Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Alexander I Alexandrov"'
Autor:
Anton A Nizhnikov, Alexander I Alexandrov, Tatyana A Ryzhova, Olga V Mitkevich, Alexander A Dergalev, Michael D Ter-Avanesyan, Alexey P Galkin
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e116003 (2014)
Despite extensive study, progress in elucidation of biological functions of amyloids and their role in pathology is largely restrained due to the lack of universal and reliable biochemical methods for their discovery. All biochemical methods develope
Externí odkaz:
https://doaj.org/article/837709eedf4c406cba2ae25bde0fa025
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e29832 (2012)
BackgroundPolyglutamine expansion is responsible for several neurodegenerative disorders, among which Huntington disease is the most well-known. Studies in the yeast model demonstrated that both aggregation and toxicity of a huntingtin (htt) protein
Externí odkaz:
https://doaj.org/article/a126f683c7864c849bda5424748fc5ef
Autor:
Alexander I Alexandrov, Alla B Polyanskaya, Genrikh V Serpionov, Michael D Ter-Avanesyan, Vitaly V Kushnirov
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e46458 (2012)
Fragmentation of amyloid polymers by the chaperone Hsp104 allows them to propagate as prions in yeast. The factors which determine the frequency of fragmentation are unclear, though it is often presumed to depend on the physical strength of prion pol
Externí odkaz:
https://doaj.org/article/157a3fd95c4e4485873e4b54f1b8f2fe
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-8 (2023)
Abstract The CCT/TRiC chaperonin is found in the cytosol of all eukaryotic cells and assists protein folding in an ATP-dependent manner. The heterozygous double mutation T400P and R516H in subunit CCT2 is known to cause Leber congenital amaurosis (LC
Externí odkaz:
https://doaj.org/article/e98e2c60ced14a6cba5c8efee7189679
Autor:
Igor B. Levshin, Alexander Yu. Simonov, Alexey A. Panov, Natalia E. Grammatikova, Alexander I. Alexandrov, Eslam S. M. O. Ghazy, Vasiliy A. Ivlev, Michael O. Agaphonov, Alexey B. Mantsyzov, Vladimir I. Polshakov
Publikováno v:
Pharmaceuticals, Vol 17, Iss 6, p 723 (2024)
A series of hybrid compounds with triazole and thiazolidine nuclei connected by a linker has been synthesized and extensively studied. Various synthetic methods for the target compounds have been tested. A microbiological assessment of the obtained c
Externí odkaz:
https://doaj.org/article/13483073eed24242ad00227215e7d07b
Autor:
Maria V. Kulakova, Eslam S. M. O. Ghazy, Fedor Ryabov, Yaroslav M. Stanishevskiy, Michael O. Agaphonov, Alexander I. Alexandrov
Publikováno v:
Journal of Fungi, Vol 9, Iss 10, p 1033 (2023)
Assaying changes in the amount of DNA in single cells is a well-established method for studying the effects of various perturbations on the cell cycle. A drawback of this method is the need for a fixation procedure that does not allow for in vivo stu
Externí odkaz:
https://doaj.org/article/f3d0758beed94e81b66fa88c3c1936bf
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/c38f90ab9ff8434fbb959400802eeeaf
Autor:
Artem S Kushchenko, Artyom A. Egorov, Sergey E. Dmitriev, Valeriy N. Urakov, Alexander I. Alexandrov, Vadim N. Gladyshev, Roman O. Edakin, Desislava S. Makeeva, Ivan V. Kulakovskiy
Publikováno v:
Nucleic Acids Research
The Saccharomyces cerevisiae gene deletion collection is widely used for functional gene annotation and genetic interaction analyses. However, the standard G418-resistance cassette used to produce knockout mutants delivers strong regulatory elements
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7edffa67f93be53e7024a178d3058fb9
https://doi.org/10.1093/nar/gkab872
https://doi.org/10.1093/nar/gkab872
Autor:
Anna N. Tevyashova, Svetlana S. Efimova, Alexander I. Alexandrov, Eslam S.M.O. Ghazy, Elena N. Bychkova, Svetlana E. Solovieva, Georgy B. Zatonsky, Natalia E. Grammatikova, Lyubov G. Dezhenkova, Eleonora R. Pereverzeva, Elena B. Isakova, Olga S. Ostroumova, Olga A. Omelchuk, Vera V. Muravieva, Marina M. Krotova, Tatiana V. Priputnevich, Andrey E. Shchekotikhin
Publikováno v:
ACS infectious diseases.
Natamycin is a macrolide polyene antibiotic, characterized by a potent broad spectrum antifungal activity and low toxicity. However, it is not used for the treatment of systemic mycoses due to its low bioavailability and low solubility in aqueous sol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3221ef677f466a0ffe3766435c5d1ed5
https://pubmed.ncbi.nlm.nih.gov/36563312
https://pubmed.ncbi.nlm.nih.gov/36563312
Autor:
Erika V. Grosfeld, Vyacheslav S. Zhigarkov, Alexander I. Alexandrov, Nikita V. Minaev, Vladimir I. Yusupov
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 17; Pages: 9823
Laser-induced forward transfer (LIFT) is a useful technique for bioprinting using gel-embedded cells. However, little is known about the stresses experienced by cells during LIFT. This paper theoretically and experimentally explores the levels of las
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f1ff4eb2d0514059abc9092f7673d8e