Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Alexander I. Salter"'
Autor:
S. M. Shahjahan Miah, Chathuraka T. Jayasuriya, Alexander I. Salter, Emma C. Reilly, Céline Fugere, Wentian Yang, Qian Chen, Laurent Brossay
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
The ubiquitously expressed tyrosine phosphatase Src homology region 2 domain-containing phosphatase-2 (SHP-2, encoded by Ptpn11) is required for constitutive cellular processes including proliferation, differentiation, and the regulation of immune re
Externí odkaz:
https://doaj.org/article/50a394ed81284e4b95a06f6f2878920e
Autor:
Seth M. Pollack, Beverly Torok-Storb, Peter F. Moore, Stephen Gottschalk, Michael C. Jensen, Stanley R. Riddell, Alexander I. Salter, Bernard Seguin, Himaly Shinglot, Juliana Chi Kei Ng, Weiqing Jing, Ali Zhang, Amy B. Heimberger, Borislav A. Alexiev, Brian C. Schulte, Kraig Abrams, Brett A. Schroeder, Amanda Koehne, Cassandra Miller, Brian J. Hayes, Karan Kohli, R. Graeme Black, Shihong Zhang
One obstacle for human solid tumor immunotherapy research is the lack of clinically relevant animal models. In this study, we sought to establish a chimeric antigen receptor (CAR) T-cell treatment model for naturally occurring canine sarcomas as a mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32c913227bf6c523963cd395a6c7792b
https://doi.org/10.1158/1535-7163.c.6543363
https://doi.org/10.1158/1535-7163.c.6543363
Autor:
Seth M. Pollack, Beverly Torok-Storb, Peter F. Moore, Stephen Gottschalk, Michael C. Jensen, Stanley R. Riddell, Alexander I. Salter, Bernard Seguin, Himaly Shinglot, Juliana Chi Kei Ng, Weiqing Jing, Ali Zhang, Amy B. Heimberger, Borislav A. Alexiev, Brian C. Schulte, Kraig Abrams, Brett A. Schroeder, Amanda Koehne, Cassandra Miller, Brian J. Hayes, Karan Kohli, R. Graeme Black, Shihong Zhang
Supplementary Figure from B7-H3 Specific CAR T Cells for the Naturally Occurring, Spontaneous Canine Sarcoma Model
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09a1519317178c58461723ad4240fcf4
https://doi.org/10.1158/1535-7163.22522389
https://doi.org/10.1158/1535-7163.22522389
Autor:
Stanley R. Riddell, Andreas Plückthun, Michael C. Jensen, Jenna Voutsinas, Qian Wu, Paula L. Kosasih, Alexander I. Salter, Anusha Rajan, Ashwini Balakrishnan
FIGURE S4: Analysis of tonic signaling and function of trispecific and monspecific DARPin CARs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62147163f6153e573ed823046c46474c
https://doi.org/10.1158/1078-0432.22471247
https://doi.org/10.1158/1078-0432.22471247
Autor:
Stanley R. Riddell, Andreas Plückthun, Michael C. Jensen, Jenna Voutsinas, Qian Wu, Paula L. Kosasih, Alexander I. Salter, Anusha Rajan, Ashwini Balakrishnan
Purpose:The outgrowth of antigen-negative variants is a significant challenge for adoptive therapy with T cells that target a single specificity. Chimeric antigen receptors (CAR) are typically designed with one or two scFvs that impart antigen specif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7af3f5919e506f867f240d23dfbc46f7
https://doi.org/10.1158/1078-0432.c.6527819.v1
https://doi.org/10.1158/1078-0432.c.6527819.v1
Autor:
Stanley R. Riddell, Andreas Plückthun, Michael C. Jensen, Jenna Voutsinas, Qian Wu, Paula L. Kosasih, Alexander I. Salter, Anusha Rajan, Ashwini Balakrishnan
Supplementary Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::632fac219b9474149ca6058cdfedc551
https://doi.org/10.1158/1078-0432.22471241.v1
https://doi.org/10.1158/1078-0432.22471241.v1
Table S1 from Multispecific Targeting with Synthetic Ankyrin Repeat Motif Chimeric Antigen Receptors
Autor:
Stanley R. Riddell, Andreas Plückthun, Michael C. Jensen, Jenna Voutsinas, Qian Wu, Paula L. Kosasih, Alexander I. Salter, Anusha Rajan, Ashwini Balakrishnan
TABLE S1: 9-mer peptides in the scFv and DARPin sequences with predicted binding to the MHC class I supertype with a predicted binding affinity of less than 100 nM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22232923f3280934b150b081f385fc6b
https://doi.org/10.1158/1078-0432.22471238.v1
https://doi.org/10.1158/1078-0432.22471238.v1
Autor:
Shihong Zhang, R. Graeme Black, Karan Kohli, Brian J. Hayes, Cassandra Miller, Amanda Koehne, Brett A. Schroeder, Kraig Abrams, Brian C. Schulte, Borislav A. Alexiev, Amy B. Heimberger, Ali Zhang, Weiqing Jing, Juliana Chi Kei Ng, Himaly Shinglot, Bernard Seguin, Alexander I. Salter, Stanley R. Riddell, Michael C. Jensen, Stephen Gottschalk, Peter F. Moore, Beverly Torok-Storb, Seth M. Pollack
Publikováno v:
Molecular Cancer Therapeutics. 21:999-1009
One obstacle for human solid tumor immunotherapy research is the lack of clinically relevant animal models. In this study, we sought to establish a chimeric antigen receptor (CAR) T-cell treatment model for naturally occurring canine sarcomas as a mo
Autor:
Alexander I. Salter, Kayoko Hosaka, Andreas Lundqvist, Stina L. Wickström, Wei Tao, Shuzhong Yao, Xingkang He, Jieyu Wu, Yihai Cao, Jing Wu, Yanhong Duo, Qiqiao Du, Lasse Jensen, Rolf Kiessling, Lars Bräutigam, Xin Yin, Shuhang Qin, Yuguo Chen, Xu Jing
Publikováno v:
Proc Natl Acad Sci U S A
Lymphocyte-based immunotherapy has emerged as a breakthrough in cancer therapy for both hematologic and solid malignancies. In a subpopulation of cancer patients, this powerful therapeutic modality converts malignancy to clinically manageable disease
Autor:
Anusha Rajan, Alexander I. Salter, Qian Wu, Paula L. Kosasih, Michael C. Jensen, Stanley R. Riddell, Ashwini Balakrishnan, Jenna M. Voutsinas, Andreas Plückthun
Publikováno v:
Clin Cancer Res
Purpose: The outgrowth of antigen-negative variants is a significant challenge for adoptive therapy with T cells that target a single specificity. Chimeric antigen receptors (CAR) are typically designed with one or two scFvs that impart antigen speci