Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Alexander Hayn"'
Autor:
Frank Sauer, Steffen Grosser, Mehrgan Shahryari, Alexander Hayn, Jing Guo, Jürgen Braun, Susanne Briest, Benjamin Wolf, Bahriye Aktas, Lars‐Christian Horn, Ingolf Sack, Josef A. Käs
Publikováno v:
Advanced Science, Vol 10, Iss 26, Pp n/a-n/a (2023)
Abstract Cancer progression is caused by genetic changes and associated with various alterations in cell properties, which also affect a tumor's mechanical state. While an increased stiffness has been well known for long for solid tumors, it has limi
Externí odkaz:
https://doaj.org/article/9d29f8eccd8d41b8a1a12887ee8343b9
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
The majority of investigations of cancer cells have been performed in an oversimplified 2D in vitro environment. In the last decade there is a trend toward more sophisticated 3D in vitro cell culture model systems that can bridge the existing gap bet
Externí odkaz:
https://doaj.org/article/374126c5e4ff4e858974728aea98d589
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract The knowledge of cell mechanics is required to understand cellular processes and functions, such as the movement of cells, and the development of tissue engineering in cancer therapy. Cell mechanical properties depend on a variety of factors
Externí odkaz:
https://doaj.org/article/e22d2900ebba416faa06c932736da35e
PINCH1 Promotes Fibroblast Migration in Extracellular Matrices and Influences Their Mechanophenotype
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Cell migration performs a critical function in numerous physiological processes, including tissue homeostasis or wound healing after tissue injury, as well as pathological processes that include malignant progression of cancer. The efficiency of cell
Externí odkaz:
https://doaj.org/article/40b574c0bc994ef28c4b731c6f7ac086
Publikováno v:
Polymers, Vol 14, Iss 20, p 4434 (2022)
Biopolymer blends are advantageous materials with novel properties that may show performances way beyond their individual constituents. Collagen elastin hybrid gels are a new representative of such materials as they employ elastin’s thermo switchin
Externí odkaz:
https://doaj.org/article/6090dbe57c05419c8cc18920313c258c
Autor:
Francisco Drusso Martinez-Garcia, Tony Fischer, Alexander Hayn, Claudia Tanja Mierke, Janette Kay Burgess, Martin Conrad Harmsen
Publikováno v:
Gels, Vol 8, Iss 9, p 535 (2022)
The extracellular matrix (ECM) is a three-dimensional, acellular scaffold of living tissues. Incorporating the ECM into cell culture models is a goal of cell biology studies and requires biocompatible materials that can mimic the ECM. Among such mate
Externí odkaz:
https://doaj.org/article/3c81015975f14ec4a84ed1b323a806e7
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Cell motility under physiological and pathological conditions including malignant progression of cancer and subsequent metastasis are founded on environmental confinements. During the last two decades, three-dimensional cell migration has been studie
Externí odkaz:
https://doaj.org/article/7a529500f971438ab8b30b560f930a03
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
The migration and invasion of cancer cells through 3D confined extracellular matrices is coupled to cell mechanics and the mechanics of the extracellular matrix. Cell mechanics is mainly determined by both the mechanics of the largest organelle in th
Externí odkaz:
https://doaj.org/article/4aeadc4c73a14019b83f563166c790c6
Autor:
Alexander Hayn, Janette Burgess, Tony Fischer, Claudia Tanja Mierke, Francisco Drusso Martinez Garcia, Martin Harmsen
Publikováno v:
Gels, 8(9):535. MDPI AG
The extracellular matrix (ECM) is a three-dimensional, acellular scaffold of living tissues. Incorporating the ECM into cell culture models is a goal of cell biology studies and requires biocompatible materials that can mimic the ECM. Among such mate
Autor:
Jens Ulrich Rüffer, Alexander Hayn, Vanessa Romotzky, Julia Strupp, Judith Grümmer, Raymond Voltz
Publikováno v:
Palliativesupportive care. 17(2)
ObjectiveWe aimed to elucidate the views on life as narrated by patients in palliative care (PC) to find out what patients deem to be essential in their life, whether something has changed concerning their view of life in light of the disease, and wh