Zobrazeno 1 - 10
of 81
pro vyhledávání: '"Alexander J. Hartemink"'
Publikováno v:
Genome Biology, Vol 18, Iss 1, Pp 1-19 (2017)
Abstract Single cell experimental techniques reveal transcriptomic and epigenetic heterogeneity among cells, but how these are related is unclear. We present MATCHER, an approach for integrating multiple types of single cell measurements. MATCHER use
Externí odkaz:
https://doaj.org/article/71449ce294ab45cd8643b94b03412705
Publikováno v:
bioRxiv
Proper maintenance of epigenetic information after replication is dependent on the rapid assembly and maturation of chromatin. Chromatin Assembly Complex 1 (CAF-1) is a conserved histone chaperone that deposits (H3-H4)2tetramers as part of the replic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62d7dc24bafc493ad16ce8437894d576
https://doi.org/10.1101/2023.05.25.541209
https://doi.org/10.1101/2023.05.25.541209
Autor:
Kaixuan Luo, Jianling Zhong, Alexias Safi, Linda K. Hong, Alok K. Tewari, Lingyun Song, Timothy E. Reddy, Li Ma, Gregory E. Crawford, Alexander J. Hartemink
Publikováno v:
Genome Research. 32:1183-1198
Over a thousand different transcription factors (TFs) bind with varying occupancy across the human genome. Chromatin immunoprecipitation (ChIP) can assay occupancy genome-wide, but only one TF at a time, limiting our ability to comprehensively observ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c3af9d47d6c2750ddf9dbea7d7e8d7b
https://doi.org/10.1101/gr.272203.120
https://doi.org/10.1101/gr.272203.120
Publikováno v:
Nucleic Acids Research
Chromatin is a tightly packaged structure of DNA and protein within the nucleus of a cell. The arrangement of different protein complexes along the DNA modulates and is modulated by gene expression. Measuring the binding locations and occupancy level
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d5d19380d7ca75d3a09df97d5744766
https://doi.org/10.1093/nar/gkab553
https://doi.org/10.1093/nar/gkab553
Autor:
Sneha Mitra, Trung Q. Tran, Alexander J. Hartemink, David M. MacAlpine, Vinay Tripuraneni, Heather K. MacAlpine
Publikováno v:
Genome Res
Though the sequence of the genome within each eukaryotic cell is essentially fixed, it exists within a complex and changing chromatin state. This state is determined, in part, by the dynamic binding of proteins to the DNA. These proteins—including
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca4f4ccba69880bda725d38f3fb5c2d7
https://doi.org/10.1101/gr.267237.120
https://doi.org/10.1101/gr.267237.120
Publikováno v:
Genes, Vol 12, Iss 1998, p 1998 (2021)
Genes
Genes; Volume 12; Issue 12; Pages: 1998
Genes
Genes; Volume 12; Issue 12; Pages: 1998
Origins of DNA replication are specified by the ordered recruitment of replication factors in a cell-cycle–dependent manner. The assembly of the pre-replicative complex in G1 and the pre-initiation complex prior to activation in S phase are well ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::087c74983a1372da65992f95361b4a68
https://www.mdpi.com/2073-4425/12/12/1998
https://www.mdpi.com/2073-4425/12/12/1998
Publikováno v:
Res Comput Mol Biol
Lecture Notes in Computer Science ISBN: 9783030452568
RECOMB
Lecture Notes in Computer Science ISBN: 9783030452568
RECOMB
Chromatin is the tightly packaged structure of DNA and protein within the nucleus of a cell. The arrangement of different protein complexes along the DNA modulates and is modulated by gene expression. Measuring the binding locations and level of occu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37b7f2563226bfc3b22ba6a6937809b0
https://pubmed.ncbi.nlm.nih.gov/34386808
https://pubmed.ncbi.nlm.nih.gov/34386808
Autor:
Vinay Tripuraneni, Gonen Memisoglu, James E. Haber, Wei Zhu, Heather K. MacAlpine, Alexander J. Hartemink, Trung Q. Tran, David M. MacAlpine
Publikováno v:
Genome Res
We interrogated at nucleotide resolution the spatiotemporal order of chromatin changes that occur immediately following a site-specific double-strand break (DSB) upstream of the PHO5 locus and its subsequent repair by nonhomologous end joining (NHEJ)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a961d788a53724148874c24423394466
https://europepmc.org/articles/PMC8092003/
https://europepmc.org/articles/PMC8092003/
Autor:
Jianling Zhong, Timothy E. Reddy, Alexias Safi, Alexander J. Hartemink, Gregory E. Crawford, Li Ma, Linda K. Hong, Kaixuan Luo, Lingyun Song, Alok K. Tewari
Over a thousand different transcription factors (TFs) bind with varying occupancy across the human genome. Chromatin immunoprecipitation (ChIP) can assay occupancy genome-wide, but only one TF at a time, limiting our ability to comprehensively observ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36e1a9e4d4cfff8ec047790a2c4dfa44
https://doi.org/10.1101/2020.06.28.171587
https://doi.org/10.1101/2020.06.28.171587
Autor:
Alexander J. Hartemink, Trung Q. Tran, Vinay Tripuraneni, David M. MacAlpine, James E. Haber, Gonen Memisoglu, Wei Zhu
Although the molecular events required for the repair of double-strand breaks (DSB) have been well characterized, the role of epigenetic processes in the recognition and repair of DSBs has only been investigated at low resolution. We rapidly and sync
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5898119df16fcfd68cf143b6b1e5cce8