Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Alexander J Diaz de Arce"'
Autor:
William L Noderer, Ross J Flockhart, Aparna Bhaduri, Alexander J Diaz de Arce, Jiajing Zhang, Paul A Khavari, Clifford L Wang
Publikováno v:
Molecular Systems Biology, Vol 10, Iss 8, Pp 1-14 (2014)
Abstract An approach combining fluorescence‐activated cell sorting and high‐throughput DNA sequencing (FACS‐seq) was employed to determine the efficiency of start codon recognition for all possible translation initiation sites (TIS) utilizing A
Externí odkaz:
https://doaj.org/article/625d5f659358470db2db9b4ec490a83b
Publikováno v:
Nucleic Acids Research
The initiation of mRNA translation from start codons other than AUG was previously believed to be rare and of relatively low impact. More recently, evidence has suggested that as much as half of all translation initiation utilizes non-AUG start codon
Publikováno v:
Bioengineered. 5:186-192
We have employed upstream open reading frames (uORFs) to systematically tune the translation levels of recombinant proteins. We present the design principles that guided the development of this technology and provide information that may help others
Autor:
Ross J. Flockhart, Jiajing Zhang, Aparna Bhaduri, William L Noderer, Alexander J Diaz de Arce, Clifford L. Wang, Paul A. Khavari
Publikováno v:
Molecular Systems Biology
An approach combining fluorescence-activated cell sorting and high-throughput DNA sequencing (FACS-seq) was employed to determine the efficiency of start codon recognition for all possible translation initiation sites (TIS) utilizing AUG start codons