Zobrazeno 1 - 10 of 27 pro vyhledávání: '"Alexander Hull"'
1
Akademický článek
Autophagic dysfunction and gut microbiota dysbiosis cause chronic immune activation in a Drosophila model of Gaucher disease.
Autor: Magda L Atilano, Alexander Hull, Catalina-Andreea Romila, Mirjam L Adams, Jacob Wildfire, Enric Ureña, Miranda Dyson, Jorge Ivan-Castillo-Quan, Linda Partridge, Kerri J Kinghorn
Publikováno v: PLoS Genetics, Vol 19, Iss 12, p e1011063 (2023)
Mutations in the GBA1 gene cause the lysosomal storage disorder Gaucher disease (GD) and are the greatest known genetic risk factors for Parkinson's disease (PD). Communication between the gut and brain and immune dysregulation are increasingly being
Externí odkaz: https://doaj.org/article/ac15018b4078410a9ca7e92d2fad388d
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2
Akademický článek
Enhanced insulin signalling ameliorates C9orf72 hexanucleotide repeat expansion toxicity in Drosophila
Autor: Magda L Atilano, Sebastian Grönke, Teresa Niccoli, Liam Kempthorne, Oliver Hahn, Javier Morón-Oset, Oliver Hendrich, Miranda Dyson, Mirjam Lisette Adams, Alexander Hull, Marie-Therese Salcher-Konrad, Amy Monaghan, Magda Bictash, Idoia Glaria, Adrian M Isaacs, Linda Partridge
Publikováno v: eLife, Vol 10 (2021)
G4C2 repeat expansions within the C9orf72 gene are the most common genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). The repeats undergo repeat-associated non-ATG translation to generate toxic dipeptide repeat pr
Externí odkaz: https://doaj.org/article/55824973121a40c69b33db796ae2c8b6
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3
Gba1 deletion causes immune hyperactivation and microbial dysbiosis through autophagic defects
Autor: Magda Luciana Atilano, Alexander Hull, Catalina-Andreea Romila, Mirjam L Adams, Jacob Wildfire, Enric Ureña, Miranda Dyson, Jorge Ivan-Castillo-Quan, Linda Partridge, Kerri J. Kinghorn
Mutations in theGBA1gene cause the lysosomal storage disorder Gaucher disease (GD) and are the greatest genetic risk factor for Parkinson’s disease (PD). Communication between gut and brain and immune dysregulation are increasingly being implicated
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::84a14fd5dce22d7a72efd4a5b97e4fb9
https://doi.org/10.1101/2022.12.15.520449
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6
Enhanced insulin signalling ameliorates C9orf72 hexanucleotide repeat expansion toxicity in Drosophila
Autor: Oliver Hahn, Sebastian Grönke, Oliver Hendrich, Alexander Hull, Miranda C. Dyson, Adrian M. Isaacs, Idoia Glaria, Magda L. Atilano, Linda Partridge, Liam Kempthorne, Amy Monaghan, Javier Morón-Oset, Marie-Therese Salcher-Konrad, Teresa Niccoli, Magda Bictash, Mirjam Lisette Adams
Publikováno v: Elife
eLife
eLife, Vol 10 (2021)
G4C2 repeat expansions within the C9orf72 gene are the most common genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD). The repeats undergo repeat-associated non-ATG translation to generate toxic dipeptide repeat pr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::049e2373f4ec78a5ad540b032b74cbe5
https://hdl.handle.net/21.11116/0000-000A-FAE7-8
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