Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Alexander J. Winkle"'
Publikováno v:
MethodsX, Vol 7, Iss , Pp 100755- (2020)
Image processing and quantification is a routine and important task across disciplines in biomedical research. Understanding the effects of disease on the tissue and organ level often requires the use of images, however the process of interpreting th
Externí odkaz:
https://doaj.org/article/51ba065b1b324cdc9d4ab2c1f770fc6b
Autor:
Alexander J. Winkle, Drew M. Nassal, Rebecca Shaheen, Evelyn Thomas, Shivangi Mohta, Daniel Gratz, Seth H. Weinberg, Thomas J. Hund
Publikováno v:
Expert Opin Ther Targets
INTRODUCTION: Cardiac hypertrophy is associated with adverse outcomes across cardiovascular disease states. Despite strides over the last three decades in identifying molecular and cellular mechanisms driving hypertrophy, the link between pathophysio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b52fb0307cb0654a79d0f7290e88520
https://europepmc.org/articles/PMC8885901/
https://europepmc.org/articles/PMC8885901/
Publikováno v:
Cells, Vol 10, Iss 1516, p 1516 (2021)
Cells
Volume 10
Issue 6
Cells
Volume 10
Issue 6
The voltage-gated Na+ channel Nav1.5 is critical for normal cardiac myocyte excitability. Mathematical models have been widely used to study Nav1.5 function and link to a range of cardiac arrhythmias. There is growing appreciation for the importance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8290c841a36c3670c56d55e5dd5967e4
https://www.mdpi.com/2073-4409/10/6/1516
https://www.mdpi.com/2073-4409/10/6/1516
Publikováno v:
Modeling and Simulating Cardiac Electrical Activity ISBN: 9780750320641
Modeling and Simulating Cardiac Electrical Activity
Modeling and Simulating Cardiac Electrical Activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7ea97b63e69ec9172a0383721dff95a
https://doi.org/10.1088/978-0-7503-2064-1ch5
https://doi.org/10.1088/978-0-7503-2064-1ch5
Autor:
Nehal J. Patel, Evelyn Thomas, Thomas J. Hund, Alexander J. Winkle, Sathyadev Unudurthi, Daniel Gratz
Publikováno v:
Circulation Research. 125
Heart failure (HF) is a complex disease characterized by compromised cardiac structure and function. Previous work has identified a link between upregulation of pro-inflammatory cytokines, and HF. There is a critical need to gain better understanding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1850b94a5d0e9927fa0af8cbf43bd5d2
https://doi.org/10.1161/res.125.suppl_1.229
https://doi.org/10.1161/res.125.suppl_1.229
Autor:
Annu Panwar, Mirco Migliavacca, Jacob A. Nelson, José Cortés, Ana Bastos, Matthias Forkel, Alexander J. Winkler
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract While numerous studies report shifts in vegetation phenology, in this regard eddy covariance (EC) data, despite its continuous high-frequency observations, still requires further exploration. Furthermore, there is no general consensus on opt
Externí odkaz:
https://doaj.org/article/ac55d3be2e52478ca4f2f052828d3ac3
Autor:
Rackhun Son, Tobias Stacke, Veronika Gayler, Julia E. M. S. Nabel, Reiner Schnur, Lazaro Alonso, Christian Requena‐Mesa, Alexander J. Winkler, Stijn Hantson, Sönke Zaehle, Ulrich Weber, Nuno Carvalhais
Publikováno v:
Journal of Advances in Modeling Earth Systems, Vol 16, Iss 1, Pp n/a-n/a (2024)
Abstract Fire is a crucial factor in terrestrial ecosystems playing a role in disturbance for vegetation dynamics. Process‐based fire models quantify fire disturbance effects in stand‐alone dynamic global vegetation models (DGVMs) and their advan
Externí odkaz:
https://doaj.org/article/38b2fcd58de246c4a56699fc12f2b623
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-8 (2019)
The terrestrial biosphere absorbs a large fraction of emitted CO2, and thus, plays a critical role in climate change projections. Here, the authors use satellite leaf area and in-situ CO2 measurements to show that most Earth system models largely und
Externí odkaz:
https://doaj.org/article/952b70cdae804504a6df9b3157ead554
Autor:
Alexander J. Winkler, Jose Alfonso Dominguez-Nuñez, Inmaculada Aranaz, César Poza-Carrión, Katrina Ramonell, Shauna Somerville, Marta Berrocal-Lobo
Publikováno v:
Marine Drugs, Vol 15, Iss 2, p 40 (2017)
Chitin is the second most abundant biopolymer in nature after cellulose, and it forms an integral part of insect exoskeletons, crustacean shells, krill and the cell walls of fungal spores, where it is present as a high-molecular-weight molecule. In t
Externí odkaz:
https://doaj.org/article/1080e676f7564032bed6fc202faebb6b
Publikováno v:
Cells, Vol 10, Iss 6, p 1516 (2021)
The voltage-gated Na+ channel Nav1.5 is critical for normal cardiac myocyte excitability. Mathematical models have been widely used to study Nav1.5 function and link to a range of cardiac arrhythmias. There is growing appreciation for the importance
Externí odkaz:
https://doaj.org/article/441351a248df4b25a6fb400250e6da18