Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Alexander J. Neil"'
Publikováno v:
Gynecologic Oncology Reports, Vol 48, Iss , Pp 101237- (2023)
Patients with advanced stage or recurrent mucinous ovarian carcinoma exhibit poor response to standard platinum- and taxane-based chemotherapy and poor prognosis. We report a 29-year-old patient with recurrent ERBB2-amplified mucinous ovarian carcino
Externí odkaz:
https://doaj.org/article/14440632f14748219cf1e8d145c428d8
Autor:
Susan E. Tsutakawa, Mark J. Thompson, Andrew S. Arvai, Alexander J. Neil, Steven J. Shaw, Sana I. Algasaier, Jane C. Kim, L. David Finger, Emma Jardine, Victoria J.B. Gotham, Altaf H. Sarker, Mai Z. Her, Fahad Rashid, Samir M. Hamdan, Sergei M. Mirkin, Jane A. Grasby, John A. Tainer
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Flap Endonuclease 1 is a DNA replication and repair enzyme indispensable for maintaining genomic stability. Here the authors provide mechanistic details on how FEN1 selects for 5′-flaps and promotes catalysis to avoid large-scale repeat expansion b
Externí odkaz:
https://doaj.org/article/7d8f8666ae664b27be8155fb17c1e260
Autor:
Andres Santos, Madeline Sauer, Alexander J. Neil, Isaac H. Solomon, Jason L. Hornick, Drucilla J. Roberts, Bradley J. Quade, Carlos Parra-Herran
Publikováno v:
Modern Pathology. 35:1175-1180
Current public health initiatives to contain the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) global pandemic focus on expanding vaccination efforts to include vulnerable populations such as pregnant people. Vaccines using messenger r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::faa45844269246c6a9f372b65c84bc5c
https://doi.org/10.1038/s41379-022-01061-3
https://doi.org/10.1038/s41379-022-01061-3
Autor:
Alexander J. Neil, Lei Zhao, Raymond A. Isidro, Amitabh Srivastava, James M. Cleary, Fei Dong
Publikováno v:
Modern Pathology. 36:100183
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::591cd0615d5a6b08372840113f75fcf3
https://doi.org/10.1016/j.modpat.2023.100183
https://doi.org/10.1016/j.modpat.2023.100183
Publikováno v:
Histopathology. 79:444-448
Primary adenocarcinoma of the seminal vesicle is very rare, with fewer than one hundred well-documented cases reported in the literature (1). These tumors have variable microscopic appearances, including cases with hobnail, polygonal and columnar neo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::393e8277fb2a935d4647e83d1a6a67e3
https://doi.org/10.1111/his.14425
https://doi.org/10.1111/his.14425
Autor:
Alexandra N. Khristich, Julia A. Hisey, Ryan J. McGinty, Sergei M. Mirkin, Alexander J. Neil, Marcin Hitczenko, Ishtiaque Quasem
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance The inheritance of long (GAA)n repeats in the frataxin gene causes the debilitating neurodegenerative disease Friedreich’s ataxia. Subsequent expansions of these repeats throughout a patient’s lifetime in the affected tissues, like t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c4e5eee445ee6038efc4a2f3dd38414
http://europepmc.org/articles/PMC7865128
http://europepmc.org/articles/PMC7865128
Autor:
Margaret Dominska, Thomas D. Petes, Alexander J. Neil, Rachel G. Rubinstein, Sergei M. Mirkin, Ryan J. McGinty, Denis A. Kiktev
Publikováno v:
Genome Research. 27:2072-2082
Improper DNA double-strand break (DSB) repair results in complex genomic rearrangements (CGRs) in many cancers and various congenital disorders in humans. Trinucleotide repeat sequences, such as (GAA)n repeats in Friedreich's ataxia, (CTG)n repeats i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3372f6101a3bf4eb031689101205076c
https://doi.org/10.1101/gr.228148.117
https://doi.org/10.1101/gr.228148.117
Publikováno v:
Nucleic Acids Research
Expansion of simple DNA repeats is responsible for numerous hereditary diseases in humans. The role of DNA replication, repair and transcription in the expansion process has been well documented. Here we analyzed, in a yeast experimental system, the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::615b0be6d76080bcac0cdfb866ef805d
https://pubmed.ncbi.nlm.nih.gov/29447396
https://pubmed.ncbi.nlm.nih.gov/29447396