Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Alexander J Prokopienko"'
Autor:
Amy Barton Pai, Heena Patel, Alexander J Prokopienko, Hiba Alsaffar, Nancy Gertzberg, Paul Neumann, Anjoli Punjabi, Arnold Johnson
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e49209 (2012)
Tunneled central venous catheters (TCVCs) are used for dialysis access in 82% of new hemodialysis patients and are rapidly colonized with Gram-positive organism (e.g. Staphylococcus aureus) biofilm, a source of recurrent infections and chronic inflam
Externí odkaz:
https://doaj.org/article/57ecddb1666f48febce17b481dc8e31e
Autor:
Marissa Renardy, Alexander J. Prokopienko, Joseph R. Maxwell, Deborah A. Flusberg, Sahak Makaryan, Jangir Selimkhanov, Majid Vakilynejad, Kalyanasundaram Subramanian, Lucia Wille
Publikováno v:
Clinical Pharmacology & Therapeutics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fcdeee12b4c2c6d7d0a9d0999e086237
https://doi.org/10.1002/cpt.2952
https://doi.org/10.1002/cpt.2952
Autor:
Michel Chonchol, Anna Jovanovich, Charles E. Robertson, Thomas D. Nolin, Bryan Kestenbaum, Andrew N. Hoofnagle, Daniel N. Frank, Alexander J. Prokopienko, Jason R. Stubbs, Shiqin Zhang, Cassandra Johnson, Raymond E. West, Diana Ir, Cassandra Kimber, Makoto Miyazaki, Jonathan D. Mahnken, Alan S.L. Yu
Publikováno v:
Kidney360
Background Recent evidence suggests the systemic accumulation of by-products of gut microbes contributes to cardiovascular morbidity in patients with CKD. Limiting the generation of toxic bacterial by-products by manipulating the intestinal microbiot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baf37c33a96a394f2cd9cbfd1a6fc6e6
https://doi.org/10.34067/kid.0003942020
https://doi.org/10.34067/kid.0003942020
Autor:
Thomas D. Nolin, Jonathan D. Mahnken, Margaret R. Stedman, Jin Long, Jason R. Stubbs, Yoko Franchetti, Sai Liu, Glenn M. Chertow, Alexander J. Prokopienko, Raymond E. West
Publikováno v:
Clinical Journal of the American Society of Nephrology. 14:261-267
Background and objectives Trimethylamine N-oxide (TMAO), a compound derived from byproducts of intestinal bacteria, has been shown to accelerate atherosclerosis in rodents. To date, there are conflicting data regarding the association of serum TMAO w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22590dfff37f44ea12ffb6c7b782ef47
https://doi.org/10.2215/cjn.06190518
https://doi.org/10.2215/cjn.06190518
Publikováno v:
International Journal of Nephrology, Vol 2013 (2013)
Patients on hemodialysis (HD) have a high burden of chronic inflammation induced associated with multiple comorbidities including poor nutritional status. Endotoxin (ET) is a Gram-negative bacterial cell wall component and a potent stimulus for innat
Externí odkaz:
https://doaj.org/article/0a3ec01d6d1d43a797f2bc04918fe785
Autor:
Thomas D. Nolin, Saran Kupul, Michail S. Lionakis, Jigar V. Desai, Chetan V. Jawale, Sarah L. Gaffen, Partha S. Biswas, Bianca M. Coleman, De-Dong Li, Filitsa H. Bender, Li Lin, Greg M. Delgoffe, Alexander J. Prokopienko, Kritika Ramani, Rohan S. Oberoi
Publikováno v:
Science Translational Medicine. 12
Disseminated candidiasis caused by the fungus Candida albicans is a major clinical problem in individuals with kidney disease and accompanying uremia; disseminated candidiasis fatality is twice as common in patients with uremia as those with normal k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::553d8cc354e57d7b1bde61dec2e17b54
https://doi.org/10.1126/scitranslmed.aay5691
https://doi.org/10.1126/scitranslmed.aay5691
Autor:
Thomas D. Nolin, Cassandra Johnson, Jason R. Stubbs, Raymond E. West, Alexander J. Prokopienko
Publikováno v:
Drug Metabolism and Disposition. 46:1304-1309
Circulating trimethylamine N-oxide (TMAO) predicts poor cardiovascular outcomes in patients with chronic kidney disease (CKD). Accumulation of serum TMAO has been observed in CKD patients; however, the mechanisms contributing to this finding have bee
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::45193d9a833389c3e6ff25f793e7a47d
https://doi.org/10.1124/dmd.118.081646
https://doi.org/10.1124/dmd.118.081646
Autor:
Thomas D. Nolin, Jason R. Stubbs, Alexander J. Prokopienko, Raymond E. West, François A. Leblond, Daniel P. Schrum, Vincent Pichette
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-10 (2019)
Cardiovascular disease (CVD) remains the leading cause of death in chronic kidney disease (CKD) patients despite treatment of traditional risk factors, suggesting that non-traditional CVD risk factors are involved. Trimethylamine-N-oxide (TMAO) corre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8b8cd36018446f59ddf811164f25e83
http://europepmc.org/articles/PMC6828678
http://europepmc.org/articles/PMC6828678
Publikováno v:
J Pharm Biomed Anal
Gut-derived uremic toxins contribute to the uremic syndrome and are gaining attention as potentially modifiable cardiovascular disease risk factors in patients with underlying chronic kidney disease. A simple, rapid, robust, accurate and precise ultr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ace44377c189a66a2cb050f0cefbb79
https://europepmc.org/articles/PMC6677161/
https://europepmc.org/articles/PMC6677161/
Autor:
Sarah L. Gaffen, Bianca M. Coleman, Chetan V. Jawale, Thomas D. Nolin, Michail S. Lionakis, Greg M. Delgoffe, Partha S. Biswas, Saran Kupul, Rohan S. Oberoi, Alexander J. Prokopienko, Jigar V. Desai, Kritika Ramani
Publikováno v:
SSRN Electronic Journal.
Disseminated candidiasis (DC) caused by the fungus Candida albicans is a major clinical problem in individuals with kidney disease and accompanying uremia. DC fatality is twice as common in patients with uremia as those without renal impairments. Man
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9b212cd4fc0a5bd5717781bcf0072bf2
https://doi.org/10.2139/ssrn.3403336
https://doi.org/10.2139/ssrn.3403336