Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Alexander I. Son"'
Autor:
Seiji Ishii, Masaaki Torii, Alexander I. Son, Meenu Rajendraprasad, Yury M. Morozov, Yuka Imamura Kawasawa, Anna C. Salzberg, Mitsuaki Fujimoto, Kristen Brennand, Akira Nakai, Valerie Mezger, Fred H. Gage, Pasko Rakic, Kazue Hashimoto-Torii
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Prenatal exposure to environmental stressors is known to impair cortical development. Here the authors show that upon exposure to stressors, the activation of Hsf1-Hsp signalling is highly variable among cells in the embryonic cortex of mice, and eit
Externí odkaz:
https://doaj.org/article/799a96f9df824be3a9794751c745b994
Publikováno v:
Genes, Vol 4, Iss 3, Pp 334-357 (2013)
The Eph family of receptor tyrosine kinases (RTKs) has been implicated in the regulation of many aspects of mammalian development. Recent analyses have revealed that the EphA2 receptor is a key modulator for a wide variety of cellular functions. This
Externí odkaz:
https://doaj.org/article/6cd141db3b45472f8e7b15152b95967b
Autor:
Xiaoqin Fu, Lu Rao, Peijun Li, Xinglei Liu, Qi Wang, Alexander I Son, Arne Gennerich, Judy Shih-Hwa Liu
Publikováno v:
eLife, Vol 11 (2022)
Mutations in the microtubule (MT)-binding protein doublecortin (DCX) or in the MT-based molecular motor dynein result in lissencephaly. However, a functional link between DCX and dynein has not been defined. Here, we demonstrate that DCX negatively r
Externí odkaz:
https://doaj.org/article/64373830ab2f4cd1846a64ce86b5d746
Autor:
Kazue Hashimoto-Torii, Yuka Imamura Kawasawa, Fred H. Gage, Pasko Rakic, Mitsuaki Fujimoto, Masaaki Torii, Akira Nakai, Meenu Rajendraprasad, Alexander I. Son, Seiji Ishii, Kristen J. Brennand, Valérie Mezger, Anna C. Salzberg, Yury M. Morozov
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
Nature Communications
Nature Communications, Nature Publishing Group, 2017, 8 (1), pp.15157. ⟨10.1038/ncomms15157⟩
Nature Communications
Nature Communications, Nature Publishing Group, 2017, 8 (1), pp.15157. ⟨10.1038/ncomms15157⟩
Repetitive prenatal exposure to identical or similar doses of harmful agents results in highly variable and unpredictable negative effects on fetal brain development ranging in severity from high to little or none. However, the molecular and cellular
Publikováno v:
Experimental Eye Research. 145:130-139
Ephrin-A5, a ligand of the Eph family of receptor tyrosine kinases, plays a key role in lens fiber cell packing and cell-cell adhesion, with approximately 87% of ephrin-A5(-/-) mice develop nuclear cataracts. Here, we investigated the extensive forma
Publikováno v:
Journal of Comparative Neurology. 524:2080-2092
Deciphering the molecular basis for guiding specific aspects of neocortical development remains a challenge because of the complexity of histogenic events and the vast array of protein interactions mediating these events. The Eph family of receptor t
Autor:
Yuka Imamura Kawasawa, Shahid Mohammad, Alexander I. Son, Hiroki Morizono, Aiesha Basha, Anna C. Salzberg, Masaaki Torii, Kazue Hashimoto-Torii
Publikováno v:
Alcohol.
Autor:
Masaaki Torii, Hiroki Morizono, Shahid Mohammad, Anna C. Salzberg, Alexander I. Son, Yuka Imamura Kawasawa, Aiesha Basha, Kazue Hashimoto-Torii
Publikováno v:
Alcohol
Excessive alcohol consumption results in significant changes in gene expression and isoforms due to altered mRNA splicing. As such, an intriguing possibility is that disturbances in alternative splicing are involved in key pathological pathways trigg
Autor:
Masaaki Torii, Alexander I. Son, Julie Ziobro, Katherine Jones, Seiji Ishii, Axel Krieger, Kazue Hashimoto-Torii, Paul D. Morton, Justin Opfermann, Chima O. Oluigbo, John H. Abrahams, Judy S. Liu, Caroline McCue
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-16 (2017)
Local and controlled delivery of therapeutic agents directly into focally afflicted tissues is the ideal for the treatment of diseases that require direct interventions. However, current options are obtrusive, difficult to implement, and limited in t