Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Alexander J. He"'
Autor:
Lion F. K. Uhl, Han Cai, Sophia L. Oram, Jagdish N. Mahale, Andrew J. MacLean, Julie M. Mazet, Theo Piccirilli, Alexander J. He, Doreen Lau, Tim Elliott, Audrey Gerard
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Effective responses to intracellular pathogens are characterized by T cell clones with a broad affinity range for their cognate peptide and diverse functional phenotypes. How T cell clones are selected throughout the response to retain a bre
Externí odkaz:
https://doaj.org/article/93ce11988e134251aa03f8a54f6cf7df
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Both infectious viral diseases and cancer have historically been some of the most common causes of death worldwide. The COVID-19 pandemic is a decidedly relevant example of the former. Despite progress having been made over past decades, new and impr
Externí odkaz:
https://doaj.org/article/d8090fa0f8c641eebda01348de1d1e78
Autor:
Lion F.K. Uhl, Han Cai, Jagdish N. Mahale, Andrew J. MacLean, Julie M. Mazet, Alexander J. He, Doreen Lau, Tim Elliott, Audrey Gerard
The most effective responses to intracellular pathogens have a breadth of T-cell clones with different affinities for their cognate peptide, and a diversity of functional phenotypes, from effector to long-lived memory cells. While high- and low-affin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2656462f929355dd1e1fe6dd8cd24785
https://doi.org/10.1101/2023.03.06.531375
https://doi.org/10.1101/2023.03.06.531375
Autor:
Sam C. Scholten, Priya Singh, Alexander J. Healey, Islay O. Robertson, Galya Haim, Cheng Tan, David A. Broadway, Lan Wang, Hiroshi Abe, Takeshi Ohshima, Mehran Kianinia, Philipp Reineck, Igor Aharonovich, Jean-Philippe Tetienne
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-8 (2024)
Abstract Optically addressable spin defects hosted in two-dimensional van der Waals materials represent a new frontier for quantum technologies, promising to lead to a new class of ultrathin quantum sensors and simulators. Recently, hexagonal boron n
Externí odkaz:
https://doaj.org/article/877819cbefe8475a9d3659c0a5d66613
Autor:
Cristina Melero, S. Jimmy Budiardjo, Anahita Daruwalla, Lance Larrabee, Oleg Ganichkin, Alexander J. Heiler, Jill Fenaux, Ben Chung, Germaine Fuh, Yao-Ming Huang
Publikováno v:
mAbs, Vol 16, Iss 1 (2024)
Human CD200R1 (hCD200R1), an immune inhibitory receptor expressed predominantly on T cells and myeloid cells, was identified as a promising immuno-oncology target by the 23andMe database. Blockade of CD200R1-dependent signaling enhances T cell-mediat
Externí odkaz:
https://doaj.org/article/c523efc8d50249edacd1a4181307eaa0
Autor:
Katja Brand, Toby Wise, Alexander J. Hess, Bruce R. Russell, Klaas E. Stephan, Olivia K. Harrison
Publikováno v:
Frontiers in Psychology, Vol 15 (2024)
IntroductionInteroception, the perception of the internal state of the body, has been shown to be closely linked to emotions and mental health. Of particular interest are interoceptive learning processes that capture associations between environmenta
Externí odkaz:
https://doaj.org/article/8fce3319068a4cb0823aaf9699543051
Autor:
Jeehyun Park, Ilse Gantois, Arkady Khoutorsky, Agnieszka Skalecka, Nahum Sonenberg, Alexander J. He, Vinh Tai Truong, Shane Wiebe, Anmol Nagpal, Karine Gamache
Translational control plays a key role in regulation of neuronal activity and behavior. Deletion of the translational repressor 4E-BP2 in mice alters excitatory and inhibitory synaptic functions, engendering autistic-like behaviors. The contribution
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a159fb9eebca184bde8b08ee4a53e1f7
https://europepmc.org/articles/PMC6731681/
https://europepmc.org/articles/PMC6731681/
Autor:
Efraín Duarte, Erick Zagal, Juan A. Barrera, Francis Dube, Fabio Casco, Alexander J. Hernández
Publikováno v:
European Journal of Remote Sensing, Vol 55, Iss 1, Pp 213-231 (2022)
Mapping the spatial distribution of soil organic carbon (SOC) in lands covered by tropical forests is important to understand the relationship and dynamics of SOC in this type of ecosystem. In this study, the Random Forest (RF) algorithm was used to
Externí odkaz:
https://doaj.org/article/910c6d31c0774751a71818534ff1dffa
Autor:
Sophie A. Herbst, Mattias Vesterlund, Alexander J. Helmboldt, Rozbeh Jafari, Ioannis Siavelis, Matthias Stahl, Eva C. Schitter, Nora Liebers, Berit J. Brinkmann, Felix Czernilofsky, Tobias Roider, Peter-Martin Bruch, Murat Iskar, Adam Kittai, Ying Huang, Junyan Lu, Sarah Richter, Georgios Mermelekas, Husen Muhammad Umer, Mareike Knoll, Carolin Kolb, Angela Lenze, Xiaofang Cao, Cecilia Österholm, Linus Wahnschaffe, Carmen Herling, Sebastian Scheinost, Matthias Ganzinger, Larry Mansouri, Katharina Kriegsmann, Mark Kriegsmann, Simon Anders, Marc Zapatka, Giovanni Del Poeta, Antonella Zucchetto, Riccardo Bomben, Valter Gattei, Peter Dreger, Jennifer Woyach, Marco Herling, Carsten Müller-Tidow, Richard Rosenquist, Stephan Stilgenbauer, Thorsten Zenz, Wolfgang Huber, Eugen Tausch, Janne Lehtiö, Sascha Dietrich
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Proteomics can be used to refine cancer classification. Here, the authors characterise chronic lymphocytic leukaemia patients by proteogenomics, and identified a subtype of patients with poor prognosis associated with aberrant B cell receptor signall
Externí odkaz:
https://doaj.org/article/91f1d089720c4b3a86f1c0a1195a3faa
Publikováno v:
Fire, Vol 6, Iss 12, p 474 (2023)
In wildland–urban interface areas, firefighters balance wildfire suppression and structure protection. These tasks are often performed under resource limitations, especially when many structures are at risk. To address this problem, wildland firefi
Externí odkaz:
https://doaj.org/article/5e357bc3e29542e880bfcc180cd8a992