Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Alexander J, Tarashansky"'
Autor:
Pengyang Li, Dania Nanes Sarfati, Yuan Xue, Xi Yu, Alexander J. Tarashansky, Stephen R. Quake, Bo Wang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)
Our understanding of how the germline of the parasitic flatworm Schistosoma mansoni develops is limited. Here, the authors use single cell RNAseq and functional genomic analysis of juvenile worms to identify a regulatory program that mediates the fat
Externí odkaz:
https://doaj.org/article/4176f353afde4a5ab745c9d925350888
Autor:
Alexander J Tarashansky, Jacob M Musser, Margarita Khariton, Pengyang Li, Detlev Arendt, Stephen R Quake, Bo Wang
Publikováno v:
eLife, Vol 10 (2021)
Comparing single-cell transcriptomic atlases from diverse organisms can elucidate the origins of cellular diversity and assist the annotation of new cell atlases. Yet, comparison between distant relatives is hindered by complex gene histories and div
Externí odkaz:
https://doaj.org/article/e61b8c6e924b4228a38a43ea366b4ea4
Publikováno v:
eLife, Vol 8 (2019)
Single-cell RNA sequencing has spurred the development of computational methods that enable researchers to classify cell types, delineate developmental trajectories, and measure molecular responses to external perturbations. Many of these technologie
Externí odkaz:
https://doaj.org/article/740adc2d92264225986e6b952593d705
Autor:
Jun Xu, Yifang Liu, Hongjie Li, Alexander J. Tarashansky, Colin H. Kalicki, Ruei-Jiun Hung, Yanhui Hu, Aram Comjean, Sai Saroja Kolluru, Bo Wang, Stephen R. Quake, Liqun Luo, Andrew P. McMahon, Julian A. T. Dow, Norbert Perrimon
Publikováno v:
Proceedings of the National Academy of Sciences. 119
Recent advances in single-cell sequencing provide a unique opportunity to gain novel insights into the diversity, lineage, and functions of cell types constituting a tissue/organ. Here, we performed a single-nucleus study of the adult Drosophila rena
Autor:
Robert C, Jones, Jim, Karkanias, Mark A, Krasnow, Angela Oliveira, Pisco, Stephen R, Quake, Julia, Salzman, Nir, Yosef, Bryan, Bulthaup, Phillip, Brown, William, Harper, Marisa, Hemenez, Ravikumar, Ponnusamy, Ahmad, Salehi, Bhavani A, Sanagavarapu, Eileen, Spallino, Ksenia A, Aaron, Waldo, Concepcion, James M, Gardner, Burnett, Kelly, Nikole, Neidlinger, Zifa, Wang, Sheela, Crasta, Saroja, Kolluru, Maurizio, Morri, Serena Y, Tan, Kyle J, Travaglini, Chenling, Xu, Marcela, Alcántara-Hernández, Nicole, Almanzar, Jane, Antony, Benjamin, Beyersdorf, Deviana, Burhan, Kruti, Calcuttawala, Matthew M, Carter, Charles K F, Chan, Charles A, Chang, Stephen, Chang, Alex, Colville, Rebecca N, Culver, Ivana, Cvijović, Gaetano, D'Amato, Camille, Ezran, Francisco X, Galdos, Astrid, Gillich, William R, Goodyer, Yan, Hang, Alyssa, Hayashi, Sahar, Houshdaran, Xianxi, Huang, Juan C, Irwin, SoRi, Jang, Julia Vallve, Juanico, Aaron M, Kershner, Soochi, Kim, Bernhard, Kiss, William, Kong, Maya E, Kumar, Angera H, Kuo, Rebecca, Leylek, Baoxiang, Li, Gabriel B, Loeb, Wan-Jin, Lu, Sruthi, Mantri, Maxim, Markovic, Patrick L, McAlpine, Antoine, de Morree, Karim, Mrouj, Shravani, Mukherjee, Tyler, Muser, Patrick, Neuhöfer, Thi D, Nguyen, Kimberly, Perez, Ragini, Phansalkar, Nazan, Puluca, Zhen, Qi, Poorvi, Rao, Hayley, Raquer-McKay, Nicholas, Schaum, Bronwyn, Scott, Bobak, Seddighzadeh, Joe, Segal, Sushmita, Sen, Shaheen, Sikandar, Sean P, Spencer, Lea C, Steffes, Varun R, Subramaniam, Aditi, Swarup, Michael, Swift, Will, Van Treuren, Emily, Trimm, Stefan, Veizades, Sivakamasundari, Vijayakumar, Kim Chi, Vo, Sevahn K, Vorperian, Wanxin, Wang, Hannah N W, Weinstein, Juliane, Winkler, Timothy T H, Wu, Jamie, Xie, Andrea R, Yung, Yue, Zhang, Angela M, Detweiler, Honey, Mekonen, Norma F, Neff, Rene V, Sit, Michelle, Tan, Jia, Yan, Gregory R, Bean, Vivek, Charu, Erna, Forgó, Brock A, Martin, Michael G, Ozawa, Oscar, Silva, Angus, Toland, Venkata N P, Vemuri, Shaked, Afik, Kyle, Awayan, Olga Borisovna, Botvinnik, Ashley, Byrne, Michelle, Chen, Roozbeh, Dehghannasiri, Adam, Gayoso, Alejandro A, Granados, Qiqing, Li, Gita, Mahmoudabadi, Aaron, McGeever, Julia Eve, Olivieri, Madeline, Park, Neha, Ravikumar, Geoff, Stanley, Weilun, Tan, Alexander J, Tarashansky, Rohan, Vanheusden, Peter, Wang, Sheng, Wang, Galen, Xing, Rebecca, Culver, Les, Dethlefsen, Po-Yi, Ho, Shixuan, Liu, Jonathan S, Maltzman, Ross J, Metzger, Koki, Sasagawa, Rahul, Sinha, Hanbing, Song, Bruce, Wang, Steven E, Artandi, Philip A, Beachy, Michael F, Clarke, Linda C, Giudice, Franklin W, Huang, Kerwyn Casey, Huang, Juliana, Idoyaga, Seung K, Kim, Mark, Krasnow, Christin S, Kuo, Patricia, Nguyen, Thomas A, Rando, Kristy, Red-Horse, Jeremy, Reiter, David A, Relman, Justin L, Sonnenburg, Albert, Wu, Sean M, Wu, Tony, Wyss-Coray
Publikováno v:
Science
Tabula Sapiens Consortium* 2022, ' The Tabula Sapiens : A multiple-organ, single-cell transcriptomic atlas of humans ', Science (New York, N.Y.), vol. 376, no. 6594, pp. eabl4896 . https://doi.org/10.1126/science.abl4896
Tabula Sapiens Consortium* 2022, ' The Tabula Sapiens : A multiple-organ, single-cell transcriptomic atlas of humans ', Science (New York, N.Y.), vol. 376, no. 6594, pp. eabl4896 . https://doi.org/10.1126/science.abl4896
INTRODUCTION: Although the genome is often called the blueprint of an organism, it is perhaps more accurate to describe it as a parts list composed of the various genes that may or may not be used in the different cell types of a multicellular organi
Autor:
Jun Xu, Norbert Perrimon, Julian A. T. Dow, Bo Wang, Sai Saroja Kolluru, Alexander J. Tarashansky, Liqun Luo, Colin H. Kalicki, Stephen R. Quake, Ruei-Jiun Hung, Aram Comjean, Yanhui Hu, Yifang Liu, Andrew P. McMahon, Hongjie Li
SUMMARYLike humans, insects rely on precise regulation of their internal environments to survive. The insect renal system consists of Malpighian tubules and nephrocytes that share similarities to the mammalian kidney. Studies of the Drosophila Malpig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d2ab3712906225704f4108d27f98513
https://doi.org/10.1101/2021.09.03.458871
https://doi.org/10.1101/2021.09.03.458871
Publikováno v:
Trends Parasitol
Schistosomes cause one of the most devastating neglected tropical diseases, schistosomiasis. Their transmission is accomplished through a complex life cycle with two obligate hosts and requires multiple radically different body plans specialized for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6058593fc2c46213d44299774202469
https://europepmc.org/articles/PMC8364473/
https://europepmc.org/articles/PMC8364473/
Autor:
Alexandra, Tsitsiklis, Beth Shoshana, Zha, Ashley, Byrne, Catherine, DeVoe, Elze, Rackaityte, Sophia, Levan, Sara, Sunshine, Eran, Mick, Rajani, Ghale, Christina, Love, Alexander J, Tarashansky, Angela, Pisco, Jack, Albright, Alejandra, Jauregui, Aartik, Sarma, Norma, Neff, Paula Hayakawa, Serpa, Thomas J, Deiss, Amy, Kistler, Sidney, Carrillo, K Mark, Ansel, Aleksandra, Leligdowicz, Stephanie, Christenson, Angela, Detweiler, Norman G, Jones, Bing, Wu, Spyros, Darmanis, Susan V, Lynch, Joseph L, DeRisi, Michael A, Matthay, Carolyn M, Hendrickson, Kirsten N, Kangelaris, Matthew F, Krummel, Prescott G, Woodruff, David J, Erle, Oren, Rosenberg, Carolyn S, Calfee, Charles R, Langelier
Publikováno v:
medRxiv
Secondary bacterial infections, including ventilator-associated pneumonia (VAP), lead to worse clinical outcomes and increased mortality following viral respiratory infections. Critically ill patients with coronavirus disease 2019 (COVID-19) face an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::733cf4f353fc54e32ab6557b09d82869
https://doi.org/10.1101/2021.03.23.21253487
https://doi.org/10.1101/2021.03.23.21253487
Autor:
Margarita Khariton, Detlev Arendt, Pengyang Li, Jacob M. Musser, Alexander J. Tarashansky, Stephen R. Quake, Bo Wang
Publikováno v:
eLife
bioRxiv
eLife, Vol 10 (2021)
bioRxiv
eLife, Vol 10 (2021)
Comparing single-cell transcriptomic atlases from diverse organisms can elucidate the origins of cellular diversity and assist the annotation of new cell atlases. Yet, comparison between distant relatives is hindered by complex gene histories and div