Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Alexander J, Leeder"'
Autor:
Christian Bamann, Richard C. D. Brown, Alexander J. Leeder, Lynda J. Brown, Johanna Becker-Baldus, Clemens Glaubitz
Publikováno v:
Angewandte Chemie (International Ed. in English)
Channelrhodopsin‐2 (ChR2) is a light‐gated cation channel and was used to lay the foundations of optogenetics. Its dark state X‐ray structure has been determined in 2017 for the wild‐type, which is the prototype for all other ChR variants. Ho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45bf89a7a517045b5b3f6391dc058ed9
http://europepmc.org/articles/PMC8362212
http://europepmc.org/articles/PMC8362212
Autor:
Christian Bamann, Johanna Becker-Baldus, Josef Wachtveitl, Peter Eberhardt, Clara Nassrin Kriebel, Lynda J. Brown, Richard C. D. Brown, Clemens Glaubitz, Alexander J. Leeder, Jagdeep Kaur, Orawan Jakdetchai, Ingrid Weber
Publikováno v:
Journal of Structural Biology. 206:55-65
Krokinobacter eikastus rhodopsin 2 (KR2) is a pentameric, light-driven ion pump, which selectively transports sodium or protons. The mechanism of ion selectivity and transfer is unknown. By using conventional as well as dynamic nuclear polarization (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1e87f9abbf4c00d1ed08f0e3de414a5
https://doi.org/10.1016/j.jsb.2018.06.001
https://doi.org/10.1016/j.jsb.2018.06.001
Autor:
Victoria Aladin, Clemens Glaubitz, Jiafei Mao, Xiao He, Alexander J. Leeder, Björn Corzilius, Xinsheng Jin, Lynda J. Brown, Richard C. D. Brown
Although the rapid development of sensitivity-enhanced solid-state NMR (ssNMR) spectroscopy based on dynamic nuclear polarization (DNP) has enabled a broad range of novel applications in material and life sciences, further methodological improvements
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b3c22816db447b188c3d8ade9b65764
https://eprints.soton.ac.uk/436555/
https://eprints.soton.ac.uk/436555/
Autor:
Clemens Glaubitz, Tobias Fischer, Carl Elias Eckert, Lynda J. Brown, Richard C. D. Brown, Michaela Mehler, Johanna Becker-Baldus, Jagdeep Kaur, Nina Kubatova, Josef Wachtveitl, Alexander J. Leeder
Proteorhodopsin (PR) is the most abundant retinal protein on earth and functions as a light-driven proton pump. Despite of extensive efforts, structural data for PR photointermediate states have not been obtained. Based on DNP-enhanced solid-state NM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4577ccd1b5442516178f32afa3bc31ed
https://eprints.soton.ac.uk/415161/
https://eprints.soton.ac.uk/415161/
Autor:
Alexander J. Leeder, Richard C. D. Brown, Clemens Glaubitz, Lynda J. Brown, Johanna Becker-Baldus, Michaela Mehler
Publikováno v:
Journal of labelled compoundsradiopharmaceuticals. 61(13)
Three all-trans retinals containing multiple 13C labels have been synthesized to enable dynamic nuclear polarization enhanced solid-state magic angle spinning NMR studies of novel microbial retinylidene membrane proteins including proteorhodpsin and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3eb7735fc337841c7d097723a626c172
https://pubmed.ncbi.nlm.nih.gov/29080288
https://pubmed.ncbi.nlm.nih.gov/29080288
Publikováno v:
Organic letters. 18(23)
A total synthesis of the (±)-vibralactone has been achieved in 11 steps and 16% overall yield from malonic acid. Key steps include a highly diastereoselective allylation of an α-formyl ester containing an all carbon α-quaternary center, a Pd-catal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d09da7e1062fdc3a9a5a8094cbda5b58
https://pubmed.ncbi.nlm.nih.gov/27797210
https://pubmed.ncbi.nlm.nih.gov/27797210