Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Alexander Jürets"'
Autor:
Zrinka Didara, Florian Reithofer, Karina Zöttl, Alexander Jürets, Izabella Kiss, Angela Witte, Reinhard Klein
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 32, Iss , Pp 48-60 (2023)
DNA-targeting CRISPR-Cas systems are able to cleave dsDNA in mammalian cells. Accordingly, they have been employed to target the genomes of dsDNA viruses, mostly when present in cells in a non-replicative state with low copy numbers. However, the she
Externí odkaz:
https://doaj.org/article/9c53429b6e314a659dd5f1d4d43dbffc
Autor:
Bettina Wanko, Matteo Tardelli, Alexander Jürets, Angelika Neuhofer, Gerhard Prager, John Morser, Lawrence L Leung, Günther Staffler, Maximilian Zeyda, Thomas M Stulnig
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0214938 (2019)
T cells are crucial players in obesity-mediated adipose tissue inflammation. We hypothesized that osteopontin (OPN), an inflammatory protein with enhanced activity when proteolytically cleaved, affects the number of viable T cells in adipose tissue a
Externí odkaz:
https://doaj.org/article/ab0a37a4536d4796b1998b8bb7a7db63
Autor:
Alexander Jürets, Marie Le Bras, Günther Staffler, Gesine Stein, Lukas Leitner, Angelika Neuhofer, Matteo Tardelli, Edvin Turkof, Maximilian Zeyda, Thomas M Stulnig
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0148333 (2016)
Osteopontin (OPN), a secreted protein involved in inflammatory processes and cancer, induces cell adhesion, migration, and activation of inflammatory pathways in various cell types. Cells bind OPN via integrins at a canonical RGD region in the full l
Externí odkaz:
https://doaj.org/article/df861ee86c3841409a854f48e64c1ab4
Autor:
Matthias Egger, Alexander Jürets, Michael Wallner, Peter Briza, Silke Ruzek, Stefan Hainzl, Ulrike Pichler, Claudia Kitzmüller, Barbara Bohle, Christian G Huber, Fátima Ferreira
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e17278 (2011)
The growing number of novel candidate molecules for the treatment of allergic diseases imposed a dramatic increase in the demand for animal experiments to select immunogenic vaccines, a pre-requisite for efficacy. Because no in vitro methods to predi
Externí odkaz:
https://doaj.org/article/a0cdbc490b274adaa2c5bcc64cd81fe2
Autor:
Viktor Grablowitz, Gerhard Prager, Alexander Jürets, Thomas M. Stulnig, Melina Amor, Maximilian Zeyda, Magdalena Keindl, Felix B. Langer, Veronica Moreno-Viedma, Bianca K. Itariu
Publikováno v:
Experimental and Clinical Endocrinology & Diabetes. 127:550-556
Obesity and type 2 diabetes mellitus have reached an epidemic level, thus novel treatment concepts need to be identified. Myostatin, a myokine known for restraining skeletal muscle growth, has been associated with the development of insulin resistanc
Autor:
Lukas Leitner, Thomas M. Stulnig, Alexander Jürets, Maike Keck, Maximilian Zeyda, Gerhard Prager, Felix B. Langer, Bianca K. Itariu, Viktor Grablowitz
Publikováno v:
Breast Cancer Research and Treatment. 154:63-69
Breast and endometrial cancer are often estrogen dependent, and their incidence and mortality are increased by obesity in postmenopausal women. Osteopontin (OPN) is a cytokine strongly upregulated in adipose tissue (AT) in obesity. OPN function is po
Autor:
Bettina Wanko, Matteo Tardelli, Alexander Jürets, Angelika Neuhofer, Gerhard Prager, John Morser, Lawrence L Leung, Günther Staffler, Maximilian Zeyda, Thomas M Stulnig
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 4, p e0214938 (2019)
PLoS ONE, Vol 14, Iss 4, p e0214938 (2019)
T cells are crucial players in obesity-mediated adipose tissue inflammation. We hypothesized that osteopontin (OPN), an inflammatory protein with enhanced activity when proteolytically cleaved, affects the number of viable T cells in adipose tissue a
Autor:
Maike Keck, Lukas Leitner, Maximilian Zeyda, Günther Staffler, Thomas M. Stulnig, Alexander Jürets, Bianca K. Itariu, Viktor Grablowitz, Gerhard Prager, Karina Schuch, Oskar C. Aszmann
Publikováno v:
Obesity. 23:779-785
Objective Osteopontin (OPN) is upregulated in adipose tissue (AT) in obesity and contributes to subclinical inflammation, adipocyte dysfunction, and insulin resistance. OPN effects can be increased by cleavage by matrix metalloproteinases (MMP). This
Autor:
Egger, Matthias1 matthias.egger@sbg.ac.at, Alexander Jürets2, Wallner, Michael1, Briza, Peter2, Ruzek, Silke3, Hainzl, Stefan4, Pichler, Ulrike2, ller, Claudia Kitzmü5, Bohle, Barbara5, Huber, Christian G.3, Ferreira, Fátima1
Publikováno v:
PLoS ONE. 2011, Vol. 6 Issue 2, p1-8. 8p.
Autor:
Günther Staffler, Alexander Jürets, Lukas Leitner, Marie Le Bras, Edvin Turkof, Thomas M. Stulnig, Matteo Tardelli, Angelika Neuhofer, Gesine Stein, Maximilian Zeyda
Publikováno v:
PLoS ONE
PLoS ONE, Vol 11, Iss 2, p e0148333 (2016)
PLoS ONE, Vol 11, Iss 2, p e0148333 (2016)
Osteopontin (OPN), a secreted protein involved in inflammatory processes and cancer, induces cell adhesion, migration, and activation of inflammatory pathways in various cell types. Cells bind OPN via integrins at a canonical RGD region in the full l