Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Alexander J. Watson"'
Publikováno v:
Cell Proliferation. 17:445-452
The intraperitoneal administration of large doses of quinacrine in rats results in a state of enteromegaly affecting mainly the distal small bowel, caecum and proximal colon. This enteromegaly is associated with mucosal crypt hyperplasia, and hypertr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8667ba3f8c520c970d37898a827d32aa
https://doi.org/10.1111/j.1365-2184.1984.tb00603.x
https://doi.org/10.1111/j.1365-2184.1984.tb00603.x
Publikováno v:
British medical journal. 3(5563)
Twenty-three female and 19 male patients were studied. Their ages ranged from 15 to 72 years. The total length of history of psoriasis ranged from 3 weeks to 50 years, and the duration of the most recent episode from 1 week to 20 years. All patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c957ead858205a5a28716717c01f381f
https://pubmed.ncbi.nlm.nih.gov/20791321
https://pubmed.ncbi.nlm.nih.gov/20791321
Autor:
O.F.W. James, H.C. Mitchison, Alexander J. Watson, Christopher O. Record, Margaret F. Bassendine, Jeremy M. Palmer
Publikováno v:
Journal of Hepatology. 15:336-344
The results of a 3-year, placebo-controlled trial of prednisolone treatment in primary biliary cirrhosis (PBC) are presented. The active (n = 19) and placebo (n = 17) arms were initially well matched for age, menopausal status and disease severity. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7242559eecf0f927cd1f5aa12c48cce
https://doi.org/10.1016/0168-8278(92)90065-w
https://doi.org/10.1016/0168-8278(92)90065-w
Publikováno v:
Cell proliferation. 31(2)
In a previous study we reported that the NSAID sulindac had a marked inhibitory effect on the development of colonic tumours in mice treated with the carcinogen 1,2‐dimethylhydrazine (DMH). In this study we examined the effects of sulindac in respe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37f43937bd5d99164bd6fcfa3d40b59a
https://pubmed.ncbi.nlm.nih.gov/9745616
https://pubmed.ncbi.nlm.nih.gov/9745616
Publikováno v:
Scopus-Elsevier
The in-vitro effects of hydroxyurea 5-FU and 5-FUdR have been extensively studied in experimental systems employing cell-line techniques. In this study we investigated the effects of these drugs on the levels of incorporation of labeled nucleosides i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4123c5336f66a021ef478c862b1db920
https://pubmed.ncbi.nlm.nih.gov/1748627
https://pubmed.ncbi.nlm.nih.gov/1748627
Autor:
Kathryn Elliott, K J Finney, Alexander J. Watson, Paul G. Ince, D R Appleton, Moganaden Moorghen
Publikováno v:
Carcinogenesis. 12(11)
An organ-culture system has been used to investigate the effect of certain gastrointestinal peptides on the morphology and cell proliferation of explants of azoxymethane (AOM)-treated colonic mucosa. Our aim was to ascertain whether such factors play
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33a79817d7f23af4ee0d3d87ad838baf
https://pubmed.ncbi.nlm.nih.gov/1934285
https://pubmed.ncbi.nlm.nih.gov/1934285
Autor:
James P. Sunter, Moganaden Moorghen, David R. Appleton, Paul G. Ince, Kathryn Elliott, Adrian L. Harris, Alexander J. Watson, K J Finney
Publikováno v:
Biochemical pharmacology. 41(8)
The in-vitro pharmacokinetics of vincristine (VCR) in normal rat colonic mucosa were studied. Two complementary approaches were adopted using an explant organ-culture system. Firstly [G-3H]vincristine (3HVCR) accumulation, retention and efflux were c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04ef3cccbe88d04a55c51c1441f7f0c3
https://pubmed.ncbi.nlm.nih.gov/2009097
https://pubmed.ncbi.nlm.nih.gov/2009097
Autor:
Jens F. Rehfeld, James Scott, Michael G. Bramble, L. Camassa, F. Rocca, Jens J. Hoist, Timothy J. Peters, J. Alexander-Williams, L. Sironi, Christopher O. Record, J.C. Paris, H. H. Dormeyer, P.A. Bianchi, H. Schönborn, W. Piubello, G. Cavallini, J.P. van de Merwe, A. Bozzani, K. H. Meyer zum Büschenfelde, Alexander J. Watson, G. Hess, C.P. Swain, Wilfred Niels Arnold, I. Vantini, D.W. Storey, Giorgio Brocco, O. V. Nielsen, Luigi Benini, Ludovico A. Scuro, M. van Blankenstein, Steen Lindkœr Jensen, P. Buchmann, L. Cominacini, J. S. Delmotte, V. Lo Cascio, E. Kolb, Joanne Wilson, P.R. Salmon, Dario Conte, P. Houcke, J. Knolle, J.M. Brunetaud, S.G. Bown
Publikováno v:
Digestion. 22:326-329
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d929b228d99fa9136dbe2b692aad005d
https://doi.org/10.1159/000198680
https://doi.org/10.1159/000198680
Publikováno v:
Digestion. 22:113-118
Liver tissue samples from 111 patients with various hepatic disorders including 37 with primary biliary cirrhosis (PBC) and 22 with chronic active hepatitis (CAH) were studied. Of the PBC patients, 33
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::597f9bb5c36dfccfa3c3b6406831e012
https://doi.org/10.1159/000198615
https://doi.org/10.1159/000198615
Publikováno v:
British Journal of Cancer
A morphological method has been developed allowing measurement of the effect on intestinal epithelia of vincristine. In routinely prepared tissue sections the proportion of mitotic events progressing beyond metaphase is counted by microscopy. When es
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f720c2f144f22fbb054aea241d84289
https://doi.org/10.1038/bjc.1988.80
https://doi.org/10.1038/bjc.1988.80