Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Alexander Hempelmann"'
Autor:
Beatrice Casati, Joseph Peter Verdi, Alexander Hempelmann, Maximilian Kittel, Andrea Gutierrez Klaebisch, Bianca Meister, Sybille Welker, Sonal Asthana, Salvatore Di Giorgio, Pavle Boskovic, Ka Hou Man, Meike Schopp, Paul Adrian Ginno, Bernhard Radlwimmer, Charles Erec Stebbins, Thomas Miethke, Fotini Nina Papavasiliou, Riccardo Pecori
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-11 (2022)
SARS-CoV-2 antigen tests are commonly used point-of-care tests and provide rapid results but lack sensitivity. Here, the authors present a new point-of-care approach for COVID-19 diagnosis, “ADESSO”, which outperforms antigen tests on clinical sa
Externí odkaz:
https://doaj.org/article/62f43b1d9bf94791a8bc45d89c97e351
Autor:
Alexander Hempelmann, Laura Hartleb, Monique van Straaten, Hamidreza Hashemi, Johan P. Zeelen, Kevin Bongers, F. Nina Papavasiliou, Markus Engstler, C. Erec Stebbins, Nicola G. Jones
Publikováno v:
Cell Reports, Vol 37, Iss 5, Pp 109923- (2021)
Summary: The dense variant surface glycoprotein (VSG) coat of African trypanosomes represents the primary host-pathogen interface. Antigenic variation prevents clearing of the pathogen by employing a large repertoire of antigenically distinct VSG gen
Externí odkaz:
https://doaj.org/article/c3acb4d7657a4e0b8cad190d14971cdf
Publikováno v:
Advances in Astronomy, Vol 2010 (2010)
The fully automatic reduction pipeline for the blue channel of the HEROS spectrograph of the Hamburg Robotic Telescope (HRT) is presented. This pipeline is started automatically after finishing the night-time observations and calibrations. The pipeli
Externí odkaz:
https://doaj.org/article/79991c3efb6e47a698a95b5bddf653a4
Autor:
Natalie Wiedemar, F. Nina Papavasiliou, Johan Zeelen, Hamidreza Hashemi, Joseph Verdi, Silvan Hälg, C. Erec Stebbins, Kathryn Perez, Pascal Mäser, Alexander Hempelmann, Philip D. Jeffrey, Monique van Straaten
Publikováno v:
Nature microbiology
Suramin has been a primary early-stage treatment for African trypanosomiasis for nearly 100 yr. Recent studies revealed that trypanosome strains that express the variant surface glycoprotein (VSG) VSGsur possess heightened resistance to suramin. Here
Autor:
Beatrice Casati, Joseph Peter Verdi, Alexander Hempelmann, Maximilian Kittel, Andrea Gutierrez Klaebisch, Bianca Meister, Sybille Welker, Sonal Asthana, Salvatore Di Giorgio, Pavle Boskovic, Ka Hou Man, Meike Schopp, Paul Adrian Ginno, Bernhard Radlwimmer, Charles Erec Stebbins, Thomas Miethke, Fotini Nina Papavasiliou, Riccardo Pecori
Publikováno v:
Nature communications. 13(1)
During the ongoing COVID-19 pandemic, PCR testing and antigen tests have proven critical for helping to stem the spread of its causative agent, SARS-CoV-2. However, these methods suffer from either general applicability and/or sensitivity. Moreover,
Autor:
Beatrice Casati, Joseph Peter Verdi, Alexander Hempelmann, Maximilian Kittel, Andrea Gutierrez Klaebisch, Bianca Meister, Sybille Welker, Sonal Asthana, Pavle Boskovic, Ka Hou Man, Meike Schopp, Paul Ginno, Bernhard Radlwimmer, Charles Erec Stebbins, Thomas Miethke, Fotini Nina Papavasiliou, Riccardo Pecori
With the coronavirus disease 19 (COVID-19) pandemic now deep into its second year, widespread testing for the detection of the causative severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is fundamental. The gold standard reverse transcript
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e59b643a50fec06aed5d2aecb66cfe56
https://doi.org/10.1101/2021.06.17.21258371
https://doi.org/10.1101/2021.06.17.21258371
Autor:
Hamidreza Hashemi, Laura Hartleb, Johan Zeelen, F. Nina Papavasiliou, Markus Engstler, C. Erec Stebbins, Nicola G. Jones, Monique van Straaten, Alexander Hempelmann
The dense Variant Surface Glycoprotein (VSG) coat of African trypanosomes represents the primary host-pathogen interface. Antigenic variation prevents clearing of the pathogen by employing a large repertoire of antigenically distinct VSG genes, thus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4889a52744caf04d9b42fdffaf46145a
https://doi.org/10.1101/2021.01.13.426364
https://doi.org/10.1101/2021.01.13.426364
Autor:
Alexander, Hempelmann, Laura, Hartleb, Monique, van Straaten, Hamidreza, Hashemi, Johan P, Zeelen, Kevin, Bongers, F Nina, Papavasiliou, Markus, Engstler, C Erec, Stebbins, Nicola G, Jones
Publikováno v:
Cell Reports, Vol 37, Iss 5, Pp 109923-(2021)
Summary: The dense variant surface glycoprotein (VSG) coat of African trypanosomes represents the primary host-pathogen interface. Antigenic variation prevents clearing of the pathogen by employing a large repertoire of antigenically distinct VSG gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::a8736b87e0328d65af8a2351f9b23ec8
https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/27028
https://opus.bibliothek.uni-wuerzburg.de/frontdoor/index/index/docId/27028
Autor:
Joseph Verdi, Natalie Wiedemar, Monique van Straaten, Philip D. Jeffrey, Pascal Maeser, Johan Zeelen, F. Nina Papavasiliou, Alexander Hempelmann, Hamidreza Hashemi, Kathryn Perez, Silvan Haelg, C. Erec Stebbins
Suramin has been a primary early-stage treatment for African trypanosomiasis for nearly one hundred years. Recent studies revealed that trypanosome strains that express the Variant Surface Glycoprotein VSGsur possess heightened resistance to suramin.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d48a71908d63639d245f0b3cb555789e
https://doi.org/10.1101/2020.06.04.134106
https://doi.org/10.1101/2020.06.04.134106
Autor:
Michelle K. Haas, Jessica M. Devant, Kerstin Ruoff, Turgay Kilic, Alessa R. Ringel, Celina Geiss, Grant S. Hansman, Anna D. Koromyslova, Alexander Hempelmann, Juliane Graf, Imme Roggenbach
Publikováno v:
Journal of Virology
The discovery of vulnerable regions on norovirus particles is instrumental in the development of effective inhibitors, particularly for GI noroviruses that are genetically diverse. Analysis of these GI.1-specific Nanobodies has shown that similar to