, Ri Liesner, Pratima Chowdary, Carolyn M. Millar, Dan Hart, David Keeling
Publikováno v:
The Lancet Haematology, 8(7), e492-e502. Lancet Publishing Group
Lancet. Haematology, 8(7), e492-e502. Lancet Publishing Group
Lancet Haematology, 8, e492-e502
Lancet Haematology, 8(7), E492-E502. ELSEVIER SCI LTD
The Lancet Haematology, 8(7), E492-E502. ELSEVIER SCI LTD
Lancet Haematology, 8, 7, pp. e492-e502
Lancet. Haematology, 8(7), e492-e502. Lancet Publishing Group
Lancet Haematology, 8, e492-e502
Lancet Haematology, 8(7), E492-E502. ELSEVIER SCI LTD
The Lancet Haematology, 8(7), E492-E502. ELSEVIER SCI LTD
Lancet Haematology, 8, 7, pp. e492-e502
Contains fulltext : 237493.pdf (Publisher’s version ) (Closed access) BACKGROUND: Dosing of replacement therapy with factor VIII concentrate in patients with haemophilia A in the perioperative setting is challenging. Underdosing and overdosing of f
Autor:
Marjon H. Cnossen, Iris van Moort, Simone H. Reitsma, Moniek P.M. de Maat, Roger E.G. Schutgens, Rolf T. Urbanus, Hester F. Lingsma, Ron A.A. Mathot, Samantha C. Gouw, Karina Meijer, Annelien L. Bredenoord, Rieke van der Graaf, Karin Fijnvandraat, Alexander B. Meijer, Emile van den Akker, Ruben Bierings, Jeroen C.J. Eikenboom, Maartje van den Biggelaar, Masja de Haas, Jan Voorberg, Frank W.G. Leebeek, Ryanne A. Arisz, Minka Zivkovic, E. Shannon van Hoorn, Laura H. Bukkems, Tine M.C.H.J. Goedhart, Lorenzo G.R. Romano, Wala Al Arashi, Michael E. Cloesmeijer, Alexander Janssen, Martijn R. Brands, Lieke Baas, Jessica del Castillo Alferez, Huan Zhang, Sebastiaan N.J. Laan, Johan Boender, Johanna G. van der Bom, Mettine H.A. Bos, Lex Burdorf, Michiel Coppens, Mariette Driessens, Kathelijne F. Fischer, Lotte Haverman, Jan A. Hazelzet, Elise J. Huisman, Natalie Jansen, Sean de Jong, Marieke Kruip, Nikki van Leeuwen, Felix van der Meer, Stephan Meijer, Hans Kristian Ploos van Amstel, Suzanne Polinder, Saskia E.M. Schols, Guus Wijfjes, Kees Kluft, Waander L. van Heerde, Geertje Goedhart, Carin Uyl, Jasmijn Timp, Anke Stekelenburg, Floor Moenen, Paula Ypma, Laurens Nieuwenhuizen, Arnoud Plat
Publikováno v:
Journal of Thrombosis and Haemostasis, 20(9), 2001-2011. Wiley
Journal of Thrombosis and Haemostasis, 20(9), 2001-2011. Wiley-Blackwell
Journal of thrombosis and haemostasis, 20(9), 2001-2011. Wiley-Blackwell
Journal of Thrombosis and Haemostasis, 20(9), 2001-2011. WILEY
Journal of Thrombosis and Haemostasis, 20(9), 2001-2011. Wiley-Blackwell Publishing Ltd
SYMPHONY consortium 2022, ' SYMPHONY consortium : Orchestrating personalized treatment for patients with bleeding disorders ', Journal of Thrombosis and Haemostasis, vol. 20, no. 9, pp. 2001-2011 . https://doi.org/10.1111/jth.15778
Journal of Thrombosis and Haemostasis, 20(9), 2001-2011. Wiley-Blackwell
Journal of thrombosis and haemostasis, 20(9), 2001-2011. Wiley-Blackwell
Journal of Thrombosis and Haemostasis, 20(9), 2001-2011. WILEY
Journal of Thrombosis and Haemostasis, 20(9), 2001-2011. Wiley-Blackwell Publishing Ltd
SYMPHONY consortium 2022, ' SYMPHONY consortium : Orchestrating personalized treatment for patients with bleeding disorders ', Journal of Thrombosis and Haemostasis, vol. 20, no. 9, pp. 2001-2011 . https://doi.org/10.1111/jth.15778
Background: Treatment choices for individual patients with an inborn bleeding disorder are increasingly challenging due to increasing options and rising costs for society. We have initiated an integrated interdisciplinary national research program. O
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f106600596b9764406a2984249fa8169
https://hdl.handle.net/1887/3494538
https://hdl.handle.net/1887/3494538