Zobrazeno 1 - 4 of 4 pro vyhledávání: '"Alexander Hall Hickman"'
1
Akademický článek
Apparent RNA bridging between PRC2 and chromatin is an artifact of non-specific chromatin precipitation upon RNA degradation
Autor: Alexander Hall Hickman, Richard G. Jenner
Publikováno v: Cell Reports, Vol 43, Iss 3, Pp 113856- (2024)
Summary: Polycomb repressive complex 2 (PRC2) modifies chromatin to maintain repression of genes specific for other cell lineages. In vitro, RNA inhibits PRC2 activity, but the effect of RNA on PRC2 in cells is less clear, with studies concluding tha
Externí odkaz: https://doaj.org/article/132b5495278744eab73b7590c4ca1319
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2
Akademický článek
HNRNPM controls circRNA biogenesis and splicing fidelity to sustain cancer cell fitness
Autor: Jessica SY Ho, Federico Di Tullio, Megan Schwarz, Diana Low, Danny Incarnato, Florence Gay, Tommaso Tabaglio, JingXian Zhang, Heike Wollmann, Leilei Chen, Omer An, Tim Hon Man Chan, Alexander Hall Hickman, Simin Zheng, Vladimir Roudko, Sujun Chen, Alcida Karz, Musaddeque Ahmed, Housheng Hansen He, Benjamin D Greenbaum, Salvatore Oliviero, Michela Serresi, Gaetano Gargiulo, Karen M Mann, Eva Hernando, David Mulholland, Ivan Marazzi, Dave Keng Boon Wee, Ernesto Guccione
Publikováno v: eLife, Vol 10 (2021)
High spliceosome activity is a dependency for cancer cells, making them more vulnerable to perturbation of the splicing machinery compared to normal cells. To identify splicing factors important for prostate cancer (PCa) fitness, we performed pooled
Externí odkaz: https://doaj.org/article/bb9c4ec7e7bc4cdb8d75d13a76778524
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3
HNRNPM controls circRNA biogenesis and splicing fidelity to sustain cancer cell fitness
Autor: Ernesto Guccione, Heike Wollmann, Gaetano Gargiulo, Federico Di Tullio, Tim Chan, Diana Low, Danny Incarnato, David J. Mulholland, Leilei Chen, Vladimir Roudko, Sujun Chen, Benjamin Greenbaum, Simin Zheng, Omer An, Musaddeque Ahmed, Megan C. Schwarz, Ivan Marazzi, Michela Serresi, Tommaso Tabaglio, Jingxian Zhang, Alexander Hall Hickman, Eva Hernando, Karen M Mann, Jessica Sy Ho, Dave Keng Boon Wee, Alcida Karz, Housheng Hansen He, Salvatore Oliviero
Publikováno v: eLife, Vol 10 (2021)
eLife, 10:e59654. ELIFE SCIENCES PUBLICATIONS LTD
eLife
High spliceosome activity is a dependency for cancer cells, making them more vulnerable to perturbation of the splicing machinery compared to normal cells. To identify splicing factors important for prostate cancer (PCa) fitness, we performed pooled
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68f315b28e6e3a40591e31b95c6cd512
http://edoc.mdc-berlin.de/20334/1/20334oa.pdf
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