Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Alexander J Ropelewski"'
Autor:
Mariah Kenney, Iaroslavna Vasylieva, Greg Hood, Ivan Cao-Berg, Luke Tuite, Rozita Laghaei, Megan C. Smith, Alan M. Watson, Alexander J. Ropelewski
Publikováno v:
Scientific Data, Vol 11, Iss 1, Pp 1-11 (2024)
Abstract Advancements in microscopy techniques and computing technologies have enabled researchers to digitally reconstruct brains at micron scale. As a result, community efforts like the BRAIN Initiative Cell Census Network (BICCN) have generated th
Externí odkaz:
https://doaj.org/article/35296c1a2825486db21d5e6865fb98e8
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0203218 (2018)
Luciferases, aryl- and fatty-acyl CoA synthetases, and non-ribosomal peptide synthetase proteins belong to the class I adenylate-forming enzyme superfamily. The reaction catalyzed by the adenylate-forming enzymes is categorized by a two-step process
Externí odkaz:
https://doaj.org/article/fcd37408390241d9a0e1e4d33e39e02a
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e13999 (2010)
Phylogenetic study of protein sequences provides unique and valuable insights into the molecular and genetic basis of important medical and epidemiological problems as well as insights about the origins and development of physiological features in pr
Externí odkaz:
https://doaj.org/article/725716e6756e4a79848a6cfbacac013e
Autor:
Alexander J. Ropelewski, Megan A. Rizzo, Jason R. Swedlow, Jan Huisken, Pavel Osten, Neda Khanjani, Kurt Weiss, Vesselina Bakalov, Michelle Engle, Lauren Gridley, Michelle Krzyzanowski, Tom Madden, Deborah Maiese, Meisha Mandal, Justin Waterfield, David Williams, Carol M. Hamilton, Wayne Huggins
Publikováno v:
Scientific Data, Vol 9, Iss 1, Pp 1-8 (2022)
Abstract Recent advances in fluorescence microscopy techniques and tissue clearing, labeling, and staining provide unprecedented opportunities to investigate brain structure and function. These experiments’ images make it possible to catalog brain
Externí odkaz:
https://doaj.org/article/3d9ee52d708f418a9656854eb7dbcc34
Autor:
William J. Greenleaf, Sarah A. Teichmann, Margaret Vella, Ajay Pillai, Aviv Regev, Ananda L. Roy, Kristin E. Burnum-Johnson, Cole Trapnell, Yiing Lin, Marda Jorgensen, Gloria S. Pryhuber, Leslie Gaffney, Ken S. Lau, Kimberly Robasky, Jeffrey M. Spraggins, Chuck McCallum, Stavros Michailidis, Randy Heiland, Orit Rozenblatt-Rosen, Allyson Ricarte, Xin bSun, Kevin J. Otto, Amir Bahmani, Zorina S. Galis, James S. Hagood, Monica Nagendran, Gökcen Eraslan, Robin M. Scibek, Jocelyn Y. Kishi, Jay Mulye, Maria Keays, Griffin M. Weber, Caltech-UW Tmc, Charles Ansong, Nicholas A. Nystrom, Vishal G. Venkataraaman, Vladimir Yu. Kiselev, Ucsd Tmc, Ellen M. Quardokus, Tushar bDesai, Bruce Herr, Engagement Component, James E. Anderson, Shin Lin, Lisel Record, Peter V. Kharchenko, Robert F. dMurphy, Stanford-WashU Tmc, Yu Wang, Jian Ma, Sergio Maffioletti, Sarah Black, Matthew Ruffalo, Salvatore Sechi, John C. Marioni, Ziv Bar-Joseph, Richard M. Caprioli, Stanford Ttd, Garry P. Nolan, Marishka Brown, Elizabeth L. Wilder, Maigan A. Brusko, Peter Chou, Tommaso Biancalani, Christian Martijn Schuerch, Julia Laskin, Richard Conroy, Jonathan C. Silverstein, Paula M. Mabee, Dena Procaccini, Pehr B. Harbury, Michael Snyder, Pothur Srinivas, Jennifer Rood, Dana Jackson, Sanjay Jain, Katy Börner, Visualization HuBMAP Integration, William E. Shirey, Sinem K. Saka, James P. Sluka, Agnes B. Fogo, Isabel Goldaracena, Sushma A. Akoju, Raymond C. Harris, Rahul Satija, Sylvia K. Plevritis, Tim Stuart, Shila Ghazanfar, Peng Yin, Harvard Ttd, Aaron M. Horning, Ed Esplin, Amanda Posgai, Michael J. Clare-Salzler, Raf Van de Plas, Aaron Pawlyk, Guo-Cheng Yuan, Benedict aten, DongHye Ye, Hayan Lee, Eyal Fisher, Jay Shendure, Long Cai, Danielle cGutierrez, Carl Kingsford, Ruben Dries, Sara Ahadi, Paul D. Piehowski, Bernd bBodenmiller, Purdue Ttd, Stephanie A. Nevins, Philip D. Blood, Andrew Butler, W. Christopher Lenhardt, Ying Zhu, Alexander J. Ropelewski, Harry S. Nick, Nathan Heath Patterson, Elizabeth K. Neumann, Anna Hupalowska, Samuel H. Friedman, Clive hWasserfall, Qian Zhu, Mark P. deCaestecker, Leonard E. Cross, Mark A. Atkinson, Paul Macklin, Todd M. Brusko, Eeshit Dhaval Vaishnav, Nils Gehlenborg, Kun Zhang
Publikováno v:
Nature
Transformative technologies are enabling the construction of three-dimensional maps of tissues with unprecedented spatial and molecular resolution. Over the next seven years, the NIH Common Fund Human Biomolecular Atlas Program (HuBMAP) intends to de
Publikováno v:
BioTechniques, Vol 32, Iss 3, Pp 572-591 (2002)
We present an overview of multiple sequence alignments to outline the practical consequences for the choices among different techniques and parameters. We begin with a discussion of the scoring methods for quantifying the quality of a multiple sequen
Externí odkaz:
https://doaj.org/article/c52d9258078648d7bdbd321b673f65f5
Publikováno v:
BioTechniques, Vol 28, Iss 6, Pp 1174-1191 (2000)
We provide a detailed overview of the choices inherent in performing a sequence database search, including the choice of algorithm, substitution matrix and gap model. Each of these choices has implications that can be described as restrictions on the
Externí odkaz:
https://doaj.org/article/4cc47a63e4544b9ab5d50984c1c5143a
Autor:
Alan M. Watson, Alexander J. Ropelewski, Kathy Benninger, Greg Hood, Simon C. Watkins, Arthur W. Wetzel, Marcel P. Bruchez, Derek Simmel, Luke Tuite
Publikováno v:
PEARC
Advances in microscopy technologies and techniques are driving development of an integrated cyberinfrastructure to manage the vast amounts of image data being generated. To address this need, a team of neuroscientists and cyberinfrastructure engineer
Publikováno v:
FEBS Open Bio
Heme oxygenases (HO) catalyze the breakdown of heme, aiding the recycling of its components. Several other enzymes have homologous tertiary structures to HOs, while sharing little sequence homology. These homologues include thiaminases, the hydroxyla
Autor:
Parthasarathy Ranganathan, Koen Vercruysse, Theodore W. Thannhauser, Suping Zhou, Terrance Johnson, Hui Li, Nsoki Phambu, Alexander J. Ropelewski, Ouyang Lizhi
Publikováno v:
International Journal of Polymer Science, Vol 2017 (2017)
In previous work, we reported on the isolation and genome sequence analysis ofBacillus cereusstrain tsu1 NCBI accession number JPYN00000000. The 36 scaffolds in the assembled tsu1 genome were all aligned withB. cereusB4264 genome with variations. Gen