Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Alexander I. Alexandrov"'
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-8 (2023)
Abstract The CCT/TRiC chaperonin is found in the cytosol of all eukaryotic cells and assists protein folding in an ATP-dependent manner. The heterozygous double mutation T400P and R516H in subunit CCT2 is known to cause Leber congenital amaurosis (LC
Externí odkaz:
https://doaj.org/article/e98e2c60ced14a6cba5c8efee7189679
Autor:
Igor B. Levshin, Alexander Yu. Simonov, Alexey A. Panov, Natalia E. Grammatikova, Alexander I. Alexandrov, Eslam S. M. O. Ghazy, Vasiliy A. Ivlev, Michael O. Agaphonov, Alexey B. Mantsyzov, Vladimir I. Polshakov
Publikováno v:
Pharmaceuticals, Vol 17, Iss 6, p 723 (2024)
A series of hybrid compounds with triazole and thiazolidine nuclei connected by a linker has been synthesized and extensively studied. Various synthetic methods for the target compounds have been tested. A microbiological assessment of the obtained c
Externí odkaz:
https://doaj.org/article/13483073eed24242ad00227215e7d07b
Autor:
Maria V. Kulakova, Eslam S. M. O. Ghazy, Fedor Ryabov, Yaroslav M. Stanishevskiy, Michael O. Agaphonov, Alexander I. Alexandrov
Publikováno v:
Journal of Fungi, Vol 9, Iss 10, p 1033 (2023)
Assaying changes in the amount of DNA in single cells is a well-established method for studying the effects of various perturbations on the cell cycle. A drawback of this method is the need for a fixation procedure that does not allow for in vivo stu
Externí odkaz:
https://doaj.org/article/f3d0758beed94e81b66fa88c3c1936bf
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/c38f90ab9ff8434fbb959400802eeeaf
Autor:
Alexander I. Alexandrov, Valery N. Urakov, Sergey E. Dmitriev, Dmitri A. Bykov, Nadezhda E. Makarova, Olga V. Mitkevich, Yanislav S. Hrytseniuk, Desislava S. Makeeva, Artyom A. Egorov, Ivan V. Kulakovskiy
Publikováno v:
F1000Research, Vol 10 (2021)
In eukaryotes, stalled and collided ribosomes are recognized by several conserved multicomponent systems, which either block protein synthesis in situ and resolve the collision locally, or trigger a general stress response. Yeast ribosome-binding GTP
Externí odkaz:
https://doaj.org/article/1dc1d4566e1e4849b37a092295e42a10
Autor:
Alexander I. Alexandrov
Publikováno v:
Достоевский и мировая культура: Филологический журнал, Iss 3, Pp 151-156 (2019)
The article examines the ambiguity of the motives of light and darkness and their significance in F.M. Dostoevsky’s novel Netochka Nezvanova. These motives permeate the whole text, changing from the first part to the third part (conventionally). At
Externí odkaz:
https://doaj.org/article/7310ac7dbee74b23a37d024213fac47d
Publikováno v:
MethodsX, Vol 6, Iss , Pp 329-332 (2019)
Microscopy of multiple samples using slides and coverslips is time consuming and good images are sometimes difficult to obtain due to cell movement. Our method involves manual spotting of multiple cell samples onto solid-medium pads, which creates th
Externí odkaz:
https://doaj.org/article/1da546164eec4a138794154eec9962a1
Publikováno v:
Biomolecules, Vol 11, Iss 12, p 1884 (2021)
Amyloids are filamentous protein aggregates that are associated with a number of incurable diseases, termed amyloidoses. Amyloids can also manifest as infectious or heritable particles, known as prions. While just one prion is known in humans and ani
Externí odkaz:
https://doaj.org/article/84869c5e218946c0b8b55f7cfd412dc7
Publikováno v:
Journal of Fungi, Vol 7, Iss 10, p 884 (2021)
The biosynthesis of cyclic tetrapyrrol chromophores such as heme, siroheme, and chlorophyll involves the formation of fluorescent porphyrin precursors or compounds, which become fluorescent after oxidation. To identify Ogataea polymorpha mutations af
Externí odkaz:
https://doaj.org/article/c6bfe49a7828440da34147ac7f338f62
Autor:
Erika V. Grosfeld, Victoria A. Bidiuk, Olga V. Mitkevich, Eslam S. M. O. Ghazy, Vitaliy V. Kushnirov, Alexander I. Alexandrov
Publikováno v:
Journal of Fungi, Vol 7, Iss 11, p 886 (2021)
Cell death in response to distinct stimuli can manifest different morphological traits. It also depends on various cell death signaling pathways, extensively characterized in higher eukaryotes but less so in microorganisms. The study of cell death in
Externí odkaz:
https://doaj.org/article/e54b56a746f94ad18f358f1d5f5cc011