Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Alexander J Sodt"'
Autor:
Eric M Rosenberg, Xiaoying Jian, Olivier Soubias, Rebekah A Jackson, Erin Gladu, Emily Andersen, Lothar Esser, Alexander J Sodt, Di Xia, R Andrew Byrd, Paul A Randazzo
Publikováno v:
PLoS ONE, Vol 19, Iss 4, p e0295103 (2024)
The ADP-ribosylation factors (Arfs) constitute a family of small GTPases within the Ras superfamily, with a distinguishing structural feature of a hypervariable N-terminal extension of the G domain modified with myristate. Arf proteins, including Arf
Externí odkaz:
https://doaj.org/article/c4416d823ace4476a1a0fe1b30cf19ce
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 3, p e1009969 (2022)
Clathrin-coated structures must assemble on cell membranes to internalize receptors, with the clathrin protein only linked to the membrane via adaptor proteins. These structures can grow surprisingly large, containing over 20 clathrin, yet they often
Externí odkaz:
https://doaj.org/article/eca754f7ade44519805ba3b06765e7d4
Publikováno v:
Biophysical Journal. 122:973-983
We monitored the effect on function of the G-protein-coupled receptor (GPCR) rhodopsin from small, stepwise changes in bilayer thickness induced by cholesterol. Over a range of phosphatidylcholine bilayers with hydrophobic thickness from ≈21 Å to
Autor:
William M. Rosencrans, Maria Queralt-Martin, Henry J. Lessen, Motahareh Ghahari Larimi, Megha Rajendran, Tsui-Fen Chou, Radhakrishnan Mahalakshmi, Alexander J. Sodt, Tsyr-Yan Yu, Sergey M. Bezrukov, Tatiana K. Rostovtseva
Publikováno v:
Biophys J
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcb62e57f973ac20ba233fec3cb74d01
https://europepmc.org/articles/PMC7614561/
https://europepmc.org/articles/PMC7614561/
Publikováno v:
Biophysical Journal. 122:228a-229a
Publikováno v:
Biophysical Journal. 122:497a-498a
Autor:
Kazi Rahman, Siddhartha A.K. Datta, Andrew H. Beaven, Abigail A. Jolley, Alexander J. Sodt, Alex A. Compton
The interferon-induced transmembrane (IFITM) proteins broadly inhibit the entry of diverse pathogenic viruses, including Influenza A virus (IAV), Zika virus, HIV-1, and SARS coronaviruses by inhibiting virus-cell membrane fusion. IFITM3 was previousl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1519336cf9a29db8e97e57964320f222
https://doi.org/10.1101/2022.04.21.488780
https://doi.org/10.1101/2022.04.21.488780
Previous experiments have shown that cholesterol strongly prefers concave leaflets (which have negative curvature and are typically thin), but cholesterol also orders and thickens bilayers (promoting liquid-ordered phases with positive curvature). Ou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b697601eeca80679f5f50ea238dbf789
https://doi.org/10.1101/2022.04.15.488512
https://doi.org/10.1101/2022.04.15.488512
Autor:
Edward Lyman, Lutz Maibaum, Frederick A. Heberle, Mitchell Dorrell, Alexander J. Sodt, John Katsaras
Publikováno v:
J Chem Theory Comput
When combined, molecular simulations and small-angle scattering experiments are able to provide molecular-scale resolution of structure. Separately, scattering experiments provide only intermingled pair correlations between atoms, while molecular sim
Publikováno v:
Biophysical journal. 121(17)
Membrane reshaping is an essential biological process. The chemical composition of lipid membranes determines their mechanical properties, and thus the energetics of their shape. Hundreds of distinct lipid species make up native bilayers, and this di