Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Alexander J. Craig"'
Autor:
Birthe Meineke, Johannes Heimgärtner, Alexander J. Craig, Michael Landreh, Lindon W. K. Moodie, Simon J. Elsässer
Publikováno v:
Frontiers in Chemistry, Vol 9 (2021)
Bioorthogonal chemistry allows rapid and highly selective reactivity in biological environments. The copper-catalyzed azide–alkyne cycloaddition (CuAAC) is a classic bioorthogonal reaction routinely used to modify azides or alkynes that have been i
Externí odkaz:
https://doaj.org/article/80dfbc6fdcfb4fc3aa01db18bc5f6838
Autor:
Alexander J. Craig, Yuri Ermolovich, Alan Cameron, Agnes Rodler, Helen Wang, Jeffrey A. Hawkes, Madlen Hubert, Fredrik Björkling, Natalia Molchanova, Margaret A. Brimble, Lindon W. K. Moodie, Johan Svenson
Publikováno v:
ACS Medicinal Chemistry Letters.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27fb0676a4d665e4a9a3f9a74bd62623
https://doi.org/10.1021/acsmedchemlett.3c00093
https://doi.org/10.1021/acsmedchemlett.3c00093
Publikováno v:
The Journal of Organic Chemistry. 85:5486-5492
The mechanism of the reaction between cyclopropyl acid chlorides and imines to form 1,3-oxazin-4-enones was probed through physical and computational experiments. The data gathered strongly support the reaction proceeding through an N-acyl iminium in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0075ce912cbf7801ca7490724ff2f18
https://doi.org/10.1021/acs.joc.0c00229
https://doi.org/10.1021/acs.joc.0c00229
Autor:
Andreas Luttens, Hjalmar Gullberg, Eldar Abdurakhmanov, Duy Duc Vo, Dario Akaberi, Vladimir O. Talibov, Natalia Nekhotiaeva, Laura Vangeel, Steven De Jonghe, Dirk Jochmans, Janina Krambrich, Ali Tas, Bo Lundgren, Ylva Gravenfors, Alexander J. Craig, Yoseph Atilaw, Anja Sandström, Lindon W. K. Moodie, Åke Lundkvist, Martijn J. van Hemert, Johan Neyts, Johan Lennerstrand, Jan Kihlberg, Kristian Sandberg, U. Helena Danielson, Jens Carlsson
Publikováno v:
Journal of the American Chemical Society, 144(7), 2905-2920. AMER CHEMICAL SOC
Drugs targeting SARS-CoV-2 could have saved millions of lives during the COVID-19 pandemic, and it is now crucial to develop inhibitors of coronavirus replication in preparation for future outbreaks. We explored two virtual screening strategies to fi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::946c3c3e10aa0c690988b970c049d161
http://hdl.handle.net/1887/3479854
http://hdl.handle.net/1887/3479854
Autor:
Bill C. Hawkins, Alexander J. Craig
Publikováno v:
Synthesis. 52:27-39
The cyclopropane functionality has been exploited in a myriad of settings that range from total synthesis and methodological chemistry, to medical and materials science. While it has been seen in such a breadth of settings, the typical view of the cy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f50ddb167e0ce7c18a732338a21b5766
https://doi.org/10.1055/s-0039-1690695
https://doi.org/10.1055/s-0039-1690695
Metal-Free Synthesis of Oxazinones and Their Reductive Ring Opening to Provide Cyclopropyl Carbinols
Autor:
Alexander J. Craig, Bill C. Hawkins
Publikováno v:
Synthesis. 49:1955-1968
General routes for the synthesis of 1,3-oxazin-4-ones are discussed, with particular attention paid to recent developments in the field. The syntheses of amine functionalised cyclopropyl carbinols via a hydride-mediated reduction of various 5-chloroe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90966dc6c87b197ecd2a431290fc6828
https://doi.org/10.1055/s-0036-1588748
https://doi.org/10.1055/s-0036-1588748
Autor:
Lars Stevens-Cullinane, Nigel T. Lucas, Eng Wui Tan, Bill C. Hawkins, Louise van der Salm, Alexander J. Craig
Publikováno v:
Organic Letters. 17:234-237
1,3-Oxazinen-4-ones are medicinally important scaffolds which have traditionally been accessed using a hetero-Diels-Alder approach or more recently using a cobalt-catalyzed three-component cycloaddition. Herein we report a novel strategy to access th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46cc62aef55b5d6ec1799aad0c59e053
https://doi.org/10.1021/ol503350h
https://doi.org/10.1021/ol503350h
Autor:
Eng Wui Tan, Nigel T. Lucas, Alexander J. Craig, Lars Stevens-Cullinane, Louise van der Salm, Bill C. Hawkins
Publikováno v:
ChemInform. 46
Starting from 1-benzoyl or 1-acetylcyclopropane-1-carboxylic acid and a range of imines, the title compounds are synthesized in a high-yielding operationally simple and rapid manner.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::250733dfc9ec29ea77174f4efa1ff57a
https://doi.org/10.1002/chin.201523200
https://doi.org/10.1002/chin.201523200
Autor:
Yoshida, Hiromi, Alexander, J Craig
Publikováno v:
Journal of the Science of Food & Agriculture; 1989, Vol. 48 Issue 2, p245-248, 4p
Autor:
Kummerow, F. A., Alexander, J. Craig, Mackay, Donald A. M., Bates, R. W., Endres, J. G., Showell, John S., Weiss, T. J., Donnelly, T. H., Broaddus, C. D.
Publikováno v:
Journal of the American Oil Chemists' Society; March 1962, Vol. 39 Issue: 3 pa30-a34, 5p