Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Alexander J. Ehrenberg"'
Autor:
Alexander J. Ehrenberg, Ayesha Khatun, Emma Coomans, Matthew J. Betts, Federica Capraro, Elisabeth H. Thijssen, Konstantin Senkevich, Tehmina Bharucha, Mehrsa Jafarpour, Peter N. E. Young, William Jagust, Stephen F. Carter, Tammaryn Lashley, Lea T. Grinberg, Joana B. Pereira, Niklas Mattsson-Carlgren, Nicholas J. Ashton, Jörg Hanrieder, Henrik Zetterberg, Michael Schöll, Ross W. Paterson
Publikováno v:
Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-11 (2020)
Abstract Background The panel of fluid- and imaging-based biomarkers available for neurodegenerative disease research is growing and has the potential to close important gaps in research and the clinic. With this growth and increasing use, appropriat
Externí odkaz:
https://doaj.org/article/ee2fb1323ee1493ca8afceec7fcc54ce
Publikováno v:
Epidemics, Vol 37, Iss , Pp 100527- (2021)
The high proportion of transmission events derived from asymptomatic or presymptomatic infections make SARS-CoV-2, the causative agent in COVID-19, difficult to control through the traditional non-pharmaceutical interventions (NPIs) of symptom-based
Externí odkaz:
https://doaj.org/article/ff101cfbcf304bc69f268905fabdb3cb
Autor:
Jennifer R. Hamilton, Elizabeth C. Stahl, Connor A. Tsuchida, Enrique Lin-Shiao, C. Kimberly Tsui, Kathleen Pestal, Holly K. Gildea, Lea B. Witkowsky, Erica A. Moehle, Shana L. McDevitt, Matthew McElroy, Amanda Keller, Iman Sylvain, Ariana Hirsh, Alison Ciling, Alexander J. Ehrenberg, Bradley R. Ringeisen, Garth Huberty, Fyodor D. Urnov, Petros Giannikopoulos, Jennifer A. Doudna, IGI SARS-CoV-2 Consortium
Publikováno v:
PLoS ONE, Vol 16, Iss 8 (2021)
Saliva is an attractive specimen type for asymptomatic surveillance of COVID-19 in large populations due to its ease of collection and its demonstrated utility for detecting RNA from SARS-CoV-2. Multiple saliva-based viral detection protocols use a d
Externí odkaz:
https://doaj.org/article/250fe7c14c81427f8666bd5d2e84261b
Autor:
Elizabeth C. Stahl, Allan R. Gopez, Connor A. Tsuchida, Vinson B. Fan, Erica A. Moehle, Lea B. Witkowsky, Jennifer R. Hamilton, Enrique Lin-Shiao, Matthew McElroy, Shana L. McDevitt, Alison Ciling, C. Kimberly Tsui, Kathleen Pestal, Holly K. Gildea, Amanda Keller, Iman A. Sylvain, Clara Williams, Ariana Hirsh, Alexander J. Ehrenberg, Rose Kantor, Matthew Metzger, Kara L. Nelson, Fyodor D. Urnov, Bradley R. Ringeisen, Petros Giannikopoulos, Jennifer A. Doudna, IGI Testing Consortium
Publikováno v:
PLoS ONE, Vol 16, Iss 11 (2021)
Clinical and surveillance testing for the SARS-CoV-2 virus relies overwhelmingly on RT-qPCR-based diagnostics, yet several popular assays require 2–3 separate reactions or rely on detection of a single viral target, which adds significant time, cos
Externí odkaz:
https://doaj.org/article/8b3699807c8348d7aa2a3fafef2c5562
Autor:
Alexander J. Ehrenberg, Ayesha Khatun, Emma Coomans, Matthew J. Betts, Federica Capraro, Elisabeth H. Thijssen, Konstantin Senkevich, Tehmina Bharucha, Mehrsa Jafarpour, Peter N. E. Young, William Jagust, Stephen F. Carter, Tammaryn Lashley, Lea T. Grinberg, Joana B. Pereira, Niklas Mattsson-Carlgren, Nicholas J. Ashton, Jörg Hanrieder, Henrik Zetterberg, Michael Schöll, Ross W. Paterson
Publikováno v:
Alzheimer’s Research & Therapy, Vol 12, Iss 1, Pp 1-1 (2020)
An amendment to this paper has been published and can be accessed via the original article.
Externí odkaz:
https://doaj.org/article/9d2e708c772146abb1731ccc8f99bc1a
Publikováno v:
Frontiers in Neuroscience, Vol 12 (2018)
Externí odkaz:
https://doaj.org/article/92a3ce05442242ea86c1a589c01df1e5
Autor:
Alexander J. Ehrenberg, Michael A. Kelberman, Kathy Y. Liu, Martin J. Dahl, David Weinshenker, Neus Falgàs, Shubir Dutt, Mara Mather, Mareike Ludwig, Matthew J. Betts, Joseph R. Winer, Stefan Teipel, Alexandra J. Weigand, Oxana Eschenko, Dorothea Hämmerer, Marina Leiman, Scott E. Counts, James M. Shine, Ian H. Robertson, Allan I. Levey, Elisa Lancini, Gowoon Son, Christoph Schneider, Maxime Van Egroo, Claudio Liguori, Qin Wang, Elena M. Vazey, Federico Rodriguez‐Porcel, Lena Haag, Mark W. Bondi, Sven Vanneste, Whitney M. Freeze, Yeo‐Jin Yi, Mihovil Maldinov, Jennifer Gatchel, Abhijit Satpati, Claudio Babiloni, William S. Kremen, Robert Howard, Heidi I. L. Jacobs, Lea T. Grinberg
Publikováno v:
Alzheimer's and dementia 19(5), 2182-2196 (2023). doi:10.1002/alz.12937
Alzheimer's & Dementia. Elsevier Science
Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring
Alzheimer's & Dementia
Alzheimer's & Dementia. Elsevier Science
Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring
Alzheimer's & Dementia
The neuromodulatory subcortical system (NSS) nuclei are critical hubs for survival, hedonic tone, and homeostasis. Tau-associated NSS degeneration occurs early in Alzheimer's disease (AD) pathogenesis, long before the emergence of pathognomonic memor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04a0b4d3a400aa29fe8f0dc7c1ee7078
https://pub.dzne.de/record/194973
https://pub.dzne.de/record/194973
Autor:
Caroline Lew, Salvatore Spina, Lea T. Grinberg, Alexander J. Ehrenberg, William W. Seeley, Helmut Heinsen, Kenneth S. Kosik, Israel Hernandez, Martin Kampmann, Bruce L. Miller, Kun Leng, Kaitlyn N. Letourneau
Publikováno v:
Acta Neuropathol
The farnesyltransferase inhibitor, Lonafarnib, reduces tau inclusions and associated atrophy in familial tauopathy models through activation of autophagy, mediated by the inhibition of farnesylation of the Ras GTPase, Rhes. While hinting at a role of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f639668bd4a1dd3a679f71bc65db953d
https://doi.org/10.1007/s00401-021-02279-2
https://doi.org/10.1007/s00401-021-02279-2
Autor:
William W. Seeley, Gabor G. Kovacs, Eun-Joo Kim, Lorenzo Pasquini, Joel H. Kramer, Kevin Wojta, Salvatore Spina, Suzee E. Lee, Anna Karydas, Claudia K. Suemoto, Elisa de Paula França Resende, Jorge J. Llibre-Guerra, Bruce L. Miller, Isabel E. Allen, Shirley Yin-Yu Pang, Eliana Marisa Ramos, Ji Hye Hwang, Alexander J. Ehrenberg, Adam M. Staffaroni, Lea T. Grinberg
Publikováno v:
Brain Pathol
BACKGROUND: Polymorphisms in TMEM106B, a gene on chromosome 7p21.3 involved in lysosomal trafficking, correlates to worse neuropathological and clinical outcomes in frontotemporal lobar degeneration (FTLD) and amyotrophic lateral sclerosis (ALS) with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a22478d31c0809a72a5a7b3dd7df5b8
https://doi.org/10.1111/bpa.12924
https://doi.org/10.1111/bpa.12924
Autor:
Martin Kampmann, Song Hua Li, Norma Neff, William W. Seeley, Renata Elaine Paraizo Leite, Rene Sit, Antonia M. H. Piergies, Claudia K. Suemoto, Michelle Tan, Rana Eser, Carlos Augusto Pasqualucci, Lea T. Grinberg, Kun Leng, Roberta Diehl Rodriguez, Alexander J. Ehrenberg, Helmut Heinsen, Emmy Li, Salvatore Spina
Publikováno v:
Nature Neuroscience. 24:276-287
Alzheimer's disease (AD) is characterized by the selective vulnerability of specific neuronal populations, the molecular signatures of which are largely unknown. To identify and characterize selectively vulnerable neuronal populations, we used single
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ef733181b19ed0bc32a32a609dbc034
https://doi.org/10.1038/s41593-020-00764-7
https://doi.org/10.1038/s41593-020-00764-7