Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Alexander J. Oelke"'
Publikováno v:
Angewandte Chemie. 122:6275-6278
Publikováno v:
ChemInform. 43
A variety of silyl-substituted propargylic carbonates are coupled with arylzinc iodides in the presence of a nickel/chiral bis(oxazolinyl)pyridine catalyst to give the arylated alkynes with up to 93% enantioselectivity.
To date, effective nickel-catalyzed enantioselective cross-couplings of alkyl electrophiles that bear oxygen leaving groups have been limited to reactions of allylic alcohol derivatives with Grignard reagents. In this Communication, we establish that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4918d2b356df36d543fb248a69274a77
https://resolver.caltech.edu/CaltechAUTHORS:20200428-095145561
https://resolver.caltech.edu/CaltechAUTHORS:20200428-095145561
Publikováno v:
ChemInform. 42
Since their first discovery in 1959, natural products containing the piperazic acid motif have been isolated from a variety of sources and exhibit diverse biological activity profiles. This review provides information about their isolation and biolog
Publikováno v:
Natural product reports. 28(8)
Since their first discovery in 1959, natural products containing the piperazic acid motif have been isolated from a variety of sources and exhibit diverse biological activity profiles. This review provides information about their isolation and biolog
Autor:
Alexander J. Oelke, Francesca Antonietti, Leonardo Bertone, Philippa B. Cranwell, David J. France, Rebecca J. M. Goss, Tatjana Hofmann, Stephan Knauer, Steven J. Moss, Paul C. Skelton, Richard M. Turner, Georg Wuitschik, Steven V. Ley
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 17(15)
Here we describe in full our investigations into the synthesis of the dimeric cyclohexapeptide chloptosin in 17 linear steps. Particularly, this work features an organocatalytic tandem process for the synthesis of the embedded piperazic acids, in whi
Autor:
Veit Wascholowski, Vilius Franckevicius, Sirirat Kumarn, Deborah A. Longbottom, Steven V. Ley, Alexander J. Oelke
Publikováno v:
ChemInform. 40
Publikováno v:
ChemInform. 38
A sequential, organocatalysed asymmetric reaction to access chiral 1,2-oxazines and chiral pyridazines is reported, which proceeds in moderate to good yields and good to excellent enantioselectivities.
Publikováno v:
ChemInform. 38
Here we describe a highly enantioselective organocatalytic synthesis of chiral 3,6-dihydropyridazines from achiral starting materials which proceeds with good yield via a one-pot procedure.