Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Alexander J Davenport"'
Autor:
Katharine J Drummond, Jordan R Hansford, Misty R Jenkins, Lisa M Ebert, Leesa Lertsumitkul, Melinda Iliopoulos, Stacie S Wang, Sarah J McArthur, Alexander J Davenport, Raelene Endersby, Ryan Cross
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 8 (2024)
Background High-grade gliomas including glioblastoma (GBM) and diffuse midline gliomas (DMG) represent the most lethal and aggressive brain cancers where current treatment modalities offer limited efficacy. Chimeric antigen receptor (CAR) T cell ther
Externí odkaz:
https://doaj.org/article/ddf80a4505ed43e2bee311a611917b42
Autor:
Paul J. Neeson, Phillip K. Darcy, Michael H. Kershaw, Joseph A. Trapani, David S. Ritchie, H. Miles Prince, Carmen S. Yong, Ryan S. Cross, Misty R. Jenkins, Alexander J. Davenport
Adoptive therapy with chimeric antigen receptor (CAR) T cells shows great promise clinically. However, there are important aspects of CAR-T-cell biology that have not been explored, particularly with respect to the kinetics of activation, immune syna
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae2664785a285bb49ff5f9a4ce793a3b
https://doi.org/10.1158/2326-6066.c.6548806.v1
https://doi.org/10.1158/2326-6066.c.6548806.v1
Autor:
Phillip K. Darcy, Nicole M. Haynes, Michael H. Kershaw, Sherene Loi, Joseph A. Trapani, Clare Y. Slaney, Sherly Mardiana, Liza B. John, Nicole Milenkovski, Kevin Sek, Junyun Lai, Imran G. House, Emma V. Petley, Alexander J. Davenport, Lauren Giuffrida, Melissa A. Henderson, Paul A. Beavis
Immunotherapy is widely accepted as a powerful new treatment modality for the treatment of cancer. The most successful form of immunotherapy to date has been the blockade of the immune checkpoints PD-1 and CTLA-4. Combining inhibitors of both PD-1 an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06613cc65779fd52877cccabc16a12c3
https://doi.org/10.1158/2326-6066.c.6549253.v1
https://doi.org/10.1158/2326-6066.c.6549253.v1
Autor:
Paul J. Neeson, Phillip K. Darcy, Michael H. Kershaw, Joseph A. Trapani, David S. Ritchie, H. Miles Prince, Carmen S. Yong, Ryan S. Cross, Misty R. Jenkins, Alexander J. Davenport
Movie 5. Serial killing of tumor targets by CAR.OT-I effector cells following engagement through the CAR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02736380182beccb475773a65593a9df
https://doi.org/10.1158/2326-6066.22538515
https://doi.org/10.1158/2326-6066.22538515
Autor:
Paul J. Neeson, Phillip K. Darcy, Michael H. Kershaw, Joseph A. Trapani, David S. Ritchie, H. Miles Prince, Carmen S. Yong, Ryan S. Cross, Misty R. Jenkins, Alexander J. Davenport
Movie 2. CAR.OT-I cells co-cultured with MC57-OVA257 cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8722c039ce594ac04ed58f03f4a15a52
https://doi.org/10.1158/2326-6066.22538524.v1
https://doi.org/10.1158/2326-6066.22538524.v1
Autor:
Phillip K. Darcy, Nicole M. Haynes, Michael H. Kershaw, Sherene Loi, Joseph A. Trapani, Clare Y. Slaney, Sherly Mardiana, Liza B. John, Nicole Milenkovski, Kevin Sek, Junyun Lai, Imran G. House, Emma V. Petley, Alexander J. Davenport, Lauren Giuffrida, Melissa A. Henderson, Paul A. Beavis
Supplementary Figure 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fa70920f2ea2ffa82c316b0ad43d943
https://doi.org/10.1158/2326-6066.22540024
https://doi.org/10.1158/2326-6066.22540024
Autor:
Paul J. Neeson, Phillip K. Darcy, Michael H. Kershaw, Joseph A. Trapani, David S. Ritchie, H. Miles Prince, Carmen S. Yong, Ryan S. Cross, Misty R. Jenkins, Alexander J. Davenport
Movie 4. Serial killing of tumor targets by CAR.OT-I effector cells following engagement through the TCR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e3f8132136d64cc8d9bc2dff4656536
https://doi.org/10.1158/2326-6066.22538518.v1
https://doi.org/10.1158/2326-6066.22538518.v1
Autor:
Paul J. Neeson, Phillip K. Darcy, Michael H. Kershaw, Joseph A. Trapani, David S. Ritchie, H. Miles Prince, Carmen S. Yong, Ryan S. Cross, Misty R. Jenkins, Alexander J. Davenport
Supplementary Figure 2. OVA257 peptide dose does not affect effector cell maturation status.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae5c2bdce5a2f63f4d7eaf5ea5be3a23
https://doi.org/10.1158/2326-6066.22538533
https://doi.org/10.1158/2326-6066.22538533
Autor:
Paul J. Neeson, Phillip K. Darcy, Michael H. Kershaw, Joseph A. Trapani, David S. Ritchie, H. Miles Prince, Carmen S. Yong, Ryan S. Cross, Misty R. Jenkins, Alexander J. Davenport
Movie 3. CAR.OT-I cells co-cultured with MC57-HER2 cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f23e7e038a0d767b33a771ceb53dd92
https://doi.org/10.1158/2326-6066.22538521.v1
https://doi.org/10.1158/2326-6066.22538521.v1
Autor:
Paul J. Neeson, Phillip K. Darcy, Michael H. Kershaw, Joseph A. Trapani, David S. Ritchie, H. Miles Prince, Carmen S. Yong, Ryan S. Cross, Misty R. Jenkins, Alexander J. Davenport
Supplementary Figure 1. TCR activated OT-I and CAR. OT-I cells display similar expression levels of cytotoxic granules.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e971e7aae1cb642b53c88f88aebe2d9
https://doi.org/10.1158/2326-6066.22538536
https://doi.org/10.1158/2326-6066.22538536