Data quality predicts care quality: findings from a national clinical audit

Autor: Mark Yates, Katie Bechman, Elaine M. Dennison, Alexander J. MacGregor, Jo Ledingham, Sam Norton, James B. Galloway

Publikováno v: Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-8 (2020)

Abstract Background Missing clinical outcome data are a common occurrence in longitudinal studies. Data quality in clinical audit is a particular cause for concern. The relationship between departmental levels of missing clinical outcome data and car

Externí odkaz: https://doaj.org/article/9a478260346846e09917c1fdebf6dfb0

Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arthritis

Autor: Kazuyoshi, Ishigaki, Saori, Sakaue, Chikashi, Terao, Yang, Luo, Kyuto, Sonehara, Kensuke, Yamaguchi, Tiffany, Amariuta, Chun Lai, Too, Vincent A, Laufer, Ian C, Scott, Sebastien, Viatte, Meiko, Takahashi, Koichiro, Ohmura, Akira, Murasawa, Motomu, Hashimoto, Hiromu, Ito, Mohammed, Hammoudeh, Samar Al, Emadi, Basel K, Masri, Hussein, Halabi, Humeira, Badsha, Imad W, Uthman, Xin, Wu, Li, Lin, Ting, Li, Darren, Plant, Anne, Barton, Gisela, Orozco, Suzanne M M, Verstappen, John, Bowes, Alexander J, MacGregor, Suguru, Honda, Masaru, Koido, Kohei, Tomizuka, Yoichiro, Kamatani, Hiroaki, Tanaka, Eiichi, Tanaka, Akari, Suzuki, Yuichi, Maeda, Kenichi, Yamamoto, Satoru, Miyawaki, Gang, Xie, Jinyi, Zhang, Christopher I, Amos, Edward, Keystone, Gertjan, Wolbink, Irene, van der Horst-Bruinsma, Jing, Cui, Katherine P, Liao, Robert J, Carroll, Hye-Soon, Lee, So-Young, Bang, Katherine A, Siminovitch, Niek, de Vries, Lars, Alfredsson, Solbritt, Rantapää-Dahlqvist, Elizabeth W, Karlson, Sang-Cheol, Bae, Robert P, Kimberly, Jeffrey C, Edberg, Xavier, Mariette, Tom, Huizinga, Philippe, Dieudé, Matthias, Schneider, Martin, Kerick, Joshua C, Denny, Koichi, Matsuda, Keitaro, Matsuo, Tsuneyo, Mimori, Fumihiko, Matsuda, Keishi, Fujio, Yoshiya, Tanaka, Atsushi, Kumanogoh, Matthew, Traylor, Cathryn M, Lewis, Stephen, Eyre, Huji, Xu, Richa, Saxena, Thurayya, Arayssi, Yuta, Kochi, Katsunori, Ikari, Masayoshi, Harigai, Peter K, Gregersen, Kazuhiko, Yamamoto, S, Louis Bridges, Leonid, Padyukov, Javier, Martin, Lars, Klareskog, Yukinori, Okada, Soumya, Raychaudhuri

Publikováno v: Nature Genetics, 54, 1640-1651
The Biobank Japan Project 2022, ' Multi-ancestry genome-wide association analyses identify novel genetic mechanisms in rheumatoid arthritis ', Nature Genetics, vol. 54, no. 11, pp. 1640-1651 . https://doi.org/10.1038/s41588-022-01213-w
Nature genetics, 54(11), 1640-1651. Nature Publishing Group
Nature Genetics, 54(11), 1640-+. NATURE PORTFOLIO
Nature Genetics, 54(11), 1640-1651. Nature Publishing Group
Nature Genetics, 54, 11, pp. 1640-1651
Nat Genet

Multi-ancestry genome-wide association analyses identify 124 risk loci for rheumatoid arthritis, of which 34 are novel. A polygenic risk score based on multi-ancestry data showed comparable performance between populations of European and East Asian a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2e48733cf2e8205acbde830a39b0265
https://doi.org/10.1038/s41588-022-01213-w

Impact of comorbidities on the safety and effectiveness of hip and knee arthroplasty surgery

Autor: Bélène, Podmore, Andrew, Hutchings, John A, Skinner, Alexander J, MacGregor, Jan, van der Meulen

Publikováno v: The bonejoint journal. (1)

Access to joint replacement is being restricted for patients with comorbidities in a number of high-income countries. However, there is little evidence on the impact of comorbidities on outcomes. The purpose of this study was to determine the safety

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::2622d4ad1a94260b50028639626d88b4
https://pubmed.ncbi.nlm.nih.gov/33380188

Glucocorticoid withdrawal in polymyalgia rheumatica: the theory versus the practice

Autor: Max, Yates, Richard A, Watts, Francesca, Swords, Alexander J, MacGregor

Publikováno v: Clinical and experimental rheumatology. 35(1)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::649d8129a94153b7d1ad2f9bcb9ab1fc
https://pubmed.ncbi.nlm.nih.gov/28079505

HLA-DRB1 Amino Acid Positions 11/13, 71, and 74 Are Associated With Inflammation Level, Disease Activity, and the Health Assessment Questionnaire Score in Patients With Inflammatory Polyarthritis

Autor: Ling, Stephanie, Viatte, Sebastien, Lunt, Mark, Van Sijl , Alper M., Silva-Fernandez, Lucia, Symmons, Deborah, Young, Adam, Alexander J. Macgregor, Barton, Anne

Publikováno v: RUNA. Repositorio da Consellería de Sanidade e Sergas
Servizo Galego de Saúde (SERGAS)
Arthritis & Rheumatology (Hoboken, N.j.)
Ling, S, Viatte, S, Lunt, M, Van Sijl, A M, Silva-Fernandez, L, Symmons, D, Young, A, Alexander J. Macgregor, & Barton, A 2016, ' HLA–DRB1 Amino Acid Positions 11/13, 71, and 74 Are Associated With Inflammation Level, Disease Activity, and the Health Assessment Questionnaire Score in Patients With Inflammatory Polyarthritis ', Arthritis and Rheumatology, vol. 68, no. 11, pp. 2618-2628 . https://doi.org/10.1002/art.39780

Rheumatoid arthritis (RA) susceptibility HLA-DRB1 haplotypes based on amino acid positions 11/13, 71, and 74 predict radiographic damage. The mechanism of action is unknown, but it may be mediated by inflammation. We undertook this study to systemati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::6673972510b200342da83c191a0cea96
http://hdl.handle.net/20.500.11940/9562