Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Alexander J Winkle"'
Publikováno v:
Cells, Vol 10, Iss 6, p 1516 (2021)
The voltage-gated Na+ channel Nav1.5 is critical for normal cardiac myocyte excitability. Mathematical models have been widely used to study Nav1.5 function and link to a range of cardiac arrhythmias. There is growing appreciation for the importance
Externí odkaz:
https://doaj.org/article/441351a248df4b25a6fb400250e6da18
Autor:
Alexander J. Winkle, Drew M. Nassal, Rebecca Shaheen, Evelyn Thomas, Shivangi Mohta, Daniel Gratz, Seth H. Weinberg, Thomas J. Hund
Publikováno v:
Expert Opin Ther Targets
INTRODUCTION: Cardiac hypertrophy is associated with adverse outcomes across cardiovascular disease states. Despite strides over the last three decades in identifying molecular and cellular mechanisms driving hypertrophy, the link between pathophysio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b52fb0307cb0654a79d0f7290e88520
https://europepmc.org/articles/PMC8885901/
https://europepmc.org/articles/PMC8885901/
Publikováno v:
Cells, Vol 10, Iss 1516, p 1516 (2021)
Cells
Volume 10
Issue 6
Cells
Volume 10
Issue 6
The voltage-gated Na+ channel Nav1.5 is critical for normal cardiac myocyte excitability. Mathematical models have been widely used to study Nav1.5 function and link to a range of cardiac arrhythmias. There is growing appreciation for the importance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8290c841a36c3670c56d55e5dd5967e4
https://www.mdpi.com/2073-4409/10/6/1516
https://www.mdpi.com/2073-4409/10/6/1516
Publikováno v:
Modeling and Simulating Cardiac Electrical Activity ISBN: 9780750320641
Modeling and Simulating Cardiac Electrical Activity
Modeling and Simulating Cardiac Electrical Activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7ea97b63e69ec9172a0383721dff95a
https://doi.org/10.1088/978-0-7503-2064-1ch5
https://doi.org/10.1088/978-0-7503-2064-1ch5
Autor:
Nehal J. Patel, Evelyn Thomas, Thomas J. Hund, Alexander J. Winkle, Sathyadev Unudurthi, Daniel Gratz
Publikováno v:
Circulation Research. 125
Heart failure (HF) is a complex disease characterized by compromised cardiac structure and function. Previous work has identified a link between upregulation of pro-inflammatory cytokines, and HF. There is a critical need to gain better understanding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1850b94a5d0e9927fa0af8cbf43bd5d2
https://doi.org/10.1161/res.125.suppl_1.229
https://doi.org/10.1161/res.125.suppl_1.229
Publikováno v:
PLoS ONE, Vol 19, Iss 8, p e0306128 (2024)
Current strategies to hold surface warming below a certain level, e. g., 1.5 or 2°C, advocate limiting total anthropogenic cumulative carbon emissions to ∼0.9 or ∼1.25 Eg C (1018 grams carbon), respectively. These allowable emission budgets are
Externí odkaz:
https://doaj.org/article/fc689474284b48f7b4026a26980c4185
Publikováno v:
MethodsX, Vol 7, Iss, Pp 100755-(2020)
MethodsX
MethodsX
Graphical abstract
Image processing and quantification is a routine and important task across disciplines in biomedical research. Understanding the effects of disease on the tissue and organ level often requires the use of images, however the pr
Image processing and quantification is a routine and important task across disciplines in biomedical research. Understanding the effects of disease on the tissue and organ level often requires the use of images, however the pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::993ed3d9ae329a0e00f023ca42938f70
https://doi.org/10.1016/j.mex.2019.11.028
https://doi.org/10.1016/j.mex.2019.11.028
Autor:
Reda ElGhawi, Basil Kraft, Christian Reimers, Markus Reichstein, Marco Körner, Pierre Gentine, Alexander J Winkler
Publikováno v:
Environmental Research Letters, Vol 18, Iss 3, p 034039 (2023)
The process of evapotranspiration transfers liquid water from vegetation and soil surfaces to the atmosphere, the so-called latent heat flux ( ${Q_{{\text{LE}}}}$ ), and modulates the Earth’s energy, water, and carbon cycle. Vegetation controls ${Q
Externí odkaz:
https://doaj.org/article/792cd987f1fa44188abc41e155309956